Molecular Pathology: Predictive, Prognostic, and Diagnostic Markers in Salivary Gland Tumors.

[1]  R. Weber,et al.  Role of CRTC1/MAML2 Translocation in the Prognosis and Clinical Outcomes of Mucoepidermoid Carcinoma. , 2016, JAMA otolaryngology-- head & neck surgery.

[2]  T. Vaněček,et al.  Mammary Analogue Secretory Carcinoma of Salivary Glands: Molecular Analysis of 25 ETV6 Gene Rearranged Tumors With Lack of Detection of Classical ETV6-NTRK3 Fusion Transcript by Standard RT-PCR: Report of 4 Cases Harboring ETV6-X Gene Fusion , 2016, The American journal of surgical pathology.

[3]  Sung-Bae Kim,et al.  Phase 2 study of dovitinib in patients with metastatic or unresectable adenoid cystic carcinoma , 2015, Cancer.

[4]  Simion I. Chiosea,et al.  Molecular Characterization of Apocrine Salivary Duct Carcinoma , 2015, The American journal of surgical pathology.

[5]  M. Matsumoto,et al.  Mammary Analogue Secretory Carcinoma of Salivary Glands: A Clinicopathologic and Molecular Study Including 2 Cases Harboring ETV6-X Fusion , 2015, The American journal of surgical pathology.

[6]  Simion I. Chiosea,et al.  Salivary Duct Carcinoma: The Predominance of Apocrine Morphology, Prevalence of Histologic Variants, and Androgen Receptor Expression , 2015, The American journal of surgical pathology.

[7]  A. Agaimy,et al.  Clear Cell Myoepithelial Carcinoma of Salivary Glands Showing EWSR1 Rearrangement: Molecular Analysis of 94 Salivary Gland Carcinomas With Prominent Clear Cell Component , 2015, The American journal of surgical pathology.

[8]  R. Seethala,et al.  A comparative analysis of LEF-1 in odontogenic and salivary tumors. , 2015, Human pathology.

[9]  T. Nagao,et al.  Clinicopathological significance of androgen receptor, HER2, Ki-67 and EGFR expressions in salivary duct carcinoma , 2015, International Journal of Clinical Oncology.

[10]  S. Dogan,et al.  Prognostic features in mucoepidermoid carcinoma of major salivary glands with emphasis on tumour histologic grading , 2014, Histopathology.

[11]  M. Fujii,et al.  Clinicopathologic study of salivary duct carcinoma and the efficacy of androgen deprivation therapy. , 2014, American journal of otolaryngology.

[12]  Simion I. Chiosea,et al.  Novel PRKD gene rearrangements and variant fusions in cribriform adenocarcinoma of salivary gland origin , 2014, Genes, chromosomes & cancer.

[13]  Simion I. Chiosea,et al.  Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands , 2014, Nature Genetics.

[14]  M. Hermsen,et al.  Analysis of MYB oncogene in transformed adenoid cystic carcinomas reveals distinct pathways of tumor progression , 2014, Laboratory Investigation.

[15]  Simion I. Chiosea,et al.  HRAS Mutations in Epithelial–Myoepithelial Carcinoma , 2014, Head and Neck Pathology.

[16]  A. Franchi,et al.  Diagnostic Utility of PLAG1 Immunohistochemical Determination in Salivary Gland Tumors , 2014, Applied immunohistochemistry & molecular morphology : AIMM.

[17]  S. Lippman,et al.  Human epidermal receptor 2–amplified salivary duct carcinoma: Regression with dual human epidermal receptor 2 inhibition and anti–vascular endothelial growth factor combination treatment , 2014, Head & neck.

[18]  L. Thompson,et al.  Definitive treatment of androgen receptor–positive salivary duct carcinoma with androgen deprivation therapy and external beam radiotherapy , 2014, Head & neck.

[19]  J. Roh,et al.  Basal cell adenocarcinoma of the salivary gland: a morphological and immunohistochemical comparison with basal cell adenoma with and without capsular invasion , 2013, Diagnostic Pathology.

[20]  P. Laurent-Puig,et al.  Expression and mutational status of treatment-relevant targets and key oncogenes in 123 malignant salivary gland tumours. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.

