The use of heparin chemistry to improve dental osteogenesis associated with implants.

[1]  Su A Park,et al.  Surface modification of 3D-printed porous scaffolds via mussel-inspired polydopamine and effective immobilization of rhBMP-2 to promote osteogenic differentiation for bone tissue engineering. , 2016, Acta biomaterialia.

[2]  Soong Ho Um,et al.  Titanium dental implants surface-immobilized with gold nanoparticles as osteoinductive agents for rapid osseointegration. , 2016, Journal of colloid and interface science.

[3]  E. Balmayor,et al.  Targeted delivery as key for the success of small osteoinductive molecules. , 2015, Advanced drug delivery reviews.

[4]  Su A. Park,et al.  Biofunctionalized titanium with anti-fouling resistance by grafting thermo-responsive polymer brushes for the prevention of peri-implantitis. , 2015, Journal of materials chemistry. B.

[5]  Sophia P Pilipchuk,et al.  Tissue engineering for bone regeneration and osseointegration in the oral cavity. , 2015, Dental materials : official publication of the Academy of Dental Materials.

[6]  Su A Park,et al.  Characterization and preparation of bio-tubular scaffolds for fabricating artificial vascular grafts by combining electrospinning and a 3D printing system. , 2015, Physical chemistry chemical physics : PCCP.

[7]  J. Chen,et al.  Covalent co-immobilization of heparin/laminin complex that with different concentration ratio on titanium surface for selectively direction of platelets and vascular cells behavior , 2014 .

[8]  L. Sennerby,et al.  One-year clinical and radiographic results with a novel hydrophilic titanium dental implant. , 2014, Clinical implant dentistry and related research.

[9]  Gorka Orive,et al.  Toward the biomimetic implant surface: Biopolymers on titanium-based implants for bone regeneration , 2014 .

[10]  Abraham Marmur,et al.  A review on the wettability of dental implant surfaces I: theoretical and experimental aspects. , 2014, Acta biomaterialia.

[11]  B. Boyan,et al.  A review on the wettability of dental implant surfaces II: Biological and clinical aspects. , 2014, Acta biomaterialia.

[12]  Jian Wang,et al.  Surface modification with dopamine and heparin/poly-L-lysine nanoparticles provides a favorable release behavior for the healing of vascular stent lesions. , 2014, ACS applied materials & interfaces.

[13]  Deok-Won Lee,et al.  Enhanced osteogenic differentiation of MC3T3-E1 on rhBMP-2-immobilized titanium via click reaction. , 2014, Carbohydrate polymers.

[14]  Yong-Dae Kwon,et al.  Photo-cured hyaluronic acid-based hydrogels containing growth and differentiation factor 5 (GDF-5) for bone tissue regeneration. , 2014, Bone.

[15]  Hae-Ryong Song,et al.  The effect of titanium with heparin/BMP-2 complex for improving osteoblast activity. , 2013, Carbohydrate polymers.

[16]  Li Jin,et al.  Growth differentiation factor 5 regulation in bone regeneration. , 2013, Current pharmaceutical design.

[17]  J. Park,et al.  Engineering biocompatible implant surfaces , 2013 .

[18]  Dietmar Werner Hutmacher,et al.  How smart do biomaterials need to be? A translational science and clinical point of view. , 2013, Advanced drug delivery reviews.

[19]  Min Soo Bae,et al.  ZrO₂ surface chemically coated with hyaluronic acid hydrogel loading GDF-5 for osteogenesis in dentistry. , 2013, Carbohydrate polymers.

[20]  Tien-Min G. Chu,et al.  Recent advances in the development of GTR/GBR membranes for periodontal regeneration--a materials perspective. , 2012, Dental materials : official publication of the Academy of Dental Materials.

[21]  Sung Eun Kim,et al.  Gentamicin and bone morphogenic protein-2 (BMP-2)-delivering heparinized-titanium implant with enhanced antibacterial activity and osteointegration. , 2012, Bone.

[22]  A. Khademhosseini,et al.  Osteoblastic/cementoblastic and neural differentiation of dental stem cells and their applications to tissue engineering and regenerative medicine. , 2012, Tissue engineering. Part B, Reviews.

[23]  Min Soo Bae,et al.  Effect of heparin and alendronate coating on titanium surfaces on inhibition of osteoclast and enhancement of osteoblast function. , 2011, Biochemical and biophysical research communications.

[24]  D. Cochran,et al.  Regeneration of Periodontal Tissues in Non-human Primates with rhGDF-5 and Beta-Tricalcium Phosphate , 2011, Journal of dental research.

[25]  M. Schenker,et al.  Angiogenesis in bone regeneration. , 2011, Injury.

[26]  G. Huynh-Ba,et al.  Early osseointegration to hydrophilic and hydrophobic implant surfaces in humans. , 2011, Clinical oral implants research.

[27]  D. Dickinson,et al.  Growth/differentiation factor-5: a candidate therapeutic agent for periodontal regeneration? A review of pre-clinical data. , 2010, Journal of clinical periodontology.

