Pharmacogenetic profiling via genome sequencing in children with medical complexity

[1]  Y. Akkari,et al.  Noninvasive prenatal screening (NIPS) for fetal chromosome abnormalities in a general-risk population: An evidence-based clinical guideline of the American College of Medical Genetics and Genomics (ACMG). , 2022, Genetics in medicine : official journal of the American College of Medical Genetics.

[2]  R. V. van Schaik,et al.  The Impact of Pharmacogenetics on Pharmacokinetics and Pharmacodynamics in Neonates and Infants: A Systematic Review , 2022, Pharmacogenomics and personalized medicine.

[3]  Matthew S. Lebo,et al.  Automated Pharmacogenomic Reports for Clinical Genome Sequencing. , 2022, The Journal of molecular diagnostics : JMD.

[4]  N. Lennon,et al.  Whole genome sequencing as an investigational device for return of hereditary disease risk and pharmacogenomic results as part of the All of Us Research Program , 2021, medRxiv.

[5]  S. Scherer,et al.  Genome sequencing as a diagnostic test , 2021, Canadian Medical Association Journal.

[6]  P. Gill,et al.  Research priorities for children with neurological impairment and medical complexity in high‐income countries , 2021, Developmental medicine and child neurology.

[7]  J. Feinstein,et al.  Complexity of Medication Regimens for Children With Neurological Impairment , 2021, JAMA network open.

[8]  R. Myers,et al.  A study of elective genome sequencing and pharmacogenetic testing in an unselected population , 2021, Molecular genetics & genomic medicine.

[9]  M. Whirl‐Carrillo,et al.  An Evidence‐Based Framework for Evaluating Pharmacogenomics Knowledge for Personalized Medicine , 2021, Clinical pharmacology and therapeutics.

[10]  Danny E Miller,et al.  Exome and genome sequencing for pediatric patients with congenital anomalies or intellectual disability: an evidence-based clinical guideline of the American College of Medical Genetics and Genomics (ACMG) , 2021, Genetics in Medicine.

[11]  Christopher L Farrell,et al.  The impact of pharmacogenetic testing in patients exposed to polypharmacy: a scoping review , 2021, The Pharmacogenomics Journal.

[12]  T. Paton,et al.  Assessment of the Implementation of Pharmacogenomic Testing in a Pediatric Tertiary Care Setting , 2021, JAMA network open.

[13]  Andrew G. Sharo,et al.  Opportunities and challenges for the computational interpretation of rare variation in clinically important genes , 2021, American journal of human genetics.

[14]  Ryan J Coller,et al.  Timing of Co-occurring Chronic Conditions in Children With Neurologic Impairment , 2021, Pediatrics.

[15]  V. Jobanputra,et al.  Clinical utility of genomic sequencing: a measurement toolkit , 2020, npj Genomic Medicine.

[16]  Leigh Anne Tang,et al.  Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients , 2020, JAMA network open.

[17]  J. Feinstein,et al.  Parent-Reported Symptoms and Medications Used Among Children With Severe Neurological Impairment , 2020, JAMA network open.

[18]  K. Huth,et al.  Medication safety for children with medical complexity. , 2020, Paediatrics & child health.

[19]  S. Scherer,et al.  Genome Sequencing as a Diagnostic Test in Children With Unexplained Medical Complexity , 2020, JAMA network open.

[20]  Julia M. Barbarino,et al.  Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing , 2020, Clinical pharmacology and therapeutics.

[21]  Scott Hazelhurst,et al.  A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: a focus on CYP2D6 genotyping , 2020, npj Genomic Medicine.

[22]  D. Nickerson,et al.  Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences , 2019, Clinical pharmacology and therapeutics.

[23]  J. Belmont,et al.  Case for genome sequencing in infants and children with rare, undiagnosed or genetic diseases , 2019, Journal of Medical Genetics.

[24]  S. Bolen,et al.  Variation of the prevalence of pediatric polypharmacy: A scoping review , 2019, Pharmacoepidemiology and drug safety.

[25]  J. Feinstein,et al.  Choosing medications wisely: Is it time to address paediatric polypharmacy? , 2019, Paediatrics & child health.

[26]  T. Lewis,et al.  Pharmacogenomics and implementation of precision therapeutics in the neonatal ICU: a new frontier? , 2018, Pharmacogenomics.

[27]  S. Ito,et al.  Professional opportunity for pharmacists to integrate pharmacogenomics in medication therapy , 2018, Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC.

[28]  Daniele Merico,et al.  The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants , 2018, Canadian Medical Association Journal.

[29]  Daniele Merico,et al.  Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test , 2017, Genetics in Medicine.

[30]  Stephen H. Bell,et al.  A ?scoping review. , 2018, Sexual health.

[31]  S. Scherer,et al.  Genome sequencing as a platform for pharmacogenetic genotyping: a pediatric cohort study , 2017, npj Genomic Medicine.

[32]  R. Cohn,et al.  Genetic Testing among Children in a Complex Care Program , 2017, Children.

[33]  S. Kingsnorth,et al.  Children with medical complexity: a scoping review of interventions to support caregiver stress , 2017, Child: care, health and development.

[34]  T. Dewan,et al.  Children with medical complexity in Canada. , 2013, Paediatrics & child health.

[35]  Eyal Cohen,et al.  Patterns and Costs of Health Care Use of Children With Medical Complexity , 2012, Pediatrics.

[36]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[37]  Eyal Cohen,et al.  A national profile of caregiver challenges among more medically complex children with special health care needs. , 2011, Archives of pediatrics & adolescent medicine.

[38]  T. Klein,et al.  CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network , 2011, Clinical pharmacology and therapeutics.