[21]  Simion I. Chiosea,et al.  PIK3CA Mutations and PTEN Loss in Salivary Duct Carcinomas , 2013, The American journal of surgical pathology.

[22]  M. Stratton,et al.  Whole exome sequencing of adenoid cystic carcinoma. , 2013, The Journal of clinical investigation.

[23]  C. Antonescu,et al.  Clear Cell Odontogenic Carcinomas Show EWSR1 Rearrangements: A Novel Finding and a Biological Link to Salivary Clear Cell Carcinomas , 2013, The American journal of surgical pathology.

[24]  T. Nagao.  “Dedifferentiation” and High-Grade Transformation in Salivary Gland Carcinomas , 2013, Head and Neck Pathology.

[25]  Benjamin J. Raphael,et al.  The Mutational Landscape of Adenoid Cystic Carcinoma , 2013, Nature Genetics.

[26]  R. Tishler,et al.  Trastuzumab for the treatment of salivary duct carcinoma. , 2013, The oncologist.

[27]  S. Knuutila,et al.  Genomic profiles and CRTC1–MAML2 fusion distinguish different subtypes of mucoepidermoid carcinoma , 2013, Modern Pathology.

[28]  Julie M. Batten,et al.  Detection of Novel Actionable Genetic Changes in Salivary Duct Carcinoma Helps Direct Patient Treatment , 2012, Clinical Cancer Research.

[29]  J. Reis-Filho,et al.  Salivary duct carcinomas can be classified into luminal androgen receptor‐positive, HER2 and basal‐like phenotypes * , 2012, Histopathology.

[30]  P. A. Futreal,et al.  Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma , 2012, Genes, chromosomes & cancer.

[31]  Simion I. Chiosea,et al.  Prospective testing of mucoepidermoid carcinoma for the MAML2 translocation: Clinical Implications , 2012, The Laryngoscope.

[32]  A. Bahrami,et al.  PLAG1 Alteration in Carcinoma Ex Pleomorphic Adenoma: Immunohistochemical and Fluorescence In Situ Hybridization Studies of 22 Cases , 2012, Head and Neck Pathology.

[33]  R. Seethala,et al.  Fluorescence in situ hybridization for detection of MAML2 rearrangements in oncocytic mucoepidermoid carcinomas: utility as a diagnostic test. , 2011, Human pathology.

[34]  P. A. Futreal,et al.  Novel Chromosomal Rearrangements and Break Points at the t(6;9) in Salivary Adenoid Cystic Carcinoma: Association with MYB–NFIB Chimeric Fusion, MYB Expression, and Clinical Outcome , 2011, Clinical Cancer Research.

[35]  C. Moskaluk,et al.  Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms , 2011, Modern Pathology.

[36]  G. Sauter,et al.  Human epidermal growth factor receptor 2 (HER2) in salivary gland carcinomas , 2011, Pathology.

[37]  Kazutaka Nakashima,et al.  Nuclear β-catenin expression in basal cell adenomas of salivary gland. , 2011, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[38]  C. Antonescu,et al.  EWSR1‐ATF1 fusion is a novel and consistent finding in hyalinizing clear‐cell carcinoma of salivary gland , 2011, Genes, chromosomes & cancer.

[39]  H. Hashimoto,et al.  Aberrant PLAG1 expression in pleomorphic adenomas of the salivary gland: a molecular genetic and immunohistochemical study , 2011, Virchows Archiv.

[40]  T. Ettl,et al.  Salivary gland mucoepidermoid carcinoma is a clinically, morphologically and genetically heterogeneous entity: a clinicopathological study of 40 cases with emphasis on grading, histological variants and presence of the t(11;19) translocation , 2011, Histopathology.

[41]  R. West,et al.  MYB Expression and Translocation in Adenoid Cystic Carcinomas and Other Salivary Gland Tumors With Clinicopathologic Correlation , 2011, The American journal of surgical pathology.

[42]  R. Weber,et al.  Comprehensive Analysis of the MYB-NFIB Gene Fusion in Salivary Adenoid Cystic Carcinoma: Incidence, Variability, and Clinicopathologic Significance , 2010, Clinical Cancer Research.

