Biodiesel production from oleaginous microorganisms

High energy prices, energy and environment security, concerns about petroleum supplies are drawing considerable attention to find a renewable biofuels. Biodiesel, a mixture of fatty acid methyl esters (FAMEs) derived from animal fats or vegetable oils, is rapidly moving towards the mainstream as an alternative source of energy. However, biodiesel derived from conventional petrol or from oilseeds or animal fat cannot meet realistic need, and can only be used for a small fraction of existing demand for transport fuels. In addition, expensive large acreages for sufficient production of oilseed crops or cost to feed animals are needed for raw oil production. Therefore, oleaginous microorganisms are available for substituting conventional oil in biodiesel production. Most of the oleaginous microorganisms like microalgae, bacillus, fungi and yeast are all available for biodiesel production. Regulation mechanism of oil accumulation in microorganism and approach of making microbial diesel economically competitive with petrodiesel are discussed in this review.

[1]  J. Harwood,et al.  Lipids and lipid metabolism in eukaryotic algae. , 2006, Progress in lipid research.

[2]  Colin Ratledge,et al.  Fatty acid biosynthesis in microorganisms being used for Single Cell Oil production. , 2004, Biochimie.

[3]  Lewis M. Brown,et al.  Genetic Engineering Approaches for Enhanced Production of Biodiesel Fuel from Microalgae , 1994 .

[4]  A. Steinbüchel,et al.  Neutral Lipid Biosynthesis in Engineered Escherichia coli: Jojoba Oil-Like Wax Esters and Fatty Acid Butyl Esters , 2006, Applied and Environmental Microbiology.

[5]  Govinda R. Timilsina,et al.  Second-Generation Biofuels: Economics and Policies , 2010 .

[6]  J. Harwood Recent advances in the biosynthesis of plant fatty acids. , 1996, Biochimica et biophysica acta.

[7]  Fengwu Bai,et al.  High-density cultivation of oleaginous yeast Rhodosporidium toruloides Y4 in fed-batch culture , 2007 .

[8]  K. Liukkonen,et al.  Temperature adaptation in yeasts: the role of fatty acids. , 1990, Journal of general microbiology.

[9]  H. Iwamoto,et al.  Industrial Production of Microalgal Cell‐Mass and Secondary Products ‐ Major Industrial Species: Chlorella , 2007 .

[10]  Yusuf Chisti,et al.  Shear stress tolerance and biochemical characterization of Phaeodactylum tricornutum in quasi steady-state continuous culture in outdoor photobioreactors. , 2003 .

[11]  José Luis Guil-Guerrero,et al.  Functional properties of the biomass of three microalgal species , 2004 .

[12]  A. Steinbüchel,et al.  A Novel Bifunctional Wax Ester Synthase/Acyl-CoA:Diacylglycerol Acyltransferase Mediates Wax Ester and Triacylglycerol Biosynthesis inAcinetobacter calcoaceticus ADP1* , 2003, The Journal of Biological Chemistry.

[13]  Y. Chisti Biodiesel from microalgae. , 2007, Biotechnology advances.

[14]  Emily E. Peacock,et al.  Biodegradation and environmental behavior of biodiesel mixtures in the sea: An initial study. , 2007, Marine pollution bulletin.

[15]  O. Pulz,et al.  Valuable products from biotechnology of microalgae , 2004, Applied Microbiology and Biotechnology.

[16]  H. Harms,et al.  Impact of membrane fatty acid composition on the uncoupling sensitivity of the energy conservation of Comamonas testosteroni ATCC 17454 , 2006, Applied Microbiology and Biotechnology.

[17]  William H. Kemp,et al.  Biodiesel Basics and Beyond: A Comprehensive Guide to Production and Use for the Home and Farm , 2006 .

[18]  F. Kargı,et al.  Bio-hydrogen production from waste materials , 2006 .

[19]  A. Grossman,et al.  Trophic Conversion of an Obligate Photoautotrophic Organism Through Metabolic Engineering , 2001, Science.

[20]  R. Andersen,et al.  Diversity of eukaryotic algae , 1992, Biodiversity & Conservation.

[21]  C. Largeau,et al.  Botryococcus braunii: a rich source for hydrocarbons and related ether lipids , 2005, Applied Microbiology and Biotechnology.

[22]  Greg Pahl,et al.  Biodiesel: Growing a New Energy Economy , 2005 .

[23]  S. Papanikolaou,et al.  Single cell oil production by Yarrowia lipolytica growing on an industrial derivative of animal fat in batch cultures , 2002, Applied Microbiology and Biotechnology.

[24]  X. Miao,et al.  Biodiesel production from heterotrophic microalgal oil. , 2006, Bioresource technology.

[25]  S. Takeno,et al.  Transformation of oil-producing fungus, Mortierella alpina 1S-4, using Zeocin, and application to arachidonic acid production. , 2005, Journal of bioscience and bioengineering.

[26]  A. Melis,et al.  Green alga hydrogen production: progress, challenges and prospects , 2002 .

[27]  Seraphim Papanikolaou,et al.  Single cell oil (SCO) production by Mortierella isabellina grown on high-sugar content media. , 2004, Bioresource technology.

[28]  C. Ratledge,et al.  Single cell oils--have they a biotechnological future? , 1993, Trends in biotechnology.

