Optical Cell Manipulation

In current biotechnology and biomedicine, cell-based investigations are rapidly gaining importance due to the recognition that molecular research alone does not provide a sufficiently complex insight. The high cost of animal studies and the fact that their results often cannot be directly transferred to humans additionally shifts the focus towards cell-based assays. This current trend triggers the development of more sophisticated laser-based techniques to manipulate and investigate cells. In this rapidly changing field, it is nearly impossible to provide a comprehensive view of all available techniques, since new techniques are constantly developed on nearly a weekly basis. In this chapter, we have made an effort to provide the physical basis for laser-based cell manipulation, complemented by several of the more exceptional applications of optical cell manipulation.

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