Nucleotide Accumulation Induced in Staphylococcus aureus by Glycine

Strominger, Jack L. (Washington University School of Medicine, St. Louis, Mo.), and Claire H. Birge. Nucleotide accumulation induced in Staphylococcus aureus by glycine. J. Bacteriol. 89:1124–1127. 1965.—High concentrations of glycine induce accumulation of four uridine nucleotides in Staphylococcus aureus. Investigations of their structure suggest that these compounds are uridine diphosphate (UDP)-acetylmuramic acid, UDP-acetylmuramyl-gly-d-glu-l-lys, UDP-acetylmuramyl-l-ala-d-glu-l-lys and UDP-acetylmuramyl-gly-d-glu-l-lys-d-ala-d-ala. The mechanism by which glycine may induce uridine nucleotide accumulation and protoplast formation is discussed.

[1]  J. Strominger,et al.  Biochemical Effects of Novobiocin on Staphylococcus aureus , 1965, Journal of bacteriology.

[2]  E. A. Grula,et al.  Incorporation of D-serine into the cell wall mucopeptide of Micrococcus lysodeikticus. , 1964, Biochemical and biophysical research communications.

[3]  J. Strominger,et al.  Enzymatic Synthesis of the Peptide in Bacterial Uridine Nucleotides I. ENZYMATIC ADDITION OF l-ALANINE, d-GLUTAMIC ACID, AND l-LYSINE , 1962 .

[4]  J. Strominger,et al.  Enzymatic Synthesis of the Peptide in Bacterial Uridine Nucleotides II. ENZYMATIC SYNTHESIS AND ADDITION OF d-ALANYL-d-ALANINE , 1962 .

[5]  L. Henderson,et al.  Hydroxylysine metabolism in Streptococcus faecalis. , 1962, The Journal of biological chemistry.

[6]  Strominger Jl.  Biosynthesis of bacterial cell walls. , 1962 .

[7]  J. Strominger.  Biosynthesis of bacterial cell walls. , 1962, Federation proceedings.

[8]  K. Lark,et al.  Studies on the mechanism by which D-amino acids block cell wall synthesis. , 1961, Biochimica et biophysica acta.

[9]  M. Rubio-Huertos,et al.  MORPHOLOGY AND PATHOGENICITY OF L FORMS OF CLOSTRIDIUM TETANI INDUCED BY GLYCINE , 1960, Annals of the New York Academy of Sciences.

[10]  H. Rogers,et al.  The products of the partial acid hydrolysis of the mucopeptide from cell walls of Micrococcus lysodeikticus. , 1959, Biochemical Journal.

[11]  J. Strominger,et al.  The optical configuration of the alanine residues in a uridine nucleotide and in the cell wall of Staphylococcus aureus. , 1959, Biochimica et Biophysica Acta.

[12]  M. Welsch.  Formation de protoplastes d’Escherichia coli sous l’influence de la glycine et d’autres acides aminés , 1958, Pathobiology.

[13]  J. Strominger.  Microbial uridine-5'-pyrophosphate N-acetylamino sugar compounds. I. Biology of the penicillin-induced accumulation. , 1957, The Journal of biological chemistry.

[14]  J. BOGOJEVIC-DJORDJEVIC.  ‘L Forms’ of Bacteria , 1957, Nature.

[15]  J. Strominger,et al.  A modified colorimetric method for the estimation of N-acetylamino sugars. , 1955, The Journal of biological chemistry.

[16]  P. Zamecnik,et al.  TRANSFORMATION OF BACTERIA INTO L FORMS BY AMINO ACIDS, , 1952, Journal of bacteriology.

[17]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[18]  R. Hall,et al.  A comparison of the degree of lysis by glycine of normal and glycine‐resistant organisms , 1949 .

[19]  P. B. Cowles,et al.  The Use of Glycine in the Disruption of Bacterial Cells. , 1948, Science.