Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.

[1]  Joseph Sodroski,et al.  Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[2]  Arun K. Ghosh,et al.  Altered HIV-1 Gag Protein Interactions with Cyclophilin A (CypA) on the Acquisition of H219Q and H219P Substitutions in the CypA Binding Loop* , 2006, Journal of Biological Chemistry.

[3]  D. Pérez-Caballero,et al.  Restriction of Human Immunodeficiency Virus Type 1 by TRIM-CypA Occurs with Rapid Kinetics and Independently of Cytoplasmic Bodies, Ubiquitin, and Proteasome Activity , 2005, Journal of Virology.

[4]  M. Soares,et al.  Evolution of Cyclophilin A and TRIMCyp Retrotransposition in New World Primates , 2005, Journal of Virology.

[5]  R. Ptak,et al.  Naturally Occurring Capsid Substitutions Render HIV-1 Cyclophilin A Independent in Human Cells and TRIM-cyclophilin-resistant in Owl Monkey Cells* , 2005, Journal of Biological Chemistry.

[6]  J. Sodroski,et al.  Retroviral Restriction Factor TRIM5α Is a Trimer , 2005, Journal of Virology.

[7]  S. Nisole,et al.  TRIM family proteins: retroviral restriction and antiviral defence , 2005, Nature Reviews Microbiology.

[8]  M. Bock,et al.  Capsid Processing Requirements for Abrogation of Fv1 and Ref1 Restriction , 2005, Journal of Virology.

[9]  J. Sodroski,et al.  The Contribution of RING and B-box 2 Domains to Retroviral Restriction Mediated by Monkey TRIM5α* , 2005, Journal of Biological Chemistry.

[10]  Y. Nagai,et al.  A Specific Region of 37 Amino Acid Residues in the SPRY (B30.2) Domain of African Green Monkey TRIM5α Determines Species-Specific Restriction of Simian Immunodeficiency Virus SIVmac Infection , 2005, Journal of Virology.

[11]  J. Luban,et al.  TRIM5α selectively binds a restriction-sensitive retroviral capsid , 2005, Retrovirology.

[12]  J. Sodroski,et al.  Retrovirus Restriction by TRIM5α Variants from Old World and New World Primates , 2005, Journal of Virology.

[13]  J. Sodroski,et al.  Species-Specific Variation in the B30.2(SPRY) Domain of TRIM5α Determines the Potency of Human Immunodeficiency Virus Restriction , 2005, Journal of Virology.

[14]  Michael Emerman,et al.  Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[15]  C. Aiken,et al.  Structural Requirements for Recognition of the Human Immunodeficiency Virus Type 1 Core during Host Restriction in Owl Monkey Cells , 2005, Journal of Virology.

[16]  Jonathan P. Stoye,et al.  A Single Amino Acid Change in the SPRY Domain of Human Trim5α Leads to HIV-1 Restriction , 2005, Current Biology.

[17]  D. Pérez-Caballero,et al.  Cyclophilin Interactions with Incoming Human Immunodeficiency Virus Type 1 Capsids with Opposing Effects on Infectivity in Human Cells , 2005, Journal of Virology.

[18]  A. Engelman,et al.  Class II Integrase Mutants with Changes in Putative Nuclear Localization Signals Are Primarily Blocked at a Postnuclear Entry Step of Human Immunodeficiency Virus Type 1 Replication , 2004, Journal of Virology.

[19]  J. Luban,et al.  Selection for Loss of Ref1 Activity in Human Cells Releases Human Immunodeficiency Virus Type 1 from Cyclophilin A Dependence during Infection , 2004, Journal of Virology.

[20]  S. Nisole,et al.  A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J. Sodroski,et al.  TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[22]  G. Towers,et al.  The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[23]  A. Yang,et al.  Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[24]  S. Nisole,et al.  Trim5α protein restricts both HIV-1 and murine leukemia virus , 2004 .

[25]  J. Luban,et al.  Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1 , 2004, Nature.

[26]  W. Sundquist,et al.  Species-Specific Tropism Determinants in the Human Immunodeficiency Virus Type 1 Capsid , 2004, Journal of Virology.

