Growth response to antiretroviral treatment in HIV‐infected children: a cohort study from Lilongwe, Malawi

Objective  Malnutrition is common in HIV‐infected children in Africa and an indication for antiretroviral treatment (ART). We examined anthropometric status and response to ART in children treated at a large public‐sector clinic in Malawi.

[1]  S. Filteau The HIV‐exposed, uninfected African child , 2009, Tropical medicine & international health : TM & IH.

[2]  A Sarah Walker,et al.  Differences in Factors Associated With Initial Growth, CD4, and Viral Load Responses to ART in HIV-Infected Children in Kampala, Uganda, and the United Kingdom/Ireland , 2008, Journal of acquired immune deficiency syndromes.

[3]  A. Bandyopadhyay,et al.  Effect of pre-existing malnutrition on growth parameters in HIV-infected children commencing antiretroviral therapy , 2008, Annals of tropical paediatrics.

[4]  A. Tomkins,et al.  Nutritional recovery in HIV-infected and HIV-uninfected children with severe acute malnutrition , 2008, Archives of Disease in Childhood.

[5]  W. Moss,et al.  Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa. , 2008, The Lancet. Infectious diseases.

[6]  A. Tomkins,et al.  The impact of HIV on mortality during in-patient rehabilitation of severely malnourished children in Malawi. , 2008, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[7]  F. Dabis,et al.  Cohort profile: the paediatric antiretroviral treatment programmes in lower-income countries (KIDS-ART-LINC) collaboration. , 2008, International journal of epidemiology.

[8]  K. Maleta,et al.  HIV prevalence in severely malnourished children admitted to nutrition rehabilitation units in Malawi: Geographical & seasonal variations a cross-sectional study , 2008, BMC pediatrics.

[9]  M. Chhagan,et al.  Case management of HIV-infected severely malnourished children: challenges in the area of highest prevalence , 2008, The Lancet.

[10]  W. Chan,et al.  Growth in HIV-infected children receiving antiretroviral therapy at a pediatric infectious diseases clinic in Uganda. , 2008, AIDS patient care and STDs.

[11]  H. Zar,et al.  Markers for predicting mortality in untreated HIV-infected children in resource-limited settings: a meta-analysis , 2008, AIDS.

[12]  A. Muula,et al.  Human resources requirements for highly active antiretroviral therapy scale-up in Malawi , 2007, BMC Health Services Research.

[13]  E. Molyneux,et al.  Experience of anti-retroviral treatment for HIV-infected children in Malawi: the 1st 12 months , 2007, Annals of tropical paediatrics.

[14]  B. Chi,et al.  Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia. , 2007, JAMA.

[15]  K. Mandaliya,et al.  Efficacy of Highly Active Antiretroviral Therapy in HIV-1–Infected Children in Kenya , 2007, Pediatrics.

[16]  H. Chiang,et al.  Risk factors for early mortality in children on adult fixed-dose combination antiretroviral treatment in a central hospital in Malawi , 2007, AIDS.

[17]  J. Overbaugh,et al.  Early Response to Highly Active Antiretroviral Therapy in HIV-1-Infected Kenyan Children , 2007, Journal of acquired immune deficiency syndromes.

[18]  C. Kankasa,et al.  The impact of daily cotrimoxazole prophylaxis and antiretroviral therapy on mortality and hospital admissions in HIV-infected Zambian children. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[19]  J. Bellón,et al.  Impact on Weight and Height With the Use of HAART in HIV-Infected Children , 2007, The Pediatric infectious disease journal.

[20]  C. Yiannoutsos,et al.  Outcomes of HIV-Infected Orphaned and Non-Orphaned Children on Antiretroviral Therapy in Western Kenya , 2006, Journal of acquired immune deficiency syndromes.

[21]  T. Taylor,et al.  Observational Cohort Study of HIV-Infected African Children , 2006, The Pediatric infectious disease journal.

[22]  J. Lindsey,et al.  Growth of Human Immunodeficiency Virus-Infected Children Receiving Highly Active Antiretroviral Therapy , 2005, The Pediatric infectious disease journal.

[23]  S. Hirschfeld,et al.  Growth as a part of the composite endpoint in paediatric antiretroviral clinical trials. , 2004, The Journal of antimicrobial chemotherapy.

[24]  S. Blanche,et al.  Highly active antiretroviral therapies among HIV-1-infected children in Abidjan, Côte d'Ivoire , 2004, AIDS.

[25]  D. Weber,et al.  A comparison of height and weight velocity as a part of the composite endpoint in pediatric HIV , 2003, AIDS.

[26]  R. de Groot,et al.  Treatment with highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children is associated with a sustained effect on growth. , 2002, Pediatrics.

[27]  L. Molinari,et al.  Growth in human immunodeficiency virus type 1- infected children treated with protease inhibitors , 2001, European Journal of Pediatrics.

[28]  Andrew Thomas,et al.  WinBUGS - A Bayesian modelling framework: Concepts, structure, and extensibility , 2000, Stat. Comput..

[29]  G. Malenga,et al.  The impact of the human immunodeficiency virus type 1 on the management of severe malnutrition in Malawi , 2000, Annals of tropical paediatrics.

[30]  P. Royston,et al.  Regression using fractional polynomials of continuous covariates: parsimonious parametric modelling. , 1994 .

[31]  R. Reed,et al.  NCHS growth curves for children birth-18 years. United States. , 1977, Vital and health statistics. Series 11, Data from the National Health Survey.

[32]  Emiko Masaki,et al.  Antiretroviral therapy for HIV infection in infants and children: towards universal access. Recommendations for a public health approach. , 2007 .

[33]  S. Knobler,et al.  Scaling Up Antiretroviral Therapy in Resource-Limited Settings: Treatment Guidelines for a Public Health Approach , 2005 .

[34]  D. Weber,et al.  Growth patterns reflect response to antiretroviral therapy in HIV-positive infants: potential utility in resource-poor settings. , 2004, AIDS patient care and STDs.