Subicular projections to the posterior cingulate cortex in rats

Abstract The subicular cortex and not Ammon's horn has been previously shown to receive afferents from the posterior cingulate cortex. Utilizing the techniques of horseradish peroxidase histochemistry and amino acid autoradiography we present evidence that in the rat the dorsal subicular cortex has a reciprocal connection with the posterior cingulate cortex. The prosubiculum has a small projection to the ventral portion of the retrosplenialis granularis. The presubiculum has the most massive projection to layers III (IV) of the retrosplenial is granularis which extends dorsally up to the border of the retrosplenialis agranularis. Relations of the presubicular component of the hippocampal formation with other components of the Papez circuit are discussed.

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