Summary: epigenetics--from phenomenon to field.

[1]  H. Weintraub The assembly of newly replicated DNA into chromatin. , 1974, Cold Spring Harbor symposia on quantitative biology.

[2]  K. Nasmyth,et al.  Physical analysis of mating-type loci in Saccharomyces cerevisiae. , 1981, Cold Spring Harbor symposia on quantitative biology.

[3]  T. Mohandas,et al.  DNA methylation and the control of gene expression on the human X chromosome. , 1983, Cold Spring Harbor symposia on quantitative biology.

[4]  A. Campbell Some general questions about movable elements and their implications. , 1981, Cold Spring Harbor symposia on quantitative biology.

[5]  P. Chambon Summary: the molecular biology of the eukaryotic genome is coming of age. , 1978, Cold Spring Harbor symposia on quantitative biology.

[6]  H. Willard,et al.  Epigenetic and chromosomal control of gene expression: molecular and genetic analysis of X chromosome inactivation. , 1993, Cold Spring Harbor symposia on quantitative biology.

[7]  David A Low,et al.  The mechanism by which DNA adenine methylase and PapI activate the pap epigenetic switch. , 2003, Molecular cell.

[8]  A. Razin,et al.  Effect of DNA methylation on gene expression. , 1983, Cold Spring Harbor symposia on quantitative biology.

[9]  M. Osley H2B ubiquitylation: the end is in sight. , 2004, Biochimica et biophysica acta.

[10]  J. Locke,et al.  Dosage-dependent modifiers of position effect variegation in Drosophila and a mass action model that explains their effect. , 1988, Genetics.

[11]  R. Sternglanz,et al.  Esc1, a Nuclear Periphery Protein Required for Sir4-Based Plasmid Anchoring and Partitioning , 2002, Molecular and Cellular Biology.

[12]  S. Bell,et al.  The replicon model and eukaryotic chromosomes. , 1993, Cold Spring Harbor symposia on quantitative biology.

[13]  J. Schultz The relation of the heterochromatic chromosome regions to the nucleic acids of the cell. , 1956, Cold Spring Harbor symposia on quantitative biology.

[14]  B. S. Baker,et al.  Control of sexual differentiation in Drosophila melanogaster. , 1985, Cold Spring Harbor symposia on quantitative biology.

[15]  R. Jaenisch,et al.  DNA methylation, genomic imprinting, and mammalian development. , 1993, Cold Spring Harbor symposia on quantitative biology.

[16]  Michael Grunstein,et al.  Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast , 1994, Nature.

[17]  Steven J Altschuler,et al.  Genomic characterization reveals a simple histone H4 acetylation code. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[18]  M. Reitman,et al.  Chromatin structure of transcriptionally active genes. , 1993, Cold Spring Harbor symposia on quantitative biology.

[19]  I. Herskowitz,et al.  Pattern of switching and fate of the replaced cassette in yeast mating-type interconversion. , 1981, Cold Spring Harbor symposia on quantitative biology.

[20]  M. Gartenberg,et al.  Yeast heterochromatin is a dynamic structure that requires silencers continuously. , 2000, Genes & development.

[21]  Jasper Rine,et al.  Epigenetic inheritance of transcriptional states in S. cerevisiae , 1989, Cell.

[22]  J. Rine,et al.  A transcriptional silencer as a specialized origin of replication that establishes functional domains of chromatin. , 1993, Cold Spring Harbor symposia on quantitative biology.

[23]  Renato Paro,et al.  Distinct contributions of histone H3 lysine 9 and 27 methylation to locus-specific stability of polycomb complexes. , 2004, Molecular cell.

[24]  W. Doerfler,et al.  DNA methylation and gene activity: the adenovirus system as a model. , 1983, Cold Spring Harbor symposia on quantitative biology.

[25]  J. Broach,et al.  Sites required for position-effect regulation of mating-type information in yeast. , 1983, Cold Spring Harbor symposia on quantitative biology.

[26]  Edward J. Louis,et al.  Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres , 1998, Current Biology.

[27]  R. Sternglanz,et al.  Perinuclear localization of chromatin facilitates transcriptional silencing , 1998, Nature.

[28]  H. Cedar,et al.  Demethylation and the establishment of kappa allelic exclusion. , 1999, Cold Spring Harbor Symposia on Quantitative Biology.

[29]  E. Gilson,et al.  The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane. , 1993, Cold Spring Harbor symposia on quantitative biology.

