Genetic Analysis of Growth Inhibition by GAL 4-IKB-o . . in Saccharomyces cerevisiae

American Cancer Society, from the Children’s Leukemia Research Association, Inc., and from the Council for Tobacco Research-USA, Inc.. P. J. M. was supported by a graduate scholarship from the National Sciences and Engineering Research Council of Canada. A. M. S. was a participant in the Research Science Institute sponsored by the Center for Excellence in Education and the Massachusetts Institute of Technology. T. D. G. was partially supported by a Faculty Research Award from the American Cancer Society. 2 These two authors contributed equally to the publication. 3 Present address: Johns Hopkins Oncology Center, Johns Hopkins Medical School, 424 North Bond Street, Baltimore, MD 21231-1001. 4 To whom requests for reprints should be addressed at Boston University, Biology Department, 5 Cummington Street, Boston, MA 02215. 5 The abbreviations used are: 1KB, inhibitor of KB binding; NF-KB, nuclear factor KB; ANK, ankryin; ts, temperature-sensitive; GST, glutathione S-transferase. Vol. 6, 789-798, july 1995 Cell Growth & Differentiation 789

[1]  L. Guarente,et al.  ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex , 1995, Molecular and cellular biology.

[2]  L. Guarente,et al.  Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[3]  T. Rabbitts,et al.  Chromosomal translocations in human cancer , 1994, Nature.

[4]  B. Cullen,et al.  Mutational analysis of the transcription activation domain of RelA: identification of a highly synergistic minimal acidic activation module , 1994, Molecular and cellular biology.

[5]  T. Gilmore,et al.  Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1 , 1994, Journal of virology.

[6]  P. Baeuerle,et al.  A proteasome inhibitor prevents activation of NF‐kappa B and stabilizes a newly phosphorylated form of I kappa B‐alpha that is still bound to NF‐kappa B. , 1994, The EMBO journal.

[7]  S. Berger,et al.  Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors. , 1994, The EMBO journal.

[8]  T. Gilmore,et al.  NF-kappa B p100 is one of the high-molecular-weight proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells , 1993, Journal of virology.

[9]  R. Taub,et al.  I kappa B alpha can localize in the nucleus but shows no direct transactivation potential. , 1993, Oncogene.

[10]  K. Middleton,et al.  An essential yeast protein, CBF5p, binds in vitro to centromeres and microtubules , 1993, Molecular and cellular biology.

[11]  P. Morin,et al.  GAL4-lϰBα and GAL4-lϰBγ activate transcription by different mechanisms , 1993 .

[12]  G. Mosialos,et al.  v-Rel and c-Rel are differentially affected by mutations at a consensus protein kinase recognition sequence. , 1993, Oncogene.

[13]  S. Berger,et al.  Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains , 1992, Cell.

[14]  P. Morin,et al.  The C terminus of the NF-χB p50 precursor and an IχB isoform contain transcription activation domains , 1992 .

[15]  V. Bennett,et al.  The ANK repeat: a ubiquitous motif involved in macromolecular recognition. , 1992, Trends in cell biology.

[16]  M. Boguski,et al.  Comparative analysis of the β transducin family with identification of several new members including PWP1, a nonessential gene of Saccharomyces cerevisiae that is divergently transcribed from NMT1 , 1992, Proteins.

[17]  M. Miyagi,et al.  NH2-terminal acetylation of ribosomal proteins of Saccharomyces cerevisiae. , 1992, The Journal of biological chemistry.

[18]  E. Otaka,et al.  Sequence and functional similarity between a yeast ribosomal protein and the Escherichia coli S5 ram protein , 1990, Molecular and cellular biology.

[19]  H. Ronne,et al.  Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins. , 1990, The EMBO journal.

[20]  A. Capobianco,et al.  Cloning and expression of a chicken c-rel cDNA: unlike p59v-rel, p68c-rel is a cytoplasmic protein in chicken embryo fibroblasts. , 1990, Oncogene.

[21]  Susumu,et al.  Identification and characterization of genes and mutants for an N‐terminal acetyltransferase from yeast. , 1989, The EMBO journal.

[22]  K. Isono,et al.  Ribosomal protein modification in Escherichia coli , 2004, Molecular and General Genetics MGG.

[23]  A. Goldberg,et al.  The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. , 1994, Cell.

[24]  I. Wool.  The Bifunctional Nature of Ribosomal Proteins and Speculations on Their Origins , 1993 .

[25]  P. Morin,et al.  The I kappa B proteins: members of a multifunctional family. , 1993, Trends in genetics : TIG.