Urinary excretion of several metabolites in persons accidentally exposed to ionizing radiation.

BS>Urinary concentrations of creatine, beta -aminoisobutyric acid, pyrrole --carboxylic acid, and free hydroxyproline were determined in human subjects accidentally exposed to ionizing radiation at various time intervals after exposure. The range of doses of radiation varied from about 100 to 4000 rads. Increased concentrations of creatine and beta -aminoisobutyric acid in urine were found in most of the patients. Excretion of free hydroxyproline was decreased in the three most heavily exposed patients, whereas pyrrolecarboxylic acid was increased only in the fatally injured patient. (auth)