[27]  C. M. Owens,et al.  Binding and Susceptibility to Postentry Restriction Factors in Monkey Cells Are Specified by Distinct Regions of the Human Immunodeficiency Virus Type 1 Capsid , 2004, Journal of Virology.

[28]  D. A. Bosco,et al.  Catalysis and binding of cyclophilin A with different HIV-1 capsid constructs. , 2004, Biochemistry.

[29]  Wesley I. Sundquist,et al.  Assembly Properties of the Human Immunodeficiency Virus Type 1 CA Protein , 2004, Journal of Virology.

[30]  C. M. Owens,et al.  The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys , 2004, Nature.

[31]  P. Bieniasz,et al.  Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors , 2003, Nature Medicine.

[32]  P. Bieniasz,et al.  Restriction of multiple divergent retroviruses by Lv1 and Ref1 , 2003, The EMBO journal.

[33]  I. Verma,et al.  Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[34]  C. M. Owens,et al.  Human and Simian Immunodeficiency Virus Capsid Proteins Are Major Viral Determinants of Early, Postentry Replication Blocks in Simian Cells , 2003, Journal of Virology.

[35]  F. Diaz-Griffero,et al.  Endocytosis Is a Critical Step in Entry of Subgroup B Avian Leukosis Viruses , 2002, Journal of Virology.

[36]  G. Lucero,et al.  A dominant block to HIV-1 replication at reverse transcription in simian cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[37]  Y. Takeuchi,et al.  Restriction of lentivirus in monkeys , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[38]  P. Bieniasz,et al.  Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[39]  D. A. Bosco,et al.  Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Christopher J. Burrell,et al.  Kinetics of Human Immunodeficiency Virus Type 1 (HIV) DNA Integration in Acutely Infected Cells as Determined Using a Novel Assay for Detection of Integrated HIV DNA , 2001, Journal of Virology.

[41]  P. Boyer,et al.  Replication of Phenotypically Mixed Human Immunodeficiency Virus Type 1 Virions Containing Catalytically Active and Catalytically Inactive Reverse Transcriptase , 2001, Journal of Virology.

[42]  Frederic D. Bushman,et al.  A quantitative assay for HIV DNA integration in vivo , 2001, Nature Medicine.

[43]  Wesley I. Sundquist,et al.  Image reconstructions of helical assemblies of the HIV-1 CA protein , 2022 .

[44]  J. Sodroski,et al.  Species-Specific, Postentry Barriers to Primate Immunodeficiency Virus Infection , 1999, Journal of Virology.

[45]  C. Lawson,et al.  Model for lentivirus capsid core assembly based on crystal dimers of EIAV p26. , 1999, Journal of molecular biology.

[46]  J. Olsen.  Gene transfer vectors derived from equine infectious anemia virus , 1998, Gene Therapy.

[47]  W. Sundquist,et al.  Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV‐1 capsid protein , 1997, Protein science : a publication of the Protein Society.

[48]  C. Aiken.  Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A , 1997, Journal of virology.

[49]  W. Sundquist,et al.  Molecular recognition in the HIV-1 capsid/cyclophilin A complex. , 1997, Journal of molecular biology.

[50]  W. Sundquist,et al.  Crystal Structure of Human Cyclophilin A Bound to the Amino-Terminal Domain of HIV-1 Capsid , 1996, Cell.

[51]  Jeremy Luban,et al.  Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B , 1993, Cell.

[52]  A. Helenius,et al.  Pathway of vesicular stomatitis virus entry leading to infection. , 1982, Journal of molecular biology.

[53]  J. Luban,et al.  The retroviral restriction factor TRIM5alpha. , 2007, Current infectious disease reports.

[54]  J. Sodroski,et al.  Retrovirus restriction by TRIM5alpha variants from Old World and New World primates. , 2005, Journal of virology.

[55]  J. Sodroski,et al.  Retroviral restriction factor TRIM5alpha is a trimer. , 2005, Journal of virology.

[56]  S. Nisole,et al.  Trim5alpha protein restricts both HIV-1 and murine leukemia virus. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[57]  W. Sundquist,et al.  Assembly and analysis of conical models for the HIV-1 core. , 1999, Science.

[58]  P. Seglen.  Inhibitors of lysosomal function. , 1983, Methods in enzymology.