Assessment of Left Ventricular Mass by Cardiovascular Magnetic Resonance

Left ventricular hypertrophy is associated with significant excess mortality and morbidity. The study and treatment of this condition, in particular the prognostic implications of changes in left ventricular mass, require an accurate, safe, and reproducible method of measurement. Cardiovascular magnetic resonance is a suitable tool for this purpose, and this review assesses the technique in comparison with others and examines the clinical and research implications of the improved reproducibility.

[1]  J. Hayano,et al.  Influence of Body Composition on Electrocardiographic Identification of Left Ventricular Hypertrophy in Adolescents , 1999, Cardiology.

[2]  S. Sasayama,et al.  Single breath-hold left ventricular volume measurement by 0.3-sec turbo fast low-angle shot MR imaging. , 1999, AJR. American journal of roentgenology.

[3]  W. Haskell,et al.  Evaluation of the Echocardiogram as an Epidemiologic Tool in an Asymptomatic Population , 1979, Circulation.

[4]  G. Chatellier,et al.  Determination of left ventricular mass with electron beam computed tomography in deformed, hypertrophic human hearts. , 1994, European heart journal.

[5]  C. Gaudio,et al.  Benazepril causes in hypertension a greater reduction in left ventricular mass than does nitrendipine: a randomized study using magnetic resonance imaging. , 1998, Journal of cardiovascular pharmacology.

[6]  M. Kronenberg,et al.  Reproducibility of left ventricular mass measurements by two-dimensional and M-mode echocardiography. , 1989, Journal of the American College of Cardiology.

[7]  P. Gosse,et al.  Is echocardiography an adequate method to evaluate left ventricular hypertrophy regression? , 1990, European heart journal.

[8]  N. Reichek,et al.  Anatomic Validation of Left Ventricular Mass Estimates from Clinical Two‐dimensional Echocardiography: Initial Results , 1983, Circulation.

[9]  L. Boxt,et al.  Comparison of three-dimensional echocardiographic assessment of volume, mass, and function in children with functionally single left ventricles with two-dimensional echocardiography and magnetic resonance imaging. , 1997, The American journal of cardiology.

[10]  D. Pennell,et al.  Left ventricular quantification in heart failure by cardiovascular MR using prospective respiratory navigator gating: Comparison with breath‐hold acquisition , 2000, Journal of magnetic resonance imaging : JMRI.

[11]  R Beyar,et al.  Determination of left ventricular mass by magnetic resonance imaging in hearts deformed by acute infarction. , 1989, Circulation.

[12]  S. Yusuf,et al.  Reduction of Cardiovascular Risk by Regression of Electrocardiographic Markers of Left Ventricular Hypertrophy by the Angiotensin-Converting Enzyme Inhibitor Ramipril , 2001, Circulation.

[13]  D. Pennell,et al.  Treatment of claustrophobia for cardiovascular magnetic resonance: use and effectiveness of mild sedation. , 2000, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[14]  D E Manyari,et al.  Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. , 1990, The New England journal of medicine.

[15]  C. Higgins,et al.  Measurement of canine left ventricular mass by using MR imaging. , 1987, AJR. American journal of roentgenology.

[16]  E. Kaplinsky.  Significance of left ventricular hypertrophy in cardiovascular morbidity and mortality , 1994, Cardiovascular Drugs and Therapy.

[17]  H. S. Klopfenstein,et al.  Left ventricular mass in the elderly. The Cardiovascular Health Study. , 1997, Hypertension.

[18]  P. Rautaharju,et al.  Body Position, Electrode Level, and Respiration Effects on the Frank Lead Electrocardiogram , 1976, Circulation.

[19]  U. Heidland,et al.  Left Ventricular Muscle Mass and Elevated Heart Rate Are Associated With Coronary Plaque Disruption , 2001, Circulation.

[20]  K. Murata,et al.  Evaluation of left ventricular mass: comparison of ultrafast computed tomography, magnetic resonance imaging, and contrast left ventriculography. , 1993, American heart journal.

