Fine needle aspiration biopsy in the oral cavity and head and neck region.

The objective of the current study was to evaluate the sensitivity, specificity and accuracy of fine needle aspiration biopsy (FNAB) of submucous nodules from the oral cavity and head and neck region as an auxiliary diagnostic tool. Fifty patients with nodule lesions in the oral cavity and the head and neck region were selected. All of them were submitted to FNAB and to either incisional or excisional biopsy. The diagnoses from the FNABs were compared with the biopsy diagnosis as the gold standard. All the cases of FNAB were analyzed by a single oral pathologist prior to the biopsy diagnosis. The results showed that the sensitivity of FNAB was 75%, its specificity was 96% and its accuracy was 58.8%. The false positive and false negative rates were 6.7% and 13.3%, respectively. The positive predictive value was 86% and the negative predictive value was 93%. The inconclusive rate was 16/50. FNAB displayed a high success rate for identifying both malignant and benign lesions, but a low accuracy for making a final diagnosis.

[1]  H. Saleh,et al.  Value of fine‐needle aspiration biopsy in initial evaluation of floor of the mouth masses: Report of a case of low‐grade mucoepidermoid carcinoma , 2009, Diagnostic cytopathology.

[2]  C. Godballe,et al.  Value of fine‐needle aspiration biopsy of salivary gland lesions , 2009, Head & neck.

[3]  J. Bakshi,et al.  Fine needle aspiration cytology in a case of fibrous dysplasia of jaw , 2009, Diagnostic cytopathology.

[4]  B. Naini,et al.  A correlation study of diagnostic fine‐needle aspiration with histologic diagnosis in cystic neck lesions , 2009, Diagnostic cytopathology.

[5]  J. Carrillo,et al.  Diagnostic accuracy of fine needle aspiration biopsy in preoperative diagnosis of patients with parotid gland masses , 2009, Journal of surgical oncology.

[6]  K. Mishra,et al.  Cytologic Diagnosis in Benign Odontogenic Tumor with Abundant Calcification , 2009, Acta Cytologica.

[7]  S. Anne,et al.  Fine needle aspiration biopsy: role in diagnosis of pediatric head and neck masses. , 2008, International journal of pediatric otorhinolaryngology.

[8]  H. Saleh,et al.  Fine needle aspiration biopsy of intraoral and oropharyngeal mass lesions , 2008, CytoJournal.

[9]  R. Laucirica,et al.  Clinical significance of cultures collected from fine‐needle aspiration biopsy , 2008, Diagnostic cytopathology.

[10]  D. E. da Cruz Perez,et al.  Fine needle aspiration cytology as an additional tool in the diagnosis of odontogenic keratocyst , 2007, Cytopathology : official journal of the British Society for Clinical Cytology.

[11]  B. Florentine,et al.  The reliability of fine‐needle aspiration biopsy as the initial diagnostic procedure for palpable masses , 2006, Cancer.

[12]  J. Jacobs,et al.  Histopathologic and Cytopathologic Diagnostic Discrepancies in Head and Neck Region: Pitfalls, Causes, and Preventive Strategies , 2006, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[13]  J. Shah,et al.  Fine-needle aspiration biopsy of salivary gland lesions in a selected patient population. , 2004, Archives of otolaryngology--head & neck surgery.

[14]  Tze-Wey Loong,et al.  Understanding sensitivity and specificity with the right side of the brain , 2003, BMJ : British Medical Journal.

[15]  R. Amedee,et al.  Fine‐Needle Aspiration Biopsy , 2001, The Laryngoscope.

[16]  J. Safneck,et al.  Fixation Techniques for Fine Needle Aspiration Biopsy Smears Prepared Off Site , 2001, Acta Cytologica.

[17]  R. Martín-Granizo,et al.  Fine needle aspiration biopsy (FNAB) for lesions of the salivary glands. , 2000, The British journal of oral & maxillofacial surgery.

[18]  B. Ljung,et al.  Transmucosal Fine‐Needle Aspiration Diagnosis of Intraoral and Intrapharyngeal Lesions , 1999, The Laryngoscope.

[19]  D. Dabbs.  The surgical pathologist's approach to fine needle aspiration. , 1998, Clinics in laboratory medicine.

[20]  F. Fulciniti,et al.  Accuracy of fine needle aspiration biopsy in head and neck tumors. , 1997, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[21]  H. Hughes,et al.  Virus Persistence , 1982 .