Restoration of replication-defective dengue type 1 virus bearing mutations in the N-terminal cytoplasmic portion of NS4A by additional mutations in NS4B

[1]  S. Tajima,et al.  A single mutation in the Japanese encephalitis virus E protein (S123R) increases its growth rate in mouse neuroblastoma cells and its pathogenicity in mice. , 2010, Virology.

[2]  A. Strongin,et al.  NS4A regulates the ATPase activity of the NS3 helicase: a novel cofactor role of the non-structural protein NS4A from West Nile virus. , 2009, The Journal of general virology.

[3]  Wei-Yong Lin,et al.  Interferon antagonist function of Japanese encephalitis virus NS4A and its interaction with DEAD-box RNA helicase DDX42. , 2008, Virus research.

[4]  C. Seeger,et al.  Differential Effects of Mutations in NS4B on West Nile Virus Replication and Inhibition of Interferon Signaling , 2007, Journal of Virology.

[5]  M. Bloom,et al.  Identification of Residues Critical for the Interferon Antagonist Function of Langat Virus NS 5 Reveals a Role for the RNA-Dependent RNA Polymerase Domain , 2006 .

[6]  Ralf Bartenschlager,et al.  The Non-structural Protein 4A of Dengue Virus Is an Integral Membrane Protein Inducing Membrane Alterations in a 2K-regulated Manner* , 2007, Journal of Biological Chemistry.

[7]  Charles M. Rice,et al.  Flaviviridae :T he Viruses and Their Replication , 2007 .

[8]  A. Sampath,et al.  Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA. , 2006, The Journal of general virology.

[9]  Ren-Jye Lin,et al.  Blocking of Interferon-Induced Jak-Stat Signaling by Japanese Encephalitis Virus NS5 through a Protein Tyrosine Phosphatase-Mediated Mechanism , 2006, Journal of Virology.

[10]  A. Barrett,et al.  A single amino acid substitution in the central portion of the West Nile virus NS4B protein confers a highly attenuated phenotype in mice. , 2006, Virology.

[11]  J. Mackenzie,et al.  Regulated Cleavages at the West Nile Virus NS4A-2K-NS4B Junctions Play a Major Role in Rearranging Cytoplasmic Membranes and Golgi Trafficking of the NS4A Protein , 2006, Journal of Virology.

[12]  R. Bartenschlager,et al.  Subcellular Localization and Membrane Topology of the Dengue Virus Type 2 Non-structural Protein 4B* , 2006, Journal of Biological Chemistry.

[13]  S. Tajima,et al.  Nineteen nucleotides in the variable region of 3' non-translated region are dispensable for the replication of dengue type 1 virus in vitro. , 2006, Virus research.

[14]  J. Muñoz-Jordán,et al.  Inhibition of Alpha/Beta Interferon Signaling by the NS4B Protein of Flaviviruses , 2005, Journal of Virology.

[15]  J. Hayashi,et al.  West Nile Virus Inhibits the Signal Transduction Pathway of Alpha Interferon , 2005, Journal of Virology.

[16]  P. Shi,et al.  Inhibition of Interferon Signaling by the New York 99 Strain and Kunjin Subtype of West Nile Virus Involves Blockage of STAT1 and STAT2 Activation by Nonstructural Proteins , 2005, Journal of Virology.

[17]  Bachti Alisjahbana,et al.  Epidemiology of dengue and dengue hemorrhagic fever in a cohort of adults living in Bandung, West Java, Indonesia. , 2005, The American journal of tropical medicine and hygiene.

[18]  Adolfo García-Sastre,et al.  Inhibition of interferon signaling by dengue virus , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[19]  B. Murphy,et al.  Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells. , 2003, Vaccine.

[20]  B. Murphy,et al.  A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4. , 2003, Virology.

[21]  W. Liu,et al.  Molecular and Functional Analyses of Kunjin Virus Infectious cDNA Clones Demonstrate the Essential Roles for NS2A in Virus Assembly and for a Nonconservative Residue in NS3 in RNA Replication , 2003, Journal of Virology.

[22]  J. Mackenzie,et al.  Kunjin RNA replication and applications of Kunjin replicons. , 2003, Advances in virus research.

[23]  Y. S. Lin,et al.  Immunopathogenesis of dengue virus infection. , 2001, Journal of biomedical science.

[24]  S C Wu,et al.  Complete nucleotide sequence and cell-line multiplication pattern of the attenuated variant CH2195LA of Japanese encephalitis virus. , 2001, Virus research.

[25]  R. Hall,et al.  Efficient trans-Complementation of the Flavivirus Kunjin NS5 Protein but Not of the NS1 Protein Requires Its Coexpression with Other Components of the Viral Replicase , 1999, Journal of Virology.

[26]  C. Rice,et al.  Genetic Interaction of Flavivirus Nonstructural Proteins NS1 and NS4A as a Determinant of Replicase Function , 1999, Journal of Virology.

[27]  E. G. Westaway,et al.  Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A. , 1998, Virology.

[28]  D. Gubler,et al.  Dengue and Dengue Hemorrhagic Fever , 1998, Clinical Microbiology Reviews.

[29]  L. Rosen.  The Emperor's New Clothes revisited, or reflections on the pathogenesis of dengue hemorrhagic fever. , 1977, The American journal of tropical medicine and hygiene.