Solubility of pioglitazone hydrochloride in binary mixtures of polyethylene glycol 400 with ethanol, propylene glycol, N-methyl-2-pyrrolidone, and water at 25 degrees C.

The solubility of pioglitazone hydrochloride in binary mixtures of polyethylene glycol 400 with ethanol, N-methyl-2-pyrrolidone, propylene glycol, and water at 25 degrees C are reported. The generated data are fitted to the Jouyban-Acree model and the mean relative deviations are 2.6%, 1.5%, 5.8%, and 7.4%, respectively for ethanol, N-methyl-2-pyrrolidone, propylene glycol, and water.

[1]  Abolghasem Jouyban,et al.  Handbook of Solubility Data for Pharmaceuticals , 2009 .

[2]  A. Nokhodchi,et al.  Solubility of Chlordiazepoxide, Diazepam, and Lorazepam in Ethanol + Water Mixtures at 303.2 K , 2009 .

[3]  A. Florence,et al.  Room temperature ionic liquids and their mixtures: potential pharmaceutical solvents. , 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[4]  A. Jain.  Solubilization of indomethacin using hydrotropes for aqueous injection. , 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[5]  Abu T M Serajuddin,et al.  Salt formation to improve drug solubility. , 2007, Advanced drug delivery reviews.

[6]  V. Stella,et al.  Prodrug strategies to overcome poor water solubility. , 2007, Advanced drug delivery reviews.

[7]  P York,et al.  Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. , 2007, Advanced drug delivery reviews.

[8]  S. Yalkowsky,et al.  Stacking complexation by nicotinamide: a useful way of enhancing drug solubility. , 2007, International journal of pharmaceutics.

[9]  Hongkun Zhao,et al.  Solubility of anthracene in N,N-dimethyformamide, N,N -dimethylacetamide, and N-methyl -2 -pyrrolidone , 2007 .

[10]  A. Jouyban.  Solubility prediction of drugs in water-polyethylene glycol 400 mixtures using Jouyban-acree model. , 2006, Chemical & pharmaceutical bulletin.

[11]  Yasuo Ida,et al.  Solubilization behavior of a poorly soluble drug under combined use of surfactants and cosolvents. , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[12]  R. Strickley.  Solubilizing Excipients in Oral and Injectable Formulations , 2004, Pharmaceutical Research.

[13]  E. Ruckenstein,et al.  Solubility of drugs in aqueous solutions. Part 2: binary nonideal mixed solvent. , 2003, International journal of pharmaceutics.

[14]  T. Radhakrishna,et al.  Determination of pioglitazone hydrochloride in bulk and pharmaceutical formulations by HPLC and MEKC methods. , 2002, Journal of pharmaceutical and biomedical analysis.

[15]  M. Barzegar-Jalali,et al.  Comparison of various cosolvency models for calculating solute solubility in water-cosolvent mixtures. , 1999, International journal of pharmaceutics.

[16]  M. Barzegar-Jalali,et al.  Solubility correlation of structurally related drugs in binary solvent mixtures , 1998 .

[17]  S. Yalkowsky,et al.  Solubilization by cosolvents I: organic solutes in propylene glycol-water mixtures. , 1985, Journal of pharmaceutical sciences.

[18]  Qinbo Wang,et al.  Solubilities of 4-Carboxybenzaldehyde and 1,4-Benzenedicarboxylic Acid in N-Methyl-2-pyrrolidone in the Temperature Range from (343.2 to 468.2) K , 2005 .

[19]  S. Yalkowsky,et al.  Handbook of aqueous solubility data , 2003 .