[21]  R W Parkey,et al.  Estimation of human myocardial mass with MR imaging. , 1988, Radiology.

[22]  Maurice Sokolow,et al.  American Heart Journal , 2001 .

[23]  E. H. Estes,et al.  A point-score system for the ECG diagnosis of left ventricular hypertrophy. , 1968, American heart journal.

[24]  D S Berman,et al.  Noninvasive quantification of left ventricular myocardial mass by gated proton nuclear magnetic resonance imaging. , 1987, Journal of the American College of Cardiology.

[25]  GiuseppeSchillaci,et al.  Prognostic Significance of Serial Changes in Left Ventricular Mass in Essential Hypertension , 1998 .

[26]  D. King,et al.  Serial assessment of left ventricular mass regression by 3D echocardiography requires three-fold fewer subjects compared to conventional 1D and 2D echocardiography , 1996 .

[27]  M. Sokolow,et al.  The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads. , 1949, American heart journal.

[28]  N. Reichek,et al.  Left Ventricular Hypertrophy: Relationship of Anatomic, Echocardiographic and Electrocardiographic Findings , 1981, Circulation.

[29]  R. C. Scott,et al.  A Critical Appraisal of the Electrocardiographic Criteria for the Diagnosis of Left Ventricular Hypertrophy , 1969, Circulation.

[30]  S. M. Collins,et al.  Determination of left ventricular mass in dogs with rapid-acquisition cardiac computed tomographic scanning. , 1985, Circulation.

[31]  M. Wong,et al.  Reproducibility of left ventricular internal dimensions with M mode echocardiography: effects of heart size, body position and transducer angulation. , 1981, The American journal of cardiology.

[32]  J. Gottdiener,et al.  Should echocardiography be performed to assess effects of antihypertensive therapy? Test-retest reliability of echocardiography for measurement of left ventricular mass and function. , 1995, Journal of the American College of Cardiology.

[33]  P. Guéret,et al.  Ramipril-induced regression of left ventricular hypertrophy in treated hypertensive individuals. HYCAR Study Group. , 1995, Hypertension.

[34]  J. Ghali,et al.  The Prognostic Role of Left Ventricular Hypertrophy in Patients with or without Coronary Artery Disease , 1992, Annals of Internal Medicine.

[35]  R. Devereux,et al.  Reliability of echocardiographic assessment of left ventricular structure and function: the PRESERVE study. Prospective Randomized Study Evaluating Regression of Ventricular Enlargement. , 1999, Journal of the American College of Cardiology.

[36]  J C Ehrhardt,et al.  Measurement of left ventricular mass in vivo using gated nuclear magnetic resonance imaging. , 1986, Journal of the American College of Cardiology.

[37]  J. Schwartz,et al.  Association of carotid atherosclerosis and left ventricular hypertrophy. , 1995, Journal of the American College of Cardiology.

[38]  S. Humphries,et al.  Bradykinin B2BKR receptor polymorphism and left-ventricular growth response , 2001, The Lancet.

[39]  W. Kannel,et al.  Left ventricular hypertrophy and mortality--results from the Framingham Study. , 1992, Cardiology.

[40]  E Tomei,et al.  Normal left ventricular dimensions and function: interstudy reproducibility of measurements with cine MR imaging. , 1990, Radiology.

[41]  F J Ten Cate,et al.  Measurements and day-to-day variabilities of left ventricular volumes and ejection fraction by three-dimensional echocardiography and comparison with magnetic resonance imaging. , 1998, The American journal of cardiology.

[42]  R. Pini,et al.  Differential effects of angiotensin converting enzyme inhibition and diuretic therapy on reductions in ambulatory blood pressure, left ventricular mass, and vascular hypertrophy. , 1998, American journal of hypertension.

[43]  B. Massie,et al.  Hypertensive Heart Disease: The Critical Role of Left Ventricular Hypertrophy , 1989, Journal of cardiovascular pharmacology.

