Magnetic-resonance imaging of the human brain with an atomic magnetometer.

Magnetic resonance imaging (MRI) is conventionally performed in very high fields, and this leads to some restrictions in applications. To remove such restrictions, the ultra-low field MRI approach has been proposed. Because of the loss of sensitivity, the detection methods based on superconducting quantum interference devices (SQUIDs) in a shielded room were used. Atomic magnetometers have similar sensitivity as SQUIDs and can also be used for MRI, but there are some technical difficulties to overcome. We demonstrate that MRI of the human brain can be obtained with an atomic magnetometer with in-plane resolution of 3 mm in 13 min.

[1]  Dmitry Budker,et al.  Magnetic resonance imaging with an optical atomic magnetometer , 2006, Proceedings of the National Academy of Sciences.

[2]  Robert H Kraus,et al.  Microtesla MRI of the human brain combined with MEG. , 2008, Journal of magnetic resonance.

[3]  P L Volegov,et al.  MRI with an atomic magnetometer suitable for practical imaging applications. , 2009, Journal of magnetic resonance.

[4]  M. Romalis,et al.  NMR detection with an atomic magnetometer. , 2005, Physical review letters.

[5]  I Savukov,et al.  Anatomical MRI with an atomic magnetometer. , 2013, Journal of magnetic resonance.

[6]  I M Savukov,et al.  Detection of NMR signals with a radio-frequency atomic magnetometer. , 2007, Journal of magnetic resonance.

[7]  D Budker,et al.  Hyperpolarized xenon nuclear spins detected by optical atomic magnetometry. , 2004, Physical review letters.

[8]  T. Owens,et al.  SQUID-Based Microtesla MRI for In Vivo Relaxometry of the Human Brain , 2009, IEEE Transactions on Applied Superconductivity.