[28]  T. Albrektsson,et al.  Effects of titanium surface topography on bone integration: a systematic review. , 2009, Clinical oral implants research.

[29]  S. Ferguson,et al.  Potential of chemically modified hydrophilic surface characteristics to support tissue integration of titanium dental implants. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.

[30]  Y. Joung,et al.  Controlled release of heparin-binding growth factors using heparin-containing particulate systems for tissue regeneration , 2008 .

[31]  Carlos Nelson Elias,et al.  Relationship between surface properties (roughness, wettability and morphology) of titanium and dental implant removal torque. , 2008, Journal of the mechanical behavior of biomedical materials.

[32]  J. Kanczler,et al.  Osteogenesis and angiogenesis: the potential for engineering bone. , 2008, European cells & materials.

[33]  M. Wieland,et al.  The initial attachment and subsequent behavior regulation of osteoblasts by dental implant surface modification. , 2007, Journal of biomedical materials research. Part A.

[34]  M. MacDougall,et al.  Isolation and characterization of multipotent human periodontal ligament stem cells. , 2007, Orthodontics & craniofacial research.

[35]  P. Layrolle,et al.  Surface treatments of titanium dental implants for rapid osseointegration. , 2007, Dental materials : official publication of the Academy of Dental Materials.

[36]  G. Balian,et al.  Growth and differentiation factor-5 (GDF-5) stimulates osteogenic differentiation and increases vascular endothelial growth factor (VEGF) levels in fat-derived stromal cells in vitro. , 2007, Bone.

[37]  J. I. Qazi,et al.  Titanium alloys for biomedical applications , 2006 .

[38]  C. A. Dunn,et al.  BMP gene delivery for alveolar bone engineering at dental implant defects. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

[39]  P. Chu,et al.  Surface modification of titanium, titanium alloys, and related materials for biomedical applications , 2004 .

[40]  Stan Gronthos,et al.  Investigation of multipotent postnatal stem cells from human periodontal ligament , 2004, The Lancet.

[41]  D Buser,et al.  What is This? Downloaded from jdr.sagepub.com at PENNSYLVANIA STATE UNIV on February 23, 2013 For personal use only. No other uses without permission. International and American Associations for Dental ResearchRESEARCH REPORTS , 2004 .

[42]  R. Carano,et al.  Angiogenesis and bone repair. , 2003, Drug discovery today.

[43]  A. Reddi,et al.  The application of bone morphogenetic proteins to dental tissue engineering , 2003, Nature Biotechnology.

[44]  I. Ishikawa,et al.  Gene Expression of Growth Differentiation Factors in the Developing Periodontium of Rat Molars , 2003, Journal of dental research.

[45]  Mitsuo Niinomi,et al.  Recent research and development in titanium alloys for biomedical applications and healthcare goods , 2003 .

[46]  J. Feijen,et al.  Immobilization of heparin to EDC/NHS-crosslinked collagen. Characterization and in vitro evaluation. , 2001, Biomaterials.

[47]  J. Hubbell,et al.  Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[48]  M. Nugent.  Heparin sequencing brings structure to the function of complex oligosaccharides. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[49]  J. Hubbell,et al.  Development of fibrin derivatives for controlled release of heparin-binding growth factors. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[50]  M. McCracken,et al.  Dental implant materials: commercially pure titanium and titanium alloys. , 1999, Journal of prosthodontics : official journal of the American College of Prosthodontists.

[51]  J. Glowacki.  Angiogenesis in fracture repair. , 1998, Clinical orthopaedics and related research.

[52]  Mitsuo Niinomi,et al.  Mechanical properties of biomedical titanium alloys , 1998 .

[53]  I. Ishikawa,et al.  Gene expression of growth and differentiation factors-5, -6, and -7 in developing bovine tooth at the root forming stage. , 1998, Biochemical and biophysical research communications.

[54]  K. Miyazono,et al.  Growth/differentiation factor-5 induces angiogenesis in vivo. , 1997, Experimental cell research.

[55]  M. Pepper,et al.  Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity. , 1997, Cytokine & growth factor reviews.

[56]  T A Einhorn,et al.  Enhancement of fracture-healing. , 1995, The Journal of bone and joint surgery. American volume.

[57]  S. Soker,et al.  The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules. , 1992, The Journal of biological chemistry.

[58]  H. Moses,et al.  Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane , 1990, The Journal of cell biology.

[59]  R. Noort.  Titanium: The implant material of today , 1987 .

[60]  M. Sporn,et al.  Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[61]  Min Soo Bae,et al.  The effect of immobilization of heparin and bone morphogenic protein-2 (BMP-2) to titanium surfaces on inflammation and osteoblast function. , 2011, Biomaterials.

[62]  T. Inai,et al.  Growth Differentiation Factor 5 (GDF-5) Induces Matrix Metalloproteinase 2 (MMP-2) Expression in Periodontal Ligament Cells and Modulates MMP-2 and MMP-13 Activity in Osteoblasts: , 2010 .

[63]  H. Hansson,et al.  Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. , 1981, Acta orthopaedica Scandinavica.