Genotype‐phenotype correlation of CTNNB1 mutations reveals different ß‐catenin activity associated with liver tumor progression
暂无分享,去创建一个
S. Imbeaud | J. Zucman‐Rossi | E. Letouzé | J. Calderaro | S. Rebouissou | C. Balabaud | P. Bioulac-Sage | G. Couchy | J. Nault | A. Laurent | C. Pilati | A. Franconi
[1] J. Zucman‐Rossi,et al. Genetic Landscape and Biomarkers of Hepatocellular Carcinoma. , 2015, Gastroenterology.
[2] L. Terracciano,et al. Nrf2, but not β‐catenin, mutation represents an early event in rat hepatocarcinogenesis , 2015, Hepatology.
[3] L. Qin,et al. β-catenin mutation is correlated with a favorable prognosis in patients with hepatocellular carcinoma. , 2015, Molecular and clinical oncology.
[4] Jessica Zucman-Rossi,et al. Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets , 2015, Nature Genetics.
[5] A. Zell,et al. Dysregulated serum response factor triggers formation of hepatocellular carcinoma , 2015, Hepatology.
[6] J. Zucman‐Rossi,et al. Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis , 2014, Hepatology.
[7] Jessica Zucman-Rossi,et al. Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation. , 2014, Cancer cell.
[8] J. Calderaro,et al. High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions , 2013, Nature Communications.
[9] S. Imbeaud,et al. A hepatocellular carcinoma 5-gene score associated with survival of patients after liver resection. , 2013, Gastroenterology.
[10] Jessica Zucman-Rossi,et al. Hepatocellular benign tumors-from molecular classification to personalized clinical care. , 2013, Gastroenterology.
[11] S. Imbeaud,et al. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma , 2012, Nature Genetics.
[12] J. Zucman‐Rossi,et al. Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas , 2011, The Journal of experimental medicine.
[13] E. Kuipers,et al. Colorectal Cancers Choosing Sides , 2011 .
[14] Y. Jeng,et al. Role of p53 and β-catenin Mutations in Conjunction with CK19 Expression on Early Tumor Recurrence and Prognosis of Hepatocellular Carcinoma , 2011, Journal of Gastrointestinal Surgery.
[15] C. Dai,et al. Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine‐45 mutant β‐catenin , 2010, Hepatology.
[16] B. Cieply,et al. Unique phenotype of hepatocellular cancers with exon‐3 mutations in beta‐catenin gene , 2009, Hepatology.
[17] S. Imbeaud,et al. Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours , 2009, Nature.
[18] Yu Wei,et al. Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. , 2008, Cancer cell.
[19] T. Lister,et al. Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia. , 2008, Blood.
[20] Rolf Gebhardt,et al. Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma , 2008, Molecular Cancer.
[21] Cristel G. Thomas,et al. Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry , 2007, Hepatology.
[22] C. Elie,et al. Cholestasis is a marker for hepatocellular carcinomas displaying β‐catenin mutations , 2007, The Journal of pathology.
[23] S. Boyault,et al. Differential effects of inactivated Axin1 and activated β-catenin mutations in human hepatocellular carcinomas , 2007, Oncogene.
[24] S. Boyault,et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets , 2007, Hepatology.
[25] J. Zucman‐Rossi,et al. Genotype–phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC , 2006, Hepatology.
[26] T. A. Lister,et al. Association between acquired uniparental disomy and homozygous gene mutation in acute myeloid leukemias. , 2005, Cancer research.
[27] Mario Cazzola,et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. , 2005, The New England journal of medicine.
[28] K. Kinzler,et al. Phosphorylation of β-Catenin at S33, S37, or T41 Can Occur in the Absence of Phosphorylation at T45 in Colon Cancer Cells , 2003 .
[29] J. Zucman‐Rossi,et al. Bi-allelic inactivation of TCF1 in hepatic adenomas , 2002, Nature Genetics.
[30] R. Fodde,et al. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade. , 2002, Human molecular genetics.
[31] Matthias Mann,et al. Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. , 2002, Genes & development.
[32] Xi He,et al. Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism , 2002, Cell.
[33] A. Buchmann,et al. Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of β-catenin-mutated mouse liver tumors , 2001, Oncogene.
[34] G. Thomas,et al. Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis. , 2001, Gastroenterology.
[35] I. Lubensky,et al. Duplication of the mutant RET allele in trisomy 10 or loss of the wild-type allele in multiple endocrine neoplasia type 2-associated pheochromocytomas. , 2000, Cancer research.
[36] M. Evans,et al. Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators. , 2000, Molecular biology of the cell.
[37] Y. Jeng,et al. Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis. , 2000, The American journal of pathology.
[38] Sabine Tejpar,et al. Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor) , 1999, Oncogene.
[39] Ian Tomlinson,et al. The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis , 1999, Nature Medicine.
[40] W. Marston Linehan,et al. Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas , 1998, Nature Genetics.
[41] M. Buendia,et al. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[42] S. Lowe,et al. Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a , 1997, Cell.
[43] A. Knudson. Mutation and cancer: statistical study of retinoblastoma. , 1971, Proceedings of the National Academy of Sciences of the United States of America.
[44] A. Hope. A Simplified Monte Carlo Significance Test Procedure , 1968 .
[45] J. Tran van Nhieu,et al. GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation. , 2012, Journal of hepatology.
[46] Xi He,et al. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. , 2002, Cell.
[47] Jan Kitajewski,et al. New targets of β-catenin signaling in the liver are involved in the glutamine metabolism , 2002, Oncogene.