An RNA-sequencing transcriptome of the rodent Schwann cell response to peripheral nerve injury

[1]  P. Kharchenko,et al.  Diversity of developing peripheral glia revealed by single-cell RNA sequencing. , 2021, Developmental cell.

[2]  A. Ishii,et al.  Mek/ERK1/2‐MAPK and PI3K/Akt/mTOR signaling plays both independent and cooperative roles in Schwann cell differentiation, myelination and dysmyelination , 2021, Glia.

[3]  Tao Wang,et al.  Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway , 2021, Journal of neuroinflammation.

[4]  U. Suter,et al.  Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT) , 2021, eLife.

[5]  Edmund R Hollis,et al.  Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement , 2020, bioRxiv.

[6]  T. Südhof,et al.  SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins , 2020, The Journal of Neuroscience.

[7]  Sean M. Riordan,et al.  RNA Sequencing of Human Peripheral Nerve in Response to Injury: Distinctive Analysis of the Nerve Repair Pathways , 2020, Cell transplantation.

[8]  Qifu Li,et al.  Regulation of SPARC family proteins in disorders of the central nervous system , 2020, Brain Research Bulletin.

[9]  B. Knöll,et al.  Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury , 2020, Nature Communications.

[10]  D. Kaplan,et al.  Peripheral Nerve Single-Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth , 2020, eNeuro.

[11]  H. Wiendl,et al.  Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity , 2020, Proceedings of the National Academy of Sciences.

[12]  L. Egaña-Gorroño,et al.  Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models , 2020, Frontiers in Cardiovascular Medicine.

[13]  A. Korobeynikov,et al.  Sequence Analysis , 2020, Encyclopedia of Bioinformatics and Computational Biology.

[14]  Osman Ugur Sezerman,et al.  pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks , 2019, Front. Genet..

[15]  K. Jessen,et al.  Repair Schwann cell update: Adaptive reprogramming, EMT, and stemness in regenerating nerves , 2019, Glia.

[16]  Jian Qi,et al.  Analysis of transcriptome sequencing of sciatic nerves in Sprague-Dawley rats of different ages , 2018, Neural regeneration research.

[17]  A. Schmidt,et al.  The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases , 2017, Front. Genet..

[18]  D. Nosi,et al.  Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice , 2017, Nature Communications.

[19]  R. Mirsky,et al.  After Nerve Injury, Lineage Tracing Shows That Myelin and Remak Schwann Cells Elongate Extensively and Branch to Form Repair Schwann Cells, Which Shorten Radically on Remyelination , 2017, The Journal of Neuroscience.

[20]  R. Mirsky,et al.  Changes in the Coding and Non-coding Transcriptome and DNA Methylome that Define the Schwann Cell Repair Phenotype after Nerve Injury , 2017, Cell reports.

[21]  U. Suter,et al.  Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system , 2017, eLife.

[22]  J. Zuchero,et al.  Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury , 2017, Proceedings of the National Academy of Sciences.

[23]  P. Ambros,et al.  Proteomics and transcriptomics of peripheral nerve tissue and cells unravel new aspects of the human Schwann cell repair phenotype , 2016, Glia.

[24]  Youhua Wang,et al.  Sam68 promotes Schwann cell proliferation by enhancing the PI3K/Akt pathway and acts on regeneration after sciatic nerve crush. , 2016, Biochemical and biophysical research communications.

[25]  R. Mirsky,et al.  The repair Schwann cell and its function in regenerating nerves , 2016, The Journal of physiology.

[26]  E. Chang,et al.  Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse , 2016, Neuron.

[27]  Bin Yu,et al.  Deep Sequencing and Bioinformatic Analysis of Lesioned Sciatic Nerves after Crush Injury , 2015, PloS one.

[28]  F. Baas,et al.  Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves , 2015, The Journal of cell biology.

[29]  A. B. Lutz.  Purification of Schwann cells. , 2014, Cold Spring Harbor protocols.

[30]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[31]  Christine M. Miller,et al.  Diminished Schwann Cell Repair Responses Underlie Age-Associated Impaired Axonal Regeneration , 2014, Neuron.

[32]  L. Greensmith,et al.  c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration , 2012, Neuron.

[33]  Peter Langfelder,et al.  Fast R Functions for Robust Correlations and Hierarchical Clustering. , 2012, Journal of statistical software.

[34]  Ashwin Woodhoo,et al.  A Central Role for the ERK-Signaling Pathway in Controlling Schwann Cell Plasticity and Peripheral Nerve Regeneration In Vivo , 2012, Neuron.

[35]  D. Geschwind,et al.  Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice. , 2011, The Journal of clinical investigation.

[36]  P. Popovich,et al.  Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury , 2011, Journal of Neuroinflammation.

[37]  Colin N. Dewey,et al.  RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome , 2011, BMC Bioinformatics.

[38]  B. Barres,et al.  Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC , 2011, Proceedings of the National Academy of Sciences.

[39]  D. Geschwind,et al.  Specific Functions for ERK/MAPK Signaling during PNS Development , 2011, Neuron.

[40]  C. Mermelstein,et al.  Sciatic nerve regeneration is accelerated in galectin-3 knockout mice , 2009, Experimental Neurology.

[41]  Rhona Mirsky,et al.  Negative regulation of myelination: Relevance for development, injury, and demyelinating disease , 2008, Glia.

[42]  R. Wada,et al.  Role of Advanced Glycation End Products and Their Receptors in Development of Diabetic Neuropathy , 2005, Annals of the New York Academy of Sciences.

[43]  W. Mandemakers,et al.  An Oligodendrocyte Lineage-Specific Semaphorin, Sema5A, Inhibits Axon Growth by Retinal Ganglion Cells , 2004, The Journal of Neuroscience.

[44]  J. Milbrandt,et al.  Deciphering peripheral nerve myelination by using Schwann cell expression profiling , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[45]  M. Baker.  Electrophysiology of mammalian Schwann cells. , 2002, Progress in biophysics and molecular biology.

[46]  Ann Saada,et al.  Peripheral nerve injury induces Schwann cells to express two macrophage phenotypes: phagocytosis and the galactose-specific lectin MAC-2 , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[47]  R. Mirsky,et al.  Schwann cells: Early lineage, regulation of proliferation and control of myelin formation , 1992, Current Biology.

[48]  G. Wilson,et al.  Ion channels in axon and Schwann cell membranes at paranodes of mammalian myelinated fibers studied with patch clamp , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[49]  Xianrang Song,et al.  Maturation of a central , 1996 .