Detection of the tagged or untagged photons in acousto-optic imaging of thick highly scattering media by photorefractive adaptive holography

We propose an original adaptive wavefront holographic setup based on the photorefractive effect (PR), to make real-time measurements of acousto-optic signals in thick scattering media, with a high flux collection at high rates for breast tumor detection. We describe here our present state of the art and understanding on the problem of breast imaging with PR detection of the acousto-optic signal.

[1]  L Wang,et al.  MCML--Monte Carlo modeling of light transport in multi-layered tissues. , 1995, Computer methods and programs in biomedicine.

[2]  Lihong V. Wang,et al.  Sonoluminescence tomography of turbid media , 1999, Photonics West - Biomedical Optics.

[3]  A. Boccara,et al.  Heterodyne detection of multiply scattered monochromatic light with a multipixel detector. , 2005, Optics letters.

[4]  G Roosen,et al.  Photorefractive detection of tagged photons in ultrasound modulated optical tomography of thick biological tissues. , 2004, Optics express.

[5]  G Roosen,et al.  Theoretical description of the photorefractive detection of the ultrasound modulated photons in scattering media. , 2005, Optics express.

[6]  Bruno Sfez,et al.  In vivo demonstration of the ultrasound-modulated light technique. , 2003, Journal of the Optical Society of America. A, Optics, image science, and vision.

[7]  S L Jacques,et al.  Continuous-wave ultrasonic modulation of scattered laser light to image objects in turbid media. , 1995, Optics letters.

[8]  L. Kou,et al.  Refractive indices of water and ice in the 0.65- to 2.5-µm spectral range. , 1993, Applied optics.

[9]  S. Lévêque-Fort,et al.  Three-dimensional acousto-optic imaging in biological tissues with parallel signal processing. , 2001, Applied optics.

[10]  B G Sfez,et al.  Direct, noninvasive detection of photon density in turbid media. , 2002, Optics letters.

[11]  Gopi Maguluri,et al.  Computations of the acoustically induced phase shifts of optical paths in acoustophotonic imaging with photorefractive-based detection. , 2005, Applied optics.

[12]  Geng Ku,et al.  Transmission- and side-detection configurations in ultrasound-modulated optical tomography of thick biological tissues. , 2003, Applied optics.

[13]  M. Gross,et al.  Shot-noise detection of ultrasound-tagged photons in ultrasound-modulated optical imaging. , 2003, Optics letters.

[14]  Azriel Z. Genack,et al.  Acousto-optic tomography with multiply scattered light , 1997 .

[15]  Britton Chance,et al.  Photon Migration and Imaging in Random Media and Tissues , 1993 .

[16]  Glen William Brooksby,et al.  Comprehensive approach to breast cancer detection using light: photon localization by ultrasound modulation and tissue characterization by spectral discrimination , 1993, Photonics West - Lasers and Applications in Science and Engineering.

[17]  Arthur E. T. Chiou,et al.  Cross-polarization photorefractive two-beam coupling in gallium arsenide , 1988 .

[18]  Philippe Delaye,et al.  Novel theoretical aspects on photorefractive ultrasonic detection and implementation of a sensor with an optimum sensitivity , 1997 .

[19]  Sandrine Que-Fort Three-Dimensional Acousto-Optic Imaging in Biological Tissues with Parallel Signal Processing , 2001 .

[20]  G. Maret,et al.  Ultrasonic modulation of multiply scattered light , 1995 .

[21]  A. Boccara,et al.  Pulsed acousto-optic imaging in dynamic scattering media with heterodyne parallel speckle detection. , 2005, Optics letters.

[22]  Charles A DiMarzio,et al.  Imaging in diffuse media with pulsed-ultrasound-modulated light and the photorefractive effect. , 2005, Applied optics.

[23]  L V Wang,et al.  Sonoluminescent tomography of strongly scattering media. , 1998, Optics letters.

[24]  Sandrine Leveque-Fort,et al.  In situ local tissue characterization and imaging by backscattering acousto-optic imaging , 2001 .

[25]  Z. Kotler,et al.  Ultrasound tagged light imaging in turbid media in a reflectance geometry. , 2000, Optics letters.

[26]  Gérald Roosen,et al.  Transmission of time modulated optical signals through an absorbing photorefractive crystal , 1995 .

[27]  Gopi Maguluri,et al.  Detection of ultrasound-modulated photons in diffuse media using the photorefractive effect. , 2004, Optics letters.

[28]  Photorefractive wave mixing in undoped liquid encapsulated Czochralski GaAs at 1.5 μm: Validation of photorefractive modeling , 1994 .

[29]  Emmanuel Bossy,et al.  Fusion of conventional ultrasound imaging and acousto-optic sensing by use of a standard pulsed-ultrasound scanner. , 2005, Optics letters.

[30]  A. Bloom Quantum Electronics , 1972, Nature.

[31]  In situ monitoring of the photorefractive response time in a self-adaptive wavefront holography setup developed for acousto-optic imaging. , 2007, Optics express.

[32]  A. Boccara,et al.  Ultrasonic tagging of photon paths in scattering media: parallel speckle modulation processing. , 1999, Optics letters.