Lynch Syndrome Limbo: Patient Understanding of Variants of Uncertain Significance

[1]  Nikoletta Manioti.  EPIC SPACE , 2016, The Classical Review.

[2]  F. Couch,et al.  Genetic counselors' practices and confidence regarding variant of uncertain significance results and reclassification from BRCA testing , 2015, Clinical genetics.

[3]  J. Abraham,et al.  Understanding of BRCA VUS genetic results by breast cancer specialists , 2015, BMC Cancer.

[4]  E. Swisher,et al.  More genes, more problems? Benefits and risks of multiplex genetic testing. , 2015, Gynecologic oncology.

[5]  M. Frey,et al.  Rescreening for genetic mutations using multi-gene panel testing in patients who previously underwent non-informative genetic screening. , 2015, Gynecologic oncology.

[6]  T. Ross,et al.  Use of panel tests in place of single gene tests in the cancer genetics clinic , 2015, Clinical genetics.

[7]  F. Couch,et al.  A preliminary investigation of genetic counselors’ information needs when receiving a variant of uncertain significance result: a mixed methods study , 2015, Genetics in Medicine.

[8]  W. Chung,et al.  Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility , 2014, Genetics in Medicine.

[9]  M. West.  GREEK–MESOPOTAMIAN DIALOGUES , 2014, The Classical Review.

[10]  Randall W Burt,et al.  Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer. , 2014, Diseases of the colon and rectum.

[11]  Tina Pesaran,et al.  Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients , 2014, Genetics in Medicine.

[12]  Julie O. Culver,et al.  Variants of uncertain significance in BRCA testing: evaluation of surgical decisions, risk perception, and cancer distress , 2013, Clinical genetics.

[13]  P. Devilee,et al.  The impact of next generation sequencing on the analysis of breast cancer susceptibility: a role for extremely rare genetic variation? , 2013, Clinical Genetics.

[14]  Gail P Jarvik,et al.  Follow-up of carriers of BRCA1 and BRCA2 variants of unknown significance: Variant reclassification and surgical decisions , 2011, Genetics in Medicine.

[15]  Paul K. J. Han,et al.  Varieties of Uncertainty in Health Care , 2011 .

[16]  S. Crandall,et al.  Commentary: ambiguity and uncertainty: neglected elements of medical education curricula? , 2011, Academic medicine : journal of the Association of American Medical Colleges.

[17]  A. Stiggelbout,et al.  Family communication matters: The impact of telling relatives about unclassified variants and uninformative DNA-test results , 2011, Genetics in Medicine.

[18]  S. Weissman,et al.  Genetic Counseling Considerations in the Evaluation of Families for Lynch Syndrome—A Review , 2011, Journal of Genetic Counseling.

[19]  Paul K J Han,et al.  Varieties of uncertainty in health care: a conceptual taxonomy. , 2011, Medical decision making : an international journal of the Society for Medical Decision Making.

[20]  B. Ferrell,et al.  Women’s Perceptions of the Personal and Family Impact of Genetic Cancer Risk Assessment: Focus Group Findings , 2010, Journal of Genetic Counseling.

[21]  L. Huiart,et al.  Subjective interpretation of inconclusive BRCA1/2 cancer genetic test results and transmission of information to the relatives , 2009, Psycho-oncology.

[22]  W. Otten,et al.  The counsellees' view of an unclassified variant in BRCA1/2: recall, interpretation, and impact on life , 2008, Psycho-oncology.

[23]  J. Klijn,et al.  The common sense model of self‐regulation and psychological adjustment to predictive genetic testing: a prospective study , 2007, Psycho-oncology.

[24]  F. Wood,et al.  Knowledge and Expectations of Women Undergoing Cancer Genetic Risk Assessment: A Qualitative Analysis of Free-Text Questionnaire Comments , 2007, Journal of Genetic Counseling.

[25]  H. Valdimarsdottir,et al.  Tolerance for uncertainty and perceived risk among women receiving uninformative BRCA1/2 test results , 2006, American journal of medical genetics. Part C, Seminars in medical genetics.

[26]  W. Otten,et al.  Clinical characteristics affect the impact of an uninformative DNA test result: the course of worry and distress experienced by women who apply for genetic testing for breast cancer. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[27]  Harry Campbell,et al.  Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer. , 2006, The New England journal of medicine.

[28]  M. Henry,et al.  Uncertainty, responsibility, and the evolution of the physician/patient relationship , 2006, Journal of Medical Ethics.

[29]  W. Frankel,et al.  Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). , 2005, The New England journal of medicine.

[30]  M. Andreu,et al.  Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer. , 2005, JAMA.

[31]  W. Otten,et al.  Variants of uncertain clinical significance as a result of BRCA1/2 testing: impact of an ambiguous breast cancer risk message. , 2004, Genetic testing.

[32]  V. Venne,et al.  Decision Making with Uncertain Information: Learning from Women in a High Risk Breast Cancer Clinic , 2004, Journal of Genetic Counseling.

[33]  R. Eeles,et al.  Genetic testing for women previously diagnosed with breast/ovarian cancer: examining the impact of BRCA1 and BRCA2 mutation searching. , 2002, Genetic testing.

[34]  J. Kaprio,et al.  Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland. , 2000, The New England journal of medicine.

[35]  L. Aaltonen,et al.  Population-based molecular detection of hereditary nonpolyposis colorectal cancer. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[36]  A. Patenaude,et al.  Anticipated versus actual emotional reactions to disclosure of results of genetic tests for cancer susceptibility: findings from p53 and BRCA1 testing programs. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[37]  N. Hoffart.  Basics of Qualitative Research: Techniques and Procedures for Developing Grounded Theory , 2000 .

[38]  W. Levinson,et al.  Informed decision making in outpatient practice: time to get back to basics. , 1999, JAMA.

[39]  L. Aaltonen,et al.  Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. , 1998, The New England journal of medicine.

[40]  C. Boland,et al.  Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives. , 1995, Journal of the National Cancer Institute.

[41]  Yingzi Zhang,et al.  Uncertainty in Illness: Theory Review, Application, and Extension. , 2017, Oncology nursing forum.

[42]  A. Jemal,et al.  Cancer statistics, 2016 , 2016, CA: a cancer journal for clinicians.

[43]  A. Jemal,et al.  Cancer statistics, 2015 , 2015, CA: a cancer journal for clinicians.

[44]  E. Rimm,et al.  Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men , 2004, Cancer Causes & Control.

[45]  A. Babrow,et al.  The many meanings of uncertainty in illness: toward a systematic accounting. , 1998, Health communication.

[46]  Anselm L. Strauss,et al.  Basics of qualitative research : techniques and procedures for developing grounded theory , 1998 .

[47]  N. Dubrawsky.  Cancer statistics , 1989, CA: a cancer journal for clinicians.