Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators

[1]  Hao Yan,et al.  Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators , 2020, Cell.

[2]  Duo Ma,et al.  A Multiplexed, Electrochemical Interface for Gene Circuit-Based Sensors , 2019, Nature Chemistry.

[3]  Peng Yin,et al.  De-Novo-Designed Translation-Repressing Riboregulators for Multi-Input Cellular Logic , 2019, Nature chemical biology.

[4]  Niles A. Pierce,et al.  Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacterial and Mammalian Cells via Dynamic RNA Nanotechnology , 2019, ACS central science.

[5]  Friedrich C Simmel,et al.  Switching the activity of Cas12a using guide RNA strand displacement circuits , 2019, Nature Communications.

[6]  F. Ceccherini‐Silberstein,et al.  HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon , 2019, BMC Infectious Diseases.

[7]  D. Melzer,et al.  Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank , 2019, British Medical Journal.

[8]  Ka-Hei Siu,et al.  Riboregulated toehold-gated gRNA for programmable CRISPR–Cas9 function , 2018, Nature Chemical Biology.

[9]  Jennifer A. Doudna,et al.  Programmed DNA destruction by miniature CRISPR-Cas14 enzymes , 2018, Science.

[10]  Duo Ma,et al.  Low-cost detection of norovirus using paper-based cell-free systems and synbody-based viral enrichment , 2018, Synthetic biology.

[11]  Sebastian J Maerkl,et al.  A simple, robust, and low-cost method to produce the PURE cell - free system , 2018, bioRxiv.

[12]  R. Parker,et al.  A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells , 2018, Nature Chemical Biology.

[13]  Hayden C. Metsky,et al.  Field-deployable viral diagnostics using CRISPR-Cas13 , 2018, Science.

[14]  Jennifer A. Doudna,et al.  CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity , 2018, Science.

[15]  James J. Collins,et al.  Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6 , 2018, Science.

[16]  R. Richards-Kortum,et al.  Paper-based detection of HIV-1 drug resistance using isothermal amplification and an oligonucleotide ligation assay , 2018, Analytical biochemistry.

[17]  Shun Liu,et al.  RMBase v2.0: deciphering the map of RNA modifications from epitranscriptome sequencing data , 2017, Nucleic Acids Res..

[18]  Tingrui Pan,et al.  Synthetic microbial consortia enable rapid assembly of pure translation machinery. , 2018, Nature chemical biology.

[19]  Rohan T Ranasinghe,et al.  Detecting RNA base methylations in single cells by in situ hybridization , 2018, Nature Communications.

[20]  Zhiheng Xu,et al.  American Strain of Zika Virus Causes More Severe Microcephaly Than an Old Asian Strain in Neonatal Mice , 2017, EBioMedicine.

[21]  L. Roberts.  Drug-resistant malaria advances in Mekong. , 2017, Science.

[22]  Nicholas J White,et al.  Spread of a single multidrug resistant malaria parasite lineage (PfPailin) to Vietnam. , 2017, The Lancet. Infectious diseases.

[23]  Tao Pan,et al.  Dynamic RNA Modifications in Gene Expression Regulation , 2017, Cell.

[24]  J. Collins,et al.  Complex cellular logic computation using ribocomputing devices , 2017, Nature.

[25]  Gideon Rechavi,et al.  Nm-seq maps 2′-O-methylation sites in human mRNA with base precision , 2017, Nature Methods.

[26]  Aviv Regev,et al.  Nucleic acid detection with CRISPR-Cas13a/C2c2 , 2017, Science.

[27]  A. Green.  Construction and In Vivo Testing of Prokaryotic Riboregulators. , 2017, Methods in molecular biology.

[28]  Eric S. Lander,et al.  C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector , 2016, Science.

[29]  Guillaume Lambert,et al.  Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components , 2016, Cell.

[30]  Amadou A. Sall,et al.  The Brazilian Zika virus strain causes birth defects in experimental models , 2016, Nature.

[31]  Georg Seelig,et al.  An Engineered Kinetic Amplification Mechanism for Single Nucleotide Variant Discrimination by DNA Hybridization Probes. , 2016, Journal of the American Chemical Society.

[32]  Ingrid A. Beck,et al.  Simplified Paper Format for Detecting HIV Drug Resistance in Clinical Specimens by Oligonucleotide Ligation , 2016, PloS one.

