Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells
暂无分享,去创建一个
N. Bundschuh | Adhideb Ghosh | Inseon Kim | Xhem Qabrati | Ori Bar‐Nur | Andrew S. Palmer | Falko Noé | Nicola Bundschuh
[1] E. Malfatti,et al. Thyroid-stimulating hormone receptor signaling restores skeletal muscle stem cell regeneration in rats with muscular dystrophy , 2023, Science Translational Medicine.
[2] Nadezhda T. Doncheva,et al. The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest , 2022, Nucleic Acids Res..
[3] Yao‐Hua Song,et al. Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice. , 2022, Cell reports.
[4] Gene therapy at the crossroads , 2022, Nature Biotechnology.
[5] F. Relaix,et al. The Notch signaling network in muscle stem cells during development, homeostasis, and disease , 2022, Skeletal muscle.
[6] Yanqin Li,et al. Chemical reprogramming of human somatic cells to pluripotent stem cells , 2022, Nature.
[7] J. Kere,et al. CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells , 2022, Stem cell reports.
[8] Ori Bar-Nur,et al. CRISPR/Cas9 editing of directly reprogrammed myogenic progenitors restores dystrophin expression in a mouse model of muscular dystrophy , 2021, Stem cell reports.
[9] Ferdinand von Meyenn,et al. Integrative molecular roadmap for direct conversion of fibroblasts into myocytes and myogenic progenitor cells , 2021, bioRxiv.
[10] Albert E. Almada,et al. Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells , 2021, Genes & development.
[11] Aline Yen Ling Wang,et al. Application of Modified mRNA in Somatic Reprogramming to Pluripotency and Directed Conversion of Cell Fate , 2021, International journal of molecular sciences.
[12] N. Elvassore,et al. MYOD modified mRNA drives direct on-chip programming of human pluripotent stem cells into skeletal myocytes. , 2021, Biochemical and biophysical research communications.
[13] Yuan-Yu Hsueh,et al. Skeletal-muscle regeneration via the chemical induction and expansion of myogenic stem cells in situ or in vitro , 2021, Nature Biomedical Engineering.
[14] K. Patel,et al. Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia , 2021, Experimental physiology.
[15] D. Fu,et al. CCAAT/enhancer‐binding protein beta promotes muscle stem cell quiescence through regulation of quiescence‐associated genes , 2020, Stem cells.
[16] Raphael Gottardo,et al. Integrated analysis of multimodal single-cell data , 2020, Cell.
[17] L. Rubin,et al. Pro-myogenic small molecules revealed by a chemical screen on primary muscle stem cells , 2020, Skeletal muscle.
[18] Howard Y. Chang,et al. Pro-neuronal activity of Myod1 due to promiscuous binding to neuronal genes , 2020, Nature Cell Biology.
[19] George M. Church,et al. Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA , 2020, Science Advances.
[20] Anthony D. Schmitt,et al. Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation. , 2019, Molecular cell.
[21] Fabian J Theis,et al. Generalizing RNA velocity to transient cell states through dynamical modeling , 2019, Nature Biotechnology.
[22] Raphael Gottardo,et al. Orchestrating single-cell analysis with Bioconductor , 2019, Nature Methods.
[23] A. Pasquinelli,et al. Tales of Detailed Poly(A) Tails. , 2019, Trends in cell biology.
[24] Lai Guan Ng,et al. Dimensionality reduction for visualizing single-cell data using UMAP , 2018, Nature Biotechnology.
[25] C. Rudolph,et al. Conversion of adult human fibroblasts into neural precursor cells using chemically modified mRNA , 2018, Heliyon.
[26] Y. Asakura,et al. Cellular localization of the cell cycle inhibitor Cdkn1c controls growth arrest of adult skeletal muscle stem cells , 2018, eLife.
[27] Cole Trapnell,et al. Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. , 2018, Cell systems.
[28] Albert E. Almada,et al. Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors , 2018, Stem cell reports.
[29] Matthew D. Young,et al. SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data , 2018, bioRxiv.
[30] Paul Hoffman,et al. Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.
[31] M. Milone,et al. Clinical use of lentiviral vectors , 2018, Leukemia.
[32] Jia Gu,et al. fastp: an ultra-fast all-in-one FASTQ preprocessor , 2018, bioRxiv.
