Therapeutic targets for HIV-1 infection in the host proteome

[1]  F. Kashanchi,et al.  Antiviral Activity of CYC202 in HIV-1-infected Cells* , 2005, Journal of Biological Chemistry.

[2]  S. Zeichner,et al.  Host Cell Gene Expression during Human Immunodeficiency Virus Type 1 Latency and Reactivation and Effects of Targeting Genes That Are Differentially Expressed in Viral Latency , 2004, Journal of Virology.

[3]  K. Jeang,et al.  Specific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complex , 2004, Retrovirology.

[4]  F. Kashanchi,et al.  The expanding role of Tax in transcription , 2004, Retrovirology.

[5]  B. Berkhout,et al.  Inhibiting HIV-1 entry with fusion inhibitors. , 2003, Current medicinal chemistry.

[6]  M. Stevenson,et al.  HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection , 2003, Nature.

[7]  Jaakko Astola,et al.  Analysis and Visualization of Gene Expression Microarray Data in Human Cancer Using Self-Organizing Maps , 2003, Machine Learning.

[8]  Hiroaki Sakurai,et al.  ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, shows antimetastatic activity using a hepatocellular carcinoma model. , 2003, Molecular cancer therapeutics.

[9]  F. Kashanchi,et al.  Pharmacological cyclin-dependent kinase inhibitors as HIV-1 antiviral therapeutics. , 2003, Current HIV research.

[10]  F. Kashanchi,et al.  Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 tax expressing cells , 2003, Molecular and Cellular Biochemistry.

[11]  M. Hart,et al.  Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin. , 2003, The Journal of general virology.

[12]  Jerome H. Kim,et al.  HIV-1 Vpr activates cell cycle inhibitor p21/Waf1/Cip1: a potential mechanism of G2/M cell cycle arrest. , 2003, Virology.

[13]  Roger E Bumgarner,et al.  Cellular Gene Expression upon Human Immunodeficiency Virus Type 1 Infection of CD4+-T-Cell Lines , 2003, Journal of Virology.

[14]  A. Giordano,et al.  Cdk9, a member of the cdc2-like family of kinases, binds to gp130, the receptor of the IL-6 family of cytokines , 2002, Oncogene.

[15]  C. Ambrosino,et al.  Physical and Functional Interaction of HIV-1 Tat with E2F-4, a Transcriptional Regulator of Mammalian Cell Cycle* , 2002, The Journal of Biological Chemistry.

[16]  L. Meijer,et al.  Pharmacological Cyclin-Dependent Kinase Inhibitors Inhibit Replication of Wild-Type and Drug-Resistant Strains of Herpes Simplex Virus and Human Immunodeficiency Virus Type 1 by Targeting Cellular, Not Viral, Proteins , 2002, Journal of Virology.

[17]  F. Kashanchi,et al.  Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals , 2002, BMC Biochemistry.

[18]  T. Shirasawa,et al.  Transgenic expression of the EXT2 gene in developing chondrocytes enhances the synthesis of heparan sulfate and bone formation in mice. , 2002, Biochemical and biophysical research communications.

[19]  T. Maniatis,et al.  An extensive network of coupling among gene expression machines , 2002, Nature.

[20]  J. Dausset,et al.  Monocytes and T lymphocytes in HIV-1-positive patients express HLA-G molecule , 2002, AIDS.

[21]  F. Kashanchi,et al.  Enhancement of Nuclear Factor-κB Acetylation by Coactivator p300 and HIV-1 Tat Proteins* , 2002, The Journal of Biological Chemistry.

[22]  M. Tremblay,et al.  Presence of Host ICAM-1 in Laboratory and Clinical Strains of Human Immunodeficiency Virus Type 1 Increases Virus Infectivity and CD4+-T-Cell Depletion in Human Lymphoid Tissue, a Major Site of Replication In Vivo , 2002, Journal of Virology.

[23]  J. Schlom,et al.  Enhanced activation of rhesus T cells by vectors encoding a triad of costimulatory molecules (B7-1, ICAM-1, LFA-3). , 2001, Vaccine.

[24]  Graça Raposo,et al.  HIV-1 Nef impairs MHC class II antigen presentation and surface expression , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[25]  M. Lederman,et al.  HIV-1 infection impairs cell cycle progression of CD4(+) T cells without affecting early activation responses. , 2001, The Journal of clinical investigation.

[26]  L. Meijer,et al.  Inhibition of Human Immunodeficiency Virus Type 1 Transcription by Chemical Cyclin-Dependent Kinase Inhibitors , 2001, Journal of Virology.

[27]  B. Clarke,et al.  Cell cycle aberrations in the pathogenesis of squamous cell carcinoma of the uterine cervix. , 2001, Gynecologic oncology.

[28]  L Leoni,et al.  Temporal gene regulation during HIV-1 infection of human CD4+ T cells. , 2001, Genome research.

[29]  M. Tremblay,et al.  Neuraminidase from a bacterial source enhances both HIV-1-mediated syncytium formation and the virus binding/entry process. , 2001, Virology.

