Cloud-based deep learning of big EEG data for epileptic seizure prediction

Developing a Brain-Computer Interface (BCI) for seizure prediction can help epileptic patients have a better quality of life. However, there are many difficulties and challenges in developing such a system as a real-life support for patients. Because of the nonstationary nature of EEG signals, normal and seizure patterns vary across different patients. Thus, finding a group of manually extracted features for the prediction task is not practical. Moreover, when using implanted electrodes for brain recording massive amounts of data are produced. This big data calls for the need for safe storage and high computational resources for real-time processing. To address these challenges, a cloud-based BCI system for the analysis of this big EEG data is presented. First, a dimensionality-reduction technique is developed to increase classification accuracy as well as to decrease the communication bandwidth and computation time. Second, following a deep-learning approach, a stacked autoencoder is trained in two steps for unsupervised feature extraction and classification. Third, a cloud-computing solution is proposed for real-time analysis of big EEG data. The results on a benchmark clinical dataset illustrate the superiority of the proposed patient-specific BCI as an alternative method and its expected usefulness in real-life support of epilepsy patients.

[1]  Hamid Soltanian-Zadeh,et al.  Three cuts method for identification of COPD. , 2013, Acta medica Iranica.

[3]  Joost B. Wagenaar,et al.  Forecasting Seizures Using Intracranial EEG Measures and SVM in Naturally Occurring Canine Epilepsy , 2015, PloS one.

[4]  Liu Liu,et al.  Deep tree-structured face: A unified representation for multi-task facial biometrics , 2016, 2016 IEEE Winter Conference on Applications of Computer Vision (WACV).

[5]  Hosseini Mohammad Parsa,et al.  Designing a new CAD system for pulmonary nodule detection in High Resolution Computed Tomography (HRCT) images , 2012 .

[6]  Hosseini Mohammad Parsa,et al.  COMPUTER- AIDED DIAGNOSIS SYSTEM FOR THE EVALUATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ON CT IMAGES , 2011 .

[7]  George Atia,et al.  Randomized Robust Subspace Recovery and Outlier Detection for High Dimensional Data Matrices , 2015, IEEE Transactions on Signal Processing.

[8]  Ning Wang,et al.  Extracting and Selecting Distinctive EEG Features for Efficient Epileptic Seizure Prediction , 2015, IEEE Journal of Biomedical and Health Informatics.

[9]  Hui-Chuan Wu,et al.  Classification Preictal and Interictal Stages via Integrating Interchannel and Time-Domain Analysis of EEG Features , 2017, Clinical EEG and neuroscience.

[10]  Zoubin Ghahramani,et al.  Infinite Sparse Factor Analysis and Infinite Independent Components Analysis , 2007, ICA.

[11]  Benjamin H. Brinkmann,et al.  Large-scale electrophysiology: Acquisition, compression, encryption, and storage of big data , 2009, Journal of Neuroscience Methods.

[12]  Hamid Soltanian-Zadeh,et al.  Support Vector Machine with nonlinear-kernel optimization for lateralization of epileptogenic hippocampus in MR images , 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[13]  Mohammad Parsa Hosseini Proposing a new artificial intelligent system for automatic detection of Epileptic seizures , 2015 .

[14]  Dario Pompili,et al.  Automatic and Manual Segmentation of Hippocampus in Epileptic Patients MRI , 2016, ArXiv.

[15]  Dario Pompili,et al.  Comparative performance evaluation of automated segmentation methods of hippocampus from magnetic resonance images of temporal lobe epilepsy patients. , 2016, Medical physics.

[16]  Mahdieh Soleymani Baghshah,et al.  PSSDL: Probabilistic Semi-supervised Dictionary Learning , 2013, ECML/PKDD.

[17]  Shervin Minaee,et al.  Screen content image segmentation using least absolute deviation fitting , 2015, 2015 IEEE International Conference on Image Processing (ICIP).

[18]  Guoping Zhang,et al.  Novel images extraction model using improved delay vector variance feature extraction and multi-kernel neural network for EEG detection and prediction. , 2015, Technology and health care : official journal of the European Society for Engineering and Medicine.

[19]  Keshab K. Parhi,et al.  Low-Complexity Seizure Prediction From iEEG/sEEG Using Spectral Power and Ratios of Spectral Power , 2016, IEEE Transactions on Biomedical Circuits and Systems.

[20]  George Atia,et al.  A Subspace Learning Approach for High Dimensional Matrix Decomposition with Efficient Column/Row Sampling , 2016, ICML.

[21]  Hamid Soltanian-Zadeh,et al.  Detection and Severity Scoring of Chronic Obstructive Pulmonary Disease Using Volumetric Analysis of Lung CT Images , 2012, Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society.

[22]  George Atia,et al.  Randomized Robust Subspace Recovery for High Dimensional Data Matrices , 2015, ArXiv.

[23]  Hamid Soltanian-Zadeh,et al.  7990 Lateralization of Temporal Lobe Epilepsy using Intrinsic Property of Water Diffusion in Fornix Crus , 2013 .

[24]  Nazanin Rahnavard,et al.  Union of low-rank subspaces detector , 2013, IET Signal Process..

[25]  Yu-Te Wang,et al.  Pervasive brain monitoring and data sharing based on multi-tier distributed computing and linked data technology , 2014, Front. Hum. Neurosci..

[26]  Fariborz Mahmoudi,et al.  Lateralization of temporal lobe epilepsy by imaging-based response-driven multinomial multivariate models , 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[27]  Dario Pompili,et al.  Real-Time Epileptic Seizure Detection from EEG Signals via Random Subspace Ensemble Learning , 2016, 2016 IEEE International Conference on Autonomic Computing (ICAC).

[28]  Dario Pompili,et al.  Statistical validation of automatic methods for hippocampus segmentation in MR images of epileptic patients , 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[29]  Gang Wang,et al.  Deep Learning-Based Classification of Hyperspectral Data , 2014, IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing.

[30]  Shervin Minaee,et al.  Fingerprint recognition using translation invariant scattering network , 2015, 2015 IEEE Signal Processing in Medicine and Biology Symposium (SPMB).