[33]  Adam J. Riesselman,et al.  3D RNA and Functional Interactions from Evolutionary Couplings , 2015, Cell.

[34]  D. Zhang,et al.  Simulation-Guided DNA Probe Design for Consistently Ultraspecific Hybridization , 2015, Nature chemistry.

[35]  Mads Thomassen,et al.  Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. , 2015, JAMA.

[36]  James Chappell,et al.  Creating small transcription activating RNAs. , 2015, Nature chemical biology.

[37]  Howard Y. Chang,et al.  Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification. , 2015, Journal of the American Chemical Society.

[38]  Myrielle Dupont-Rouzeyrol,et al.  Detection of Zika Virus in Urine , 2015, Emerging infectious diseases.

[39]  J. Collins,et al.  Toehold Switches: De-Novo-Designed Regulators of Gene Expression , 2014, Cell.

[40]  James J. Collins,et al.  Paper-Based Synthetic Gene Networks , 2014, Cell.

[41]  Grigory S. Filonov,et al.  Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution , 2014, Journal of the American Chemical Society.

[42]  Flavio Romano,et al.  A nucleotide-level coarse-grained model of RNA. , 2014, The Journal of chemical physics.

[43]  Georg Seelig,et al.  Conditionally fluorescent molecular probes for detecting single base changes in double-stranded DNA. , 2013, Nature chemistry.

[44]  Thomas E. Landrain,et al.  De novo automated design of small RNA circuits for engineering synthetic riboregulation in living cells , 2012, Proceedings of the National Academy of Sciences.

[45]  Adam P Arkin,et al.  Supplementary information for Rationally designed families of orthogonal RNA regulators of translation , 2012 .

[46]  Peng Yin,et al.  Optimizing the specificity of nucleic acid hybridization. , 2012, Nature chemistry.

[47]  S. Jaffrey,et al.  RNA Mimics of Green Fluorescent Protein , 2011, Science.

[48]  Adam P Arkin,et al.  Versatile RNA-sensing transcriptional regulators for engineering genetic networks , 2011, Proceedings of the National Academy of Sciences.

[49]  Conrad Steenberg,et al.  NUPACK: Analysis and design of nucleic acid systems , 2011, J. Comput. Chem..

[50]  D. Baker,et al.  Atomic accuracy in predicting and designing non-canonical RNA structure , 2010, Nature Methods.

[51]  G. Church,et al.  Synthetic Gene Networks That Count , 2009, Science.

[52]  M. Wainberg,et al.  Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance , 2009, Retrovirology.

[53]  Amber R. Davis,et al.  Thermodynamic characterization of single mismatches found in naturally occurring RNA. , 2007, Biochemistry.

[54]  Olaf Piepenburg,et al.  DNA Detection Using Recombination Proteins , 2006, PLoS biology.

[55]  D. Easton,et al.  Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies , 2005, Journal of Medical Genetics.

[56]  Farren J. Isaacs,et al.  Engineered riboregulators enable post-transcriptional control of gene expression , 2004, Nature Biotechnology.

[57]  V. Erdmann,et al.  Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA. , 2003, Nucleic acids research.

[58]  A. Syvänen.  Accessing genetic variation: genotyping single nucleotide polymorphisms , 2001, Nature Reviews Genetics.

[59]  Takuya Ueda,et al.  Cell-free translation reconstituted with purified components , 2001, Nature Biotechnology.

[60]  G. Varani,et al.  The G x U wobble base pair. A fundamental building block of RNA structure crucial to RNA function in diverse biological systems. , 2000, EMBO reports.

[61]  C. Katlama,et al.  HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy , 2000, AIDS.

[62]  J. Sabina,et al.  Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. , 1999, Journal of molecular biology.

[63]  Michael Zuker,et al.  Algorithms and Thermodynamics for RNA Secondary Structure Prediction: A Practical Guide , 1999 .

[64]  L. Poulsen,et al.  New Unstable Variants of Green Fluorescent Protein for Studies of Transient Gene Expression in Bacteria , 1998, Applied and Environmental Microbiology.

[65]  D. Turner,et al.  Predicting thermodynamic properties of RNA. , 1995, Methods in enzymology.

[66]  Rascon.  [The National Cancer Institute]. , 1953, Boletin cultural e informativo - Consejo General de Colegios Medicos de Espana.