[30]  Philip R. Gafken,et al.  Heritable chromatin structure: Mapping “memory” in histones H3 and H4 , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[31]  G. Felsenfeld,et al.  The establishment of active chromatin domains. , 1998, Cold Spring Harbor symposia on quantitative biology.

[32]  D. Brutlag,et al.  The organization of highly repeated DNA sequences in Drosophila melanogaster chromosomes. , 1974, Cold Spring Harbor symposia on quantitative biology.

[33]  B. Mcclintock,et al.  Controlling elements and the gene. , 1956, Cold Spring Harbor symposia on quantitative biology.

[34]  G. Veenstra,et al.  Histone deacetylase directs the dominant silencing of transcription in chromatin: association with MeCP2 and the Mi-2 chromodomain SWI/SNF ATPase. , 1998, Cold Spring Harbor symposia on quantitative biology.

[35]  Brink Ra Paramutation at the R locus in maize. , 1958 .

[36]  Benjamin Tycko,et al.  Creation of genomic methylation patterns , 1996, Nature Genetics.

[37]  J. Hayes,et al.  Structures and interactions of the core histone tail domains. , 2003, Biopolymers.

[38]  S. J. Flint,et al.  The generation and propagation of variegated chromosome structures. , 1978, Cold Spring Harbor symposia on quantitative biology.

[39]  J. Jorcano,et al.  In vitro core particle and nucleosome assembly at physiological ionic strength. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[40]  E. Candido,et al.  Enzymatic modifications and their possible roles in regulating the binding of basic proteins to DNA and in controlling chromosomal structure. , 1974, Cold Spring Harbor symposia on quantitative biology.

[41]  T. Richmond,et al.  Crystal structure of the nucleosome core particle at 2.8 Å resolution , 1997, Nature.

[42]  H. Swift The organization of genetic material in eukaryotes: progress and prospects. , 1974, Cold Spring Harbor symposia on quantitative biology.

[43]  S. Gartler,et al.  SELECTION IN MAMMALIAN MOSAIC CELL POPULATIONS. , 1964, Cold Spring Harbor symposia on quantitative biology.

[44]  W. Wood,et al.  Aspects of dosage compensation and sex determination in Caenorhabditis elegans. , 1985, Cold Spring Harbor symposia on quantitative biology.

[45]  Michael A. Freitas,et al.  Identification of novel histone post-translational modifications by peptide mass fingerprinting , 2003, Chromosoma.

[46]  P. Garrett-engele,et al.  Dissection of the signal for DNA methylation in the zeta-eta region of Neurospora. , 1993, Cold Spring Harbor symposia on quantitative biology.

[47]  B. Mcclintock,et al.  Chromosome organization and genic expression. , 1951, Cold Spring Harbor symposia on quantitative biology.

[48]  W. Nance GENETIC TESTS WITH A SEX-LINKED MARKER: GLUCOSE-6-PHOSPHATE DEHYDROGENASE. , 1964, Cold Spring Harbor symposia on quantitative biology.

[49]  Phillip D Zamore,et al.  Perspective: machines for RNAi. , 2005, Genes & development.

[50]  T. Cline,et al.  Sex-lethal, a link between sex determination and sexual differentiation in Drosophila melanogaster. , 1985, Cold Spring Harbor symposia on quantitative biology.

[51]  K. Glaser,et al.  Histone deacetylase inhibitors: the Abbott experience. , 2003, Current medicinal chemistry.

[52]  E. Lewis Regulation of the genes of the bithorax complex in Drosophila. , 1985, Cold Spring Harbor symposia on quantitative biology.

[53]  G. T. Rudkin,et al.  Repetitive DNA in polytene chromosomes of Drosophila melanogaster. , 1974, Cold Spring Harbor symposia on quantitative biology.

[54]  Stefan Kubicek,et al.  A Crack in Histone Lysine Methylation , 2004, Cell.

[55]  R. Goldschmidt Chromosomes and genes. , 1951, Cold Spring Harbor symposia on quantitative biology.

[56]  A. Udvardy,et al.  Genetic and molecular analysis of chromatin domains. , 1993, Cold Spring Harbor symposia on quantitative biology.

[57]  A. Klar,et al.  The mechanism of fission yeast mating-type interconversion: evidence for two types of epigenetically inherited chromosomal imprinted events. , 1993, Cold Spring Harbor symposia on quantitative biology.

