Analysis of the transcriptional program induced by Raf in epithelial cells

[1]  H. Lehrach,et al.  Induction of putative tumor-suppressing genes in Rat-1 fibroblasts by oncogenic Raf-1 as evidenced by robot-assisted complex hybridization , 2000, Journal of Molecular Medicine.

[2]  C. Der,et al.  Understanding Ras: 'it ain't over 'til it's over'. , 2000, Trends in cell biology.

[3]  J. Pouysségur,et al.  The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal. , 2000, Molecular biology of the cell.

[4]  S. Yonehara,et al.  Oncogenic K-Ras and Basic Fibroblast Growth Factor Prevent FAS-Mediated Apoptosis in Fibroblasts through Activation of Mitogen-Activated Protein Kinase , 2000, The Journal of cell biology.

[5]  J. Blenis,et al.  Rsk1 mediates a MEK–MAP kinase cell survival signal , 2000, Current Biology.

[6]  L. Coussens,et al.  Extrinsic regulators of epithelial tumor progression: metalloproteinases. , 2000, Current opinion in genetics & development.

[7]  Johannes Zuber,et al.  A genome-wide survey of RAS transformation targets , 2000, Nature Genetics.

[8]  J. Folkman,et al.  The Hemostatic System as a Regulator of Angiogenesis* , 2000, The Journal of Biological Chemistry.

[9]  H. Ruan,et al.  p90RSK Blocks Bad-mediated Cell Death via a Protein Kinase C-dependent Pathway* , 1999, The Journal of Biological Chemistry.

[10]  Y. Sun,et al.  Essential role of biliary glycoprotein (CD66a) in morphogenesis of the human mammary epithelial cell line MCF10F. , 1999, Journal of cell science.

[11]  S. R. Datta,et al.  Cellular survival: a play in three Akts. , 1999, Genes & development.

[12]  S. R. Datta,et al.  Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. , 1999, Science.

[13]  J. Downward,et al.  Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis , 1999, Current Biology.

[14]  G. Cooper,et al.  B-Raf Inhibits Programmed Cell Death Downstream of Cytochrome c Release from Mitochondria by Activating the MEK/Erk Pathway , 1999, Molecular and Cellular Biology.

[15]  Andrius Kazlauskas,et al.  Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes , 1999, Cell.

[16]  J. Downward How BAD phosphorylation is good for survival , 1999, Nature Cell Biology.

[17]  R. Montesano,et al.  Constitutively Active Mitogen-activated Protein Kinase Kinase Mek1 Disrupts Morphogenesis and Induces an Invasive Phenotype in Madin-darby Canine Kidney Epithelial Cells 1 , 1999 .

[18]  S. Cook,et al.  The Repertoire of Fos and Jun Proteins Expressed during the G1 Phase of the Cell Cycle Is Determined by the Duration of Mitogen-Activated Protein Kinase Activation , 1999, Molecular and Cellular Biology.

[19]  M. Roussel,et al.  Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. , 1998, Genes & development.

[20]  A. Klippel,et al.  Activation of Phosphatidylinositol 3-Kinase Is Sufficient for Cell Cycle Entry and Promotes Cellular Changes Characteristic of Oncogenic Transformation , 1998, Molecular and Cellular Biology.

[21]  R. Bicknell,et al.  Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis. , 1998, The Biochemical journal.

[22]  J. Downward,et al.  Phosphoinositide 3-Kinase Induces Scattering and Tubulogenesis in Epithelial Cells through a Novel Pathway* , 1998, The Journal of Biological Chemistry.

[23]  J Downward,et al.  Ras signalling and apoptosis. , 1998, Current opinion in genetics & development.

[24]  L. Wodicka,et al.  Genome-wide expression monitoring in Saccharomyces cerevisiae , 1997, Nature Biotechnology.

[25]  M. Schwartz,et al.  Growth factor activation of MAP kinase requires cell adhesion , 1997, The EMBO journal.

[26]  A Sewing,et al.  High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1 , 1997, Molecular and cellular biology.

[27]  M. McMahon,et al.  Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1 , 1997, Oncogene.

[28]  Asim Khwaja,et al.  Matrix adhesion and Ras transformation both activate a phosphoinositide 3‐OH kinase and protein kinase B/Akt cellular survival pathway , 1997, The EMBO journal.

[29]  U. Rodeck,et al.  Regulation of Bcl-xL expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[30]  P. Warne,et al.  Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras , 1997, Cell.

[31]  Michael C. Ostrowski,et al.  Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1 , 1997, Molecular and cellular biology.

[32]  D. Hanahan,et al.  Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis , 1996, Cell.

[33]  R. Treisman,et al.  Regulation of transcription by MAP kinase cascades. , 1996, Current opinion in cell biology.

[34]  C. Albanese,et al.  Transforming p21ras Mutants and c-Ets-2 Activate the Cyclin D1 Promoter through Distinguishable Regions (*) , 1995, The Journal of Biological Chemistry.

[35]  J. Abraham,et al.  Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes. , 1995, Genes & development.

[36]  S. Krajewski,et al.  Apoptosis regulation by interaction of Bcl-2 protein and Raf-1 kinase. , 1994, Oncogene.

[37]  R. Hipskind,et al.  Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo , 1994, Molecular and cellular biology.

[38]  S. Frisch,et al.  Disruption of epithelial cell-matrix interactions induces apoptosis , 1994, The Journal of cell biology.

[39]  J. Russo,et al.  Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. , 1990, Cancer research.

[40]  Masui,et al.  Transforming growth factor-alpha expression is enhanced in human mammary epithelial cells transformed by an activated c-Ha-ras protooncogene but not by the c-neu protooncogene, and overexpression of the transforming growth factor-alpha complementary DNA leads to transformation. , 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[41]  J. L. Bos,et al.  ras oncogenes in human cancer: a review. , 1989, Cancer research.

[42]  G. Todaro,et al.  Growth factors from murine sarcoma virus-transformed cells. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[43]  S. Yonehara,et al.  Oncogenic KRas and Basic Fibroblast Growth Factor Prevent Fas-mediated Apoptosis in Fibroblasts through Activation of Mitogen-activated Protein Kinase , 2000 .

[44]  S. P. Fodor,et al.  High density synthetic oligonucleotide arrays , 1999, Nature Genetics.

[45]  D. Botstein,et al.  The transcriptional program in the response of human fibroblasts to serum. , 1999, Science.

[46]  D. Lockhart,et al.  Expression monitoring by hybridization to high-density oligonucleotide arrays , 1996, Nature Biotechnology.

[47]  C. Marshall Ras effectors. , 1996, Current opinion in cell biology.

[48]  I. Rabinovitz,et al.  The integrin alpha 6 beta 4 and the biology of carcinoma. , 1996, Biochemistry and cell biology = Biochimie et biologie cellulaire.