[43]  R. Seethala,et al.  A Reappraisal of the MECT1/MAML2 Translocation in Salivary Mucoepidermoid Carcinomas , 2010, The American journal of surgical pathology.

[44]  B. Perez-Ordonez,et al.  Mammary Analogue Secretory Carcinoma of Salivary Glands, Containing the ETV6-NTRK3 Fusion Gene: A Hitherto Undescribed Salivary Gland Tumor Entity , 2010, The American journal of surgical pathology.

[45]  P. Meltzer,et al.  Unfavorable prognosis of CRTC1‐MAML2 positive mucoepidermoid tumors with CDKN2A deletions , 2010, Genes, chromosomes & cancer.

[46]  R. Seethala.  An Update on Grading of Salivary Gland Carcinomas , 2009, Head and neck pathology.

[47]  F. Persson,et al.  High‐resolution genomic profiling of adenomas and carcinomas of the salivary glands reveals amplification, rearrangement, and fusion of HMGA2 , 2009, Genes, chromosomes & cancer.

[48]  Jörn Bullerdiek,et al.  A new type of MAML2 fusion in mucoepidermoid carcinoma , 2008, Genes, chromosomes & cancer.

[49]  J. Mark,et al.  Chromosomal patterns in a benign human neoplasm, the mixed salivary gland tumour. , 2008, Hereditas.

[50]  R. Seethala,et al.  Adenoid Cystic Carcinoma With High-grade Transformation: A Report of 11 Cases and a Review of the Literature , 2007, The American journal of surgical pathology.

[51]  M. Luna.  Salivary Mucoepidermoid Carcinoma: Revisited , 2006, Advances in anatomic pathology.

[52]  Shigeo Nakamura,et al.  MECT1-MAML2 Fusion Transcript Defines a Favorable Subset of Mucoepidermoid Carcinoma , 2006, Clinical Cancer Research.

[53]  L. Szekely,et al.  Molecular classification of mucoepidermoid carcinomas—Prognostic significance of the MECT1–MAML2 fusion oncogene , 2006, Genes, chromosomes & cancer.

[54]  G. Tonon,et al.  t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway , 2003, Nature Genetics.

[55]  J. Batsakis,et al.  Molecular Analysis of Chromosome 16q Regions in Dermal Analogue Tumors of Salivary Glands: A Genetic Link to Dermal Cylindroma? , 2002, The American journal of surgical pathology.

[56]  E. Barnes,et al.  Expression of androgen receptor and prostatic specific markers in salivary duct carcinoma: an immunohistochemical analysis of 13 cases and review of the literature. , 2000, The American journal of surgical pathology.

[57]  H. Gustafsson,et al.  Non‐random chromosome rearrangements in adenoid cystic carcinoma of the salivary glands , 1994, Genes, chromosomes & cancer.

[58]  H. Gustafsson,et al.  Recurrent rearrangements of 11q14-22 in mucoepidermoid carcinoma. , 1994, Cancer genetics and cytogenetics.

[59]  J. Bullerdiek,et al.  Cytogenetic investigations on a cell line derived from a carcinoma arising in a salivary gland pleomorphic adenoma. , 1990, Cancer genetics and cytogenetics.

[60]  C. Antonescu,et al.  Consistent PLAG1 and HMGA2 abnormalities distinguish carcinoma ex-pleomorphic adenoma from its de novo counterparts. , 2015, Human pathology.

[61]  Simion I. Chiosea,et al.  Clinicopathological characterization of mammary analogue secretory carcinoma of salivary glands , 2012, Histopathology.

[62]  Y. Hasegawa,et al.  Clinicopathological significance of the CRTC3–MAML2 fusion transcript in mucoepidermoid carcinoma , 2009, Modern Pathology.

[63]  J. Haubrich,et al.  Cytogenetic subtyping of 220 salivary gland pleomorphic adenomas: correlation to occurrence, histological subtype, and in vitro cellular behavior. , 1993, Cancer genetics and cytogenetics.

[64]  J. Mark,et al.  Relationships between chromosomal patterns and protooncogenes in human benign salivary gland tumors. , 1984, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.