Rationally designed SERS active silica coated silver nanoparticles.

A reproducible method for the successful silica coating of silver nanoparticles is reported. A selection of tri-functional reporter molecules were designed to allow controlled synthesis of silica shelled, dye coded, SERS active silver nanoparticles.

[1]  Y. Ozaki,et al.  Surface-enhanced Raman scattering for protein detection , 2009, Analytical and bioanalytical chemistry.

[2]  Duncan Graham,et al.  Comparison of surface-enhanced resonance Raman scattering and fluorescence for detection of a labeled antibody. , 2008, Analytical chemistry.

[3]  Paul Mulvaney,et al.  Synthesis of Nanosized Gold−Silica Core−Shell Particles , 1996 .

[4]  Duncan Graham,et al.  SERRS dyes. Part I. Synthesis of benzotriazole monoazo dyes as model analytes for surface enhanced resonance Raman scattering. , 2002, The Analyst.

[5]  M. Hande,et al.  Cytotoxicity and genotoxicity of silver nanoparticles in human cells. , 2009, ACS nano.

[6]  Paul Mulvaney,et al.  Controlled Method for Silica Coating of Silver Colloids. Influence of Coating on the Rate of Chemical Reactions , 1998 .

[7]  Duncan Graham,et al.  SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence. , 2004, The Analyst.

[8]  S. Nie,et al.  In vivo cancer targeting and imaging with semiconductor quantum dots , 2004, Nature Biotechnology.

[9]  R. Niessner,et al.  Synthesis of core-shell surface-enhanced Raman tags for bioimaging. , 2010, Analytical chemistry.

[10]  Yoshio Kobayashi,et al.  Silica coating of silver nanoparticles using a modified Stober method. , 2005, Journal of colloid and interface science.

[11]  Duncan Graham,et al.  Quantitative SERRS for DNA sequence analysis. , 2008, Chemical Society reviews.

[12]  Alexander Marx,et al.  SERS labels for red laser excitation: silica-encapsulated SAMs on tunable gold/silver nanoshells. , 2009, Angewandte Chemie.

[13]  W. Stöber,et al.  Controlled growth of monodisperse silica spheres in the micron size range , 1968 .

[14]  C. Schmuck,et al.  Synthesis of glass-coated SERS nanoparticle probes via SAMs with terminal SiO2 precursors. , 2010, Small.

[15]  K. Lieser,et al.  Darstellung stabiler Hydrosole von Gold und Silber durch Reduktion mit Äthylendiamintetraessigsäure , 1963 .

[16]  J. C. Jones,et al.  Synthesis of novel monoazo benzotriazole dyes specifically for surface enhanced resonance Raman scattering , 1998 .

[17]  Duncan Graham,et al.  Quantitative enhanced Raman scattering of labeled DNA from gold and silver nanoparticles. , 2007, Small.

[18]  M. Quinten.  Local fields and Poynting vectors in the vicinity of the surface of small spherical particles , 1995 .

[19]  M. Natan,et al.  Glass-Coated, Analyte-Tagged Nanoparticles: A New Tagging System Based on Detection with Surface-Enhanced Raman Scattering , 2003 .

[20]  Janina Kneipp,et al.  In vivo molecular probing of cellular compartments with gold nanoparticles and nanoaggregates. , 2006, Nano letters.