[44]  A E Stillman,et al.  Rapid, accurate and simultaneous noninvasive assessment of right and left ventricular mass with nuclear magnetic resonance imaging using the snapshot gradient method. , 1992, Journal of the American College of Cardiology.

[45]  R W Parkey,et al.  In vivo measurement of myocardial mass using nuclear magnetic resonance imaging. , 1986, Journal of the American College of Cardiology.

[46]  N. Schiller,et al.  Reproducibility of quantitative two-dimensional echocardiography. , 1988, American heart journal.

[47]  J. Heo,et al.  Dipyridamole cardiac imaging. , 1988, American heart journal.

[48]  R. Devereux,et al.  Reproducibility of Echocardiographic Left Ventricular Measurements , 1987, Hypertension.

[49]  R. Günther,et al.  Transesophageal 3-dimensional echocardiography: in vivo determination of left ventricular mass in comparison with magnetic resonance imaging. , 2000, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[50]  G. Reboldi,et al.  Prognostic significance of serial changes in left ventricular mass in essential hypertension. , 1998, Circulation.

[51]  J. Laragh,et al.  Cost‐Effectiveness of Echocardiography and Electrocardiography for Detection of Left Ventricular Hypertrophy in Patients with Systemic Hypertension , 1987, Hypertension.

[52]  D J Pennell,et al.  Reduction in sample size for studies of remodeling in heart failure by the use of cardiovascular magnetic resonance. , 2000, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[53]  J. Reiber,et al.  Angiotensin-converting enzyme inhibitor therapy affects left ventricular mass in patients with ejection fraction > 40% after acute myocardial infarction. , 1997, Journal of the American College of Cardiology.

[54]  D. King,et al.  Freehand three-dimensional echocardiography for measurement of left ventricular mass: in vivo anatomic validation using explanted human hearts. , 1997, Journal of the American College of Cardiology.

[55]  R S Meltzer,et al.  Accuracy of echocardiography versus electrocardiography in detecting left ventricular hypertrophy: comparison with postmortem mass measurements. , 1983, Journal of the American College of Cardiology.

[56]  D. Levy,et al.  Prognostic implications of baseline electrocardiographic features and their serial changes in subjects with left ventricular hypertrophy. , 1994, Circulation.

[57]  K. Pennert,et al.  Reversal of left ventricular hypertrophy in hypertensive patients. A metaanalysis of 109 treatment studies. , 1992, American journal of hypertension.

[58]  J. Gottdiener,et al.  Magnetic resonance imaging compared to echocardiography to assess left ventricular mass in the hypertensive patient. , 1995, American journal of hypertension.

[59]  N. Reichek,et al.  Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. , 1986, The American journal of cardiology.

[60]  D. Pennell,et al.  Left Ventricular Hypertrophy With Exercise and ACE Gene Insertion/Deletion Polymorphism: A Randomized Controlled Trial With Losartan , 2001, Circulation.

[61]  R Hoekema,et al.  Interindividual variability of multilead electrocardiographic recordings: influence of heart position. , 1999, Journal of electrocardiology.

[62]  D. King,et al.  Three-dimensional echocardiography: in vitro and in vivo validation of left ventricular mass and comparison with conventional echocardiographic methods. , 1994, Journal of the American College of Cardiology.

[63]  C. Higgins,et al.  Interstudy reproducibility of dimensional and functional measurements between cine magnetic resonance studies in the morphologically abnormal left ventricle. , 1990, American heart journal.

[64]  B Kastler,et al.  Inter-study variability in left ventricular mass measurement. Comparison between M-mode echography and MRI. , 1992, European heart journal.

[65]  N Reichek,et al.  Echocardiographic Determination of Left Ventricular Mass in Man: Anatomic Validation of the Method , 1977, Circulation.

[66]  J. Rumberger,et al.  Reproducibility of right and left ventricular volume measurements by electron-beam CT in patients with congestive heart failure , 1998, The International Journal of Cardiac Imaging.