[30]  S. Brogna,et al.  Dribble, the Drosophila KRR1p homologue, is involved in rRNA processing. , 2001, Molecular biology of the cell.

[31]  K. Sandhoff,et al.  Degradation of membrane-bound ganglioside GM2 by beta -hexosaminidase A. Stimulation by GM2 activator protein and lysosomal lipids. , 2001, The Journal of biological chemistry.

[32]  M. Moriuchi,et al.  Octamer Transcription Factors Up-regulate the Expression of CCR5, a Coreceptor for HIV-1 Entry* , 2001, The Journal of Biological Chemistry.

[33]  Y. Kikuchi,et al.  Yeast Krr1p Physically and Functionally Interacts with a Novel Essential Kri1p, and Both Proteins Are Required for 40S Ribosome Biogenesis in the Nucleolus , 2000, Molecular and Cellular Biology.

[34]  F. Kashanchi,et al.  Loss of G1/S Checkpoint in Human Immunodeficiency Virus Type 1-Infected Cells Is Associated with a Lack of Cyclin-Dependent Kinase Inhibitor p21/Waf1 , 2000, Journal of Virology.

[35]  F. Kashanchi,et al.  Cell Cycle-Regulated Transcription by the Human Immunodeficiency Virus Type 1 Tat Transactivator , 2000, Journal of Virology.

[36]  M. Mizokami,et al.  Human IgM Monoclonal Antibody to Ganglioside GM2 and Complement Suppress Virus Propagation in Ex Vivo Cultures of Lymphocytes from HIV‐1 Infected Patients , 1999, Microbiology and immunology.

[37]  D. Baltimore,et al.  The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. , 1999, Immunity.

[38]  C. Thiele,et al.  Inflammatory cytokines and HIV-1-associated neurodegeneration: oncostatin-M produced by mononuclear cells from HIV-1-infected individuals induces apoptosis of primary neurons. , 1999, Journal of immunology.

[39]  A. Chalian,et al.  Intracellular adhesion molecule-1 modulates beta-chemokines and directly costimulates T cells in vivo. , 1999, The Journal of clinical investigation.

[40]  H. Koeffler,et al.  Functions of Cyclin A1 in the Cell Cycle and Its Interactions with Transcription Factor E2F-1 and the Rb Family of Proteins , 1999, Molecular and Cellular Biology.

[41]  R. Irie,et al.  Complement-mediated anti-HIV-1 effect induced by human IgM monoclonal antibody against ganglioside GM2. , 1999, Journal of immunology.

[42]  A. Giordano,et al.  HIV-1 Tat Elongates the G1 Phase and Indirectly Promotes HIV-1 Gene Expression in Cells of Glial Origin* , 1998, The Journal of Biological Chemistry.

[43]  Y. Ito,et al.  Human immunodeficiency virus type-1 envelope glycoprotein gp120 induces expression of fusion regulatory protein (FRP)-1/CD98 on CD4+ T cells: a possible regulatory mechanism of HIV-induced syncytium formation. , 1997 .

[44]  D. Latchman,et al.  The octamer-binding proteins Oct-1 and Oct-2 repress the HIV long terminal repeat promoter and its transactivation by Tat. , 1997, The Biochemical journal.

[45]  H. Haugen,et al.  Regulation of an extrathymic T-cell development pathway by oncostatin M , 1996, Nature.

[46]  D. Latchman,et al.  Functional interaction between the HIV-1 Tat transactivator and the inhibitory domain of the Oct-2 cellular transcription factor , 1996, AIDS.

[47]  M. Dierich,et al.  Efficient destruction of human immunodeficiency virus in human serum by inhibiting the protective action of complement factor H and decay accelerating factor (DAF, CD55) , 1996, The Journal of experimental medicine.

[48]  G. Peters,et al.  Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins. , 1995, Oncogene.

[49]  K. Pollok,et al.  Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP , 1995, The Journal of experimental medicine.

[50]  G. Sutherland,et al.  Moslecular and biological characterization of human 4‐1BB and its ligands , 1994, European journal of immunology.

[51]  P. Gallay,et al.  Syndecan captures, protects, and transmits HIV to T lymphocytes. , 2003, Immunity.

[52]  F. Kashanchi,et al.  Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins. , 2002, The Journal of biological chemistry.

[53]  R. Gromadka,et al.  The KRR1 gene encodes a protein required for 18S rRNA synthesis and 40S ribosomal subunit assembly in Saccharomyces cerevisiae. , 2000, Acta biochimica Polonica.

[54]  Esa Alhoniemi,et al.  SOM Toolbox for Matlab 5 , 2000 .

[55]  Teuvo Kohonen,et al.  Self-Organizing Maps , 2010 .

[56]  G. Shanmugam,et al.  Retinoblastoma gene inhibits transactivation of HIV-LTR linked gene expression upon co-transfection in He La cells. , 1993, Biochemistry and molecular biology international.