[29]  G. Goma,et al.  Influence of nitrogen and iron limitations on lipid production by Cryptococcus curvatus grown in batch and fed-batch culture , 1996 .

[30]  A. Dijkstra Revisiting the formation of trans isomers during partial hydrogenation of triacylglycerol oils , 2006 .

[31]  C. T. Evans,et al.  Influence of Nitrogen Metabolism on Lipid Accumulation by Rhodosporidium toruloides CBS 14 , 1984 .

[32]  Michael Seibert,et al.  Continuous hydrogen photoproduction by Chlamydomonas reinhardtii , 2005, Applied biochemistry and biotechnology.

[33]  Y. Chisti,et al.  Botryococcus braunii: A Renewable Source of Hydrocarbons and Other Chemicals , 2002, Critical reviews in biotechnology.

[34]  S. Papanikolaou,et al.  Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple‐limited media , 2004, Journal of applied microbiology.

[35]  A. Steinbüchel,et al.  Triacylglycerols in prokaryotic microorganisms , 2002, Applied Microbiology and Biotechnology.

[36]  R. Srinivasan,et al.  Lipid and Fatty Acid Composition of Selected Fungi Grown on Whey Medium , 1984 .

[37]  S. Polasky,et al.  Environmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[38]  Yan-Hui Liu,et al.  Escherichia coli acetyl-coenzyme A carboxylase: characterization and development of a high-throughput assay. , 2006, Analytical biochemistry.

[39]  C. Ratledge,et al.  Regulation of lipid accumulation in oleaginous micro-organisms. , 2002, Biochemical Society transactions.

[40]  A. Sree,et al.  Screening of bacterial associates of marine sponges for single cell oil and PUFA , 2005, Letters in applied microbiology.

[41]  Rainer Kalscheuer,et al.  Synthesis of Novel Lipids in Saccharomyces cerevisiae by Heterologous Expression of an Unspecific Bacterial Acyltransferase , 2004, Applied and Environmental Microbiology.

[42]  A. Steinbüchel,et al.  Bacterial and other biological systems for polyester production. , 1998, Trends in biotechnology.

[43]  Rainer Kalscheuer,et al.  Microdiesel: Escherichia coli engineered for fuel production. , 2006, Microbiology.

[44]  O. Suzuki,et al.  Production of arachidonic acid by filamentous fungus, Mortierella alliacea strain YN-15 , 2001 .

[45]  E. Belarbi,et al.  A process for high yield and scaleable recovery of high purity eicosapentaenoic acid esters from microalgae and fish oil. , 2000, Enzyme and microbial technology.

[46]  G Antolín,et al.  Optimisation of biodiesel production by sunflower oil transesterification. , 2002, Bioresource technology.

[47]  A. Zarka,et al.  Nitrogen-fixing cyanobacteria as gene delivery system for expressing mosquitocidal toxins of Bacillus thuringiensis ssp. israelensis , 2000, Journal of Applied Phycology.

[48]  M. Komaitis,et al.  Lipid and γ-linolenic acid accumulation in strains of zygomycetes growing on glucose , 2001 .

[49]  E. Berry,et al.  Cold Temperature Adaptation and Growth of Microorganisms †. , 1997, Journal of food protection.

[50]  N Beales,et al.  Adaptation of Microorganisms to Cold Temperatures, Weak Acid Preservatives, Low pH, and Osmotic Stress: A Review. , 2004, Comprehensive reviews in food science and food safety.

[51]  G. Vicente,et al.  Integrated biodiesel production: a comparison of different homogeneous catalysts systems. , 2004, Bioresource technology.

[52]  G. Aggelis,et al.  Prediction of lipid accumulation-degradation in oleaginous micro-organisms growing on vegetable oils , 1997, Antonie van Leeuwenhoek.

[53]  T. Thomas,et al.  Strategies for modifying fatty acid composition in transgenic plants , 1998 .

[54]  P. Spolaore,et al.  Commercial applications of microalgae. , 2006, Journal of bioscience and bioengineering.

[55]  Rashmi,et al.  Prospects of biodiesel production from microalgae in India , 2009 .

[56]  A. Dalai,et al.  Preparation and characterization of bio-diesels from various bio-oils. , 2001, Bioresource technology.

[57]  M. Čertík,et al.  Biosynthesis and regulation of microbial polyunsaturated fatty acid production. , 1999, Journal of bioscience and bioengineering.

[58]  B. Metting,et al.  Biologically active compounds from microalgae , 1986 .

[59]  C. Ratledge,et al.  The biochemistry and molecular biology of lipid accumulation in oleaginous microorganisms. , 2002, Advances in applied microbiology.

[60]  G. Knothe Analyzing biodiesel: standards and other methods , 2006 .

[61]  Yusuf Chisti,et al.  Biotechnology-a sustainable alternative for chemical industry. , 2005, Biotechnology advances.

[62]  K. Vorlop,et al.  Development of an integrated bioconversion process for the production of 1,3-propanediol from raw glycerol waters , 2005 .

[63]  Z Zhang,et al.  Plasmid stability in recombinant Saccharomyces cerevisiae. , 1996, Biotechnology advances.

[64]  S. Papanikolaou,et al.  A mathematical model for the study of lipid accumulation in oleaginous microorganisms. I. Lipid accumulation during growth of Mucor circinelloides CBS 172-27 on a vegetable oil , 1995 .