Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: maintenance of tight latency with efficient reactivation upon induction.

[1]  D. Ganem,et al.  Infection of primary human tonsillar lymphoid cells by KSHV reveals frequent but abortive infection of T cells. , 2011, Virology.

[2]  D. Ganem,et al.  Active lytic infection of human primary tonsillar B cells by KSHV and its noncytolytic control by activated CD4+ T cells. , 2011, The Journal of clinical investigation.

[3]  D. Ganem,et al.  The Lytic Transcriptome of Kaposi's Sarcoma-Associated Herpesvirus Reveals Extensive Transcription of Noncoding Regions, Including Regions Antisense to Important Genes , 2010, Journal of Virology.

[4]  D. Ganem.  KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine. , 2010, The Journal of clinical investigation.

[5]  B. Chandran.  Early Events in Kaposi's Sarcoma-Associated Herpesvirus Infection of Target Cells , 2009, Journal of Virology.

[6]  T. Seo,et al.  Centrifugal enhancement of Kaposi's sarcoma-associated virus infection of human endothelial cells in vitro. , 2008, Journal of virological methods.

[7]  L. Hutt-Fletcher.  Epstein-Barr Virus Entry , 2007, Journal of Virology.

[8]  D. Aucoin,et al.  A Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 ORF50 Deletion Mutant Is Defective for Reactivation of Latent Virus and DNA Replication , 2005, Journal of Virology.

[9]  J. Vieira,et al.  Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression. , 2004, Virology.

[10]  D. Ganem,et al.  RBP-J (CSL) Is Essential for Activation of the K14/vGPCR Promoter of Kaposi's Sarcoma-Associated Herpesvirus by the Lytic Switch Protein RTA , 2004, Journal of Virology.

[11]  D. Ganem,et al.  Host Range of Kaposi's Sarcoma-Associated Herpesvirus in Cultured Cells , 2003, Journal of Virology.

[12]  Y. Gwack,et al.  Global Changes in Kaposi's Sarcoma-Associated Virus Gene Expression Patterns following Expression of a Tetracycline-Inducible Rta Transactivator , 2003, Journal of Virology.

[13]  Julia T. Chu,et al.  Rta of the human herpesvirus 8/Kaposi sarcoma-associated herpesvirus up-regulates human interleukin-6 gene expression. , 2002, Blood.

[14]  D. Ganem,et al.  The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway. , 2002, Genes & development.

[15]  D. Ganem,et al.  DNA Binding by Kaposi's Sarcoma-Associated Herpesvirus Lytic Switch Protein Is Necessary for Transcriptional Activation of Two Viral Delayed Early Promoters , 2001, Journal of Virology.

[16]  R. Sun,et al.  Transcription Activation of Polyadenylated Nuclear RNA by Rta in Human Herpesvirus 8/Kaposi's Sarcoma-Associated Herpesvirus , 2001, Journal of Virology.

[17]  M. Corbellino,et al.  Activation of latent Kaposi's sarcoma-associated herpesvirus by demethylation of the promoter of the lytic transactivator , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[18]  B. Chandran,et al.  Activation of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Lytic Replication by Human Cytomegalovirus , 2001, Journal of Virology.

[19]  Jiguo Chen,et al.  Transcriptional Regulation of the Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor Gene , 2000, Journal of Virology.

[20]  J. Arbiser,et al.  Valproic acid induces human herpesvirus 8 lytic gene expression in BCBL-1 cells. , 2000, AIDS.

[21]  J. McCune,et al.  Experimental Transmission of Kaposi's Sarcoma–Associated Herpesvirus (Kshv/Hhv-8) to Scid-Hu Thy/Liv Mice , 1999, The Journal of experimental medicine.

[22]  D. Ganem,et al.  Transcriptional Activation by the Product of Open Reading Frame 50 of Kaposi’s Sarcoma-Associated Herpesvirus Is Required for Lytic Viral Reactivation in B Cells , 1999, Journal of Virology.

[23]  Lijun Wu,et al.  A Complex Translational Program Generates Multiple Novel Proteins from the Latently Expressed Kaposin (K12) Locus of Kaposi’s Sarcoma-Associated Herpesvirus , 1999, Journal of Virology.

[24]  D. Ganem,et al.  Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein. , 1998, Virology.

[25]  R. Sun,et al.  A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[26]  R. Sun,et al.  Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells , 1997, Journal of virology.

[27]  M. McGrath,et al.  Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture , 1996, Nature Medicine.

[28]  E. Rubinstein,et al.  Kaposi's sarcoma in immunosuppression possibly the result of a dual viral infection , 1990, Cancer.

[29]  M. Kozak.  An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs. , 1987, Nucleic acids research.

[30]  M. Kozak.  Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes , 1986, Cell.

[31]  M. Kozak,et al.  Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo , 1984, Nature.

[32]  J. Bertino,et al.  Quantitation of dihydrofolate reductase in individual parental and methotrexate-resistant murine cells. Use of a fluorescence activated cell sorter. , 1978, The Journal of biological chemistry.

[33]  J. Bertino,et al.  Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells. , 1978, The Journal of biological chemistry.

[34]  J. Bertino,et al.  Amplification of dihydrofolate reductase genes in methotrexate-resistant cultured mouse cells. , 1978, Cold Spring Harbor symposia on quantitative biology.