Induction of quinone reductase as a primary screen for natural product anticarcinogens.
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[1] J. Pezzuto,et al. Cancer Chemopreventive Agents Discovered by Activity-Guided Fractionation: An Update , 2003 .
[2] J. Pezzuto,et al. Discovery of cancer preventive agents from natural products: From plants to prevention , 2002, Current oncology reports.
[3] J. Pezzuto,et al. Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase. , 2002, Journal of natural products.
[4] Kelly E Heim,et al. Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships. , 2002, The Journal of nutritional biochemistry.
[5] E. Rimm,et al. Flavonol and flavone intakes in US health professionals. , 2002, Journal of the American Dietetic Association.
[6] A. Kong,et al. Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes. , 2002, Current drug metabolism.
[7] J. Pezzuto,et al. Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase. , 2002, Journal of agricultural and food chemistry.
[8] R. Cole,et al. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[9] J. Pezzuto,et al. New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes. , 2002, Journal of natural products.
[10] J. Pezzuto,et al. Bioactive Constituents of the Seeds of Brucea javanica , 2002, Planta medica.
[11] L. Marchand. Cancer preventive effects of flavonoids—a review , 2002 .
[12] Y. Uda,et al. In vitro induction of the anticarcinogenic marker enzyme, quinone reductase, in human hepatoma cells by food extracts. , 2002, Cancer letters.
[13] John M Pezzuto,et al. Induction of quinone reductase by withanolides. , 2002, Journal of natural products.
[14] J. Pezzuto,et al. Isolation and characterization of bioactive principles of the leaves and stems of Physalis philadelphica , 2002 .
[15] Anna-Sigrid Keck,et al. The Cruciferous Nitrile Crambene Has Bioactivity Similar to Sulforaphane When Administered to Fischer 344 Rats but Is Far Less Potent in Cell Culture , 2002, Nutrition and cancer.
[16] L. Jeong,et al. Induction of quinone reductase activity by stilbene analogs in mouse hepa 1c1c7 cells , 2001, Archives of pharmacal research.
[17] J. Pezzuto,et al. Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture. , 2001, Journal of natural products.
[18] Y. Surh,et al. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. , 2001, Mutation research.
[19] D. Guyonnet,et al. Antimutagenic activity of organosulfur compounds from Allium is associated with phase II enzyme induction. , 2001, Mutation research.
[20] V. Steele,et al. Induction of atypical ductal hyperplasia in mouse mammary gland organ culture. , 2001, Journal of the National Cancer Institute.
[21] E. Jeffery,et al. The synergistic upregulation of phase II detoxification enzymes by glucosinolate breakdown products in cruciferous vegetables. , 2001, Toxicology and applied pharmacology.
[22] S. Jee,et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. , 2001, Anticancer research.
[23] A. Wolk,et al. Brassica vegetables and breast cancer risk. , 2001, JAMA.
[24] T. Shapiro,et al. Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[25] R. Munday,et al. Relative Activities of Organosulfur Compounds Derived From Onions and Garlic in Increasing Tissue Activities of Quinone Reductase and Glutathione Transferase in Rat Tissues , 2001, Nutrition and cancer.
[26] F. Kauffman,et al. Challenges of cancer drug design: a drug metabolism perspective. , 2001, Current cancer drug targets.
[27] L. Holmberg,et al. Fruit, vegetables, dietary fiber, and risk of colorectal cancer. , 2001, Journal of the National Cancer Institute.
[28] P. Talalay,et al. The Importance