[33] Kenneth L. Jones,et al. High-efficiency RNA-based reprogramming of human primary fibroblasts , 2018, Nature Communications.
[34] G. Truskey,et al. Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle , 2018, Journal of tissue engineering and regenerative medicine.
[35] M. Ko,et al. Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing , 2018, Scientific Reports.
[36] Hui Zhou,et al. Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development , 2018, Cell Death & Differentiation.
[37] R. Sambasivan,et al. Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells , 2017, bioRxiv.
[38] Lee E. Edsall,et al. Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies , 2017, bioRxiv.
[39] Xiaobing Fu,et al. Small molecules for reprogramming and transdifferentiation , 2017, Cellular and Molecular Life Sciences.
[40] K. Tsuchida,et al. Notch ligands regulate the muscle stem-like state ex vivo but are not sufficient for retaining regenerative capacity , 2017, PloS one.
[41] G. Nolan,et al. High-resolution myogenic lineage mapping by single-cell mass cytometry , 2017, Nature Cell Biology.
[42] M. Ko,et al. Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors , 2017, Scientific Reports.
[43] Aaron T. L. Lun,et al. Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R , 2017, Bioinform..
[44] D. Christiani,et al. Risks Associated With Lentiviral Vector Exposures and Prevention Strategies , 2016, Journal of occupational and environmental medicine.
[45] B. Sullenger,et al. Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts. , 2016, Biochemical and biophysical research communications.
[46] Grace X. Y. Zheng,et al. Massively parallel digital transcriptional profiling of single cells , 2016, Nature Communications.
[47] Yu Zhang,et al. Conversion of human fibroblasts into functional cardiomyocytes by small molecules , 2016, Science.
[48] K. Mamchaoui,et al. Synthetically modified mRNA for efficient and fast human iPS cell generation and direct transdifferentiation to myoblasts. , 2016, Biochemical and biophysical research communications.
[49] F. Saudek,et al. Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors , 2016, Molecular therapy. Nucleic acids.
[50] Lior Pachter,et al. Near-optimal probabilistic RNA-seq quantification , 2016, Nature Biotechnology.
[51] R. Stewart,et al. Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors. , 2016, Cell stem cell.
[52] D. R. Sumner,et al. Chemically modified RNA activated matrices enhance bone regeneration. , 2015, Journal of controlled release : official journal of the Controlled Release Society.
[53] 방석호,et al. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors , 2015 .
[54] Qinying Wang,et al. Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules. , 2015, Cell Stem Cell.
[55] Xiang Li,et al. Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons. , 2015, Cell stem cell.
[56] Hongkui Deng,et al. Direct lineage reprogramming: strategies, mechanisms, and applications. , 2015, Cell stem cell.
[57] Xin Li,et al. A comparison of non-integrating reprogramming methods , 2014, Nature Biotechnology.
[58] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[59] Barbora Malecova,et al. STAT3 signaling controls satellite cell expansion and skeletal muscle repair , 2014, Nature Medicine.
[60] Nicolas A. Dumont,et al. Inhibition of JAK/STAT signaling stimulates adult satellite cell function , 2014, Nature Medicine.
[61] Daniel G. Anderson,et al. Non-viral vectors for gene-based therapy , 2014, Nature Reviews Genetics.
[62] H. Uppal,et al. Direct Reprogramming of Human Fibroblasts to Hepatocyte-Like Cells by Synthetic Modified mRNAs , 2014, PloS one.
[63] Ying Zhang,et al. Direct reprogramming of human fibroblasts to functional and expandable hepatocytes. , 2014, Cell stem cell.
[64] Ronald A. Li,et al. Driving vascular endothelial cell fate of human multipotent Isl1+ heart progenitors with VEGF modified mRNA , 2013, Cell Research.
[65] Ronald A. Li,et al. Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction , 2013, Nature Biotechnology.
[66] L. Hui,et al. Reprogramming fibroblasts into bipotential hepatic stem cells by defined factors. , 2013, Cell stem cell.
[67] H. Deng,et al. Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds , 2013, Science.
[68] Edward Y. Chen,et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.
[69] Derrick J. Rossi,et al. Reprogramming human fibroblasts to pluripotency using modified mRNA , 2013, Nature Protocols.
[70] M. Rudnicki,et al. Genome-wide identification of enhancers in skeletal muscle: the role of MyoD1. , 2012, Genes & development.
[71] M. Rudnicki,et al. Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. , 2012, Molecular cell.
[72] Anatol C. Kreitzer,et al. Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor. , 2012, Cell stem cell.
[73] H. Lehrach,et al. The cytotoxic and immunogenic hurdles associated with non-viral mRNA-mediated reprogramming of human fibroblasts. , 2012, Biomaterials.
[74] Marius Wernig,et al. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells , 2012, Proceedings of the National Academy of Sciences.
[75] Chuanfeng Wu,et al. Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity , 2011, Frontiers of medicine.
[76] Jennifer A. Lawson,et al. Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration. , 2011, Journal of Cell Science.
[77] Naoki Nishishita,et al. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors , 2011, Proceedings of the National Academy of Sciences.
[78] Yasuko Matsumura,et al. A more efficient method to generate integration-free human iPS cells , 2011, Nature Methods.
[79] J. Rosenecker,et al. Expression of therapeutic proteins after delivery of chemically modified mRNA in mice , 2011, Nature Biotechnology.
[80] Alexander Meissner,et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. , 2010, Cell stem cell.
[81] W. L. Ruzzo,et al. Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming. , 2010, Developmental cell.
[82] A. Schambach,et al. Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.
[83] M. Hasegawa,et al. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome , 2009, Proceedings of the Japan Academy. Series B, Physical and biological sciences.
[84] Shahragim Tajbakhsh,et al. Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates. , 2009, Developmental cell.
[85] R. Stewart,et al. Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences , 2009, Science.
[86] Dong Wook Han,et al. Generation of induced pluripotent stem cells using recombinant proteins. , 2009, Cell stem cell.
[87] Rudolf Jaenisch,et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors , 2009, Cell.
[88] J. Utikal,et al. Induced Pluripotent Stem Cells Generated Without Viral Integration , 2008, Science.
[89] Hiroki Kato,et al. Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.
[90] Christine Kinnon,et al. Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients. , 2008, The Journal of clinical investigation.
[91] Jean-Loup Guillaume,et al. Fast unfolding of communities in large networks , 2008, 0803.0476.
[92] S. Yamanaka,et al. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.
[93] Zheng‐gang Liu,et al. JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. , 2006, Free radical biology & medicine.
[94] S. Tapscott,et al. MyoD and the transcriptional control of myogenesis. , 2005, Seminars in cell & developmental biology.
[95] Houping Ni,et al. Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. , 2005, Immunity.
[96] S. Tapscott,et al. MyoD Targets Chromatin Remodeling Complexes to the Myogenin Locus Prior to Forming a Stable DNA-Bound Complex , 2005, Molecular and Cellular Biology.
[97] John J. Andreucci,et al. Composition and Function of AP-1 Transcription Complexes during Muscle Cell Differentiation* , 2002, The Journal of Biological Chemistry.
[98] David W. Anderson,et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[99] Thierry Blu,et al. Least-squares image resizing using finite differences , 2001, IEEE Trans. Image Process..
[100] A. Imbalzano,et al. Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation , 2001, Nature Genetics.
[101] M. Rudnicki,et al. Pax7 Is Required for the Specification of Myogenic Satellite Cells , 2000, Cell.
[102] R. Sorelle. Gene therapy at a crossroads. , 2000, Circulation.
[103] M. G. Cusella De Angelis,et al. High efficiency myogenic conversion of human fibroblasts by adenoviral vector-mediated MyoD gene transfer. An alternative strategy for ex vivo gene therapy of primary myopathies. , 1998, The Journal of clinical investigation.
[104] F. Gage,et al. In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector , 1996, Science.
[105] A. Harel-Bellan,et al. Repression of c-fos promoter by MyoD on muscle cell differentiation , 1993, Nature.
[106] S. Tapscott,et al. Functional antagonism between c-Jun and MyoD proteins: A direct physical association , 1992, Cell.
[107] Y. Jan,et al. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence , 1989, Cell.
[108] S. Tapscott,et al. Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[109] S. Tapscott,et al. MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts. , 1988, Science.
[110] H. Weintraub,et al. Expression of a single transfected cDNA converts fibroblasts to myoblasts , 1987, Cell.
[111] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..