[58]  A. Webber,et al.  Parental imprinting of the H19 and Igf2 genes in the mouse. , 1993, Cold Spring Harbor symposia on quantitative biology.

[59]  U. K. Laemmli,et al.  Relation of chromosome structure and gene expression. , 1987, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[60]  O. Aparicio,et al.  Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way. , 1994, Genes & development.

[61]  J. Hodgkin,et al.  The sex determination pathway in the nematode Caenorhabditis elegans: variations on a theme. , 1985, Cold Spring Harbor symposia on quantitative biology.

[62]  V. Jackson Deposition of newly synthesized histones: hybrid nucleosomes are not tandemly arranged on daughter DNA strands. , 1988, Biochemistry.

[63]  S. Mai Sir2 : An NAD-dependent histone deacetylase that connects chromatin silencing metabolism, and aging. Cold Spring Harbor Symp , 2000 .

[64]  B. Morgan,et al.  Histone H4 and the maintenance of genome integrity. , 1995, Genes & development.

[65]  E. Beutler GENE INACTIVATION: THE DISTRIBUTION OF GENE PRODUCTS AMONG POPULATIONS OF CELLS IN HETEROZYGOUS HUMANS. , 1964, Cold Spring Harbor symposia on quantitative biology.

[66]  M. Lyon Gene Action in the X-chromosome of the Mouse (Mus musculus L.) , 1961, Nature.

[67]  C. Pannetier,et al.  Bias in the expression of IL-4 alleles: the use of T cells from a GFP knock-in mouse. , 1999, Cold Spring Harbor symposia on quantitative biology.

[68]  C. Allis,et al.  Translating the Histone Code , 2001, Science.

[69]  M. Grunstein,et al.  Histones and the regulation of heterochromatin in yeast. , 1993, Cold Spring Harbor symposia on quantitative biology.

[70]  J. Frankel Positional order and cellular handedness. , 1990, Journal of cell science.

[71]  S. Gilbert,et al.  Nuclear transfer in mouse embryos: activation of the embryonic genome. , 1985, Cold Spring Harbor Symposia on Quantitative Biology.

[72]  H. Muller INDUCED MUTATIONS IN DROSOPHILA , 1941 .

[73]  B. Cattanach,et al.  Differential activity of maternally and paternally derived chromosome regions in mice , 1985, Nature.

[74]  Sanjay K. Chhablani,et al.  Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. , 1993, Genes & development.

[75]  A. Bird,et al.  Coupled demethylation of sites in a conserved sequence of Xenopus ribosomal DNA. , 1983, Cold Spring Harbor symposia on quantitative biology.

[76]  A. Bird,et al.  Functions for DNA methylation in vertebrates. , 1993, Cold Spring Harbor symposia on quantitative biology.

[77]  M. Grunstein,et al.  Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[78]  M. McVey,et al.  Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging. , 2000, Cold Spring Harbor symposia on quantitative biology.

[79]  A. Feinberg,et al.  Loss of imprinting in human cancer. , 1994, Cold Spring Harbor symposia on quantitative biology.

[80]  M. Gotta,et al.  Targeting Sir proteins to sites of action: a general mechanism for regulated repression. , 1998, Cold Spring Harbor symposia on quantitative biology.

[81]  J. Rine,et al.  Silencers, silencing, and heritable transcriptional states. , 1992, Microbiological reviews.

[82]  P. Borst,et al.  Control of Antigenic Variation in African Trypanosomas , 1993 .

[83]  T. Grigliatti,et al.  The effect of modifiers of position-effect variegation on the variegation of heterochromatic genes of Drosophila melanogaster. , 1991, Genetics.

[84]  D. L. Nanney,et al.  Epigenetic factors affecting mating type expression in certain ciliates. , 1958, Cold Spring Harbor symposia on quantitative biology.

[85]  J. Karn,et al.  Phosphorylation of DNA-binding nuclear acidic proteins and gene activation in the HeLa cell cycle. , 1974, Cold Spring Harbor Symposia on Quantitative Biology.

[86]  S. Henikoff,et al.  Characterization of sequences responsible for trans-inactivation of the Drosophila brown gene. , 1993, Cold Spring Harbor symposia on quantitative biology.

[87]  Charles Kooperberg,et al.  The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. , 2004, Genes & development.

[88]  Tom Misteli,et al.  Maintenance of Stable Heterochromatin Domains by Dynamic HP1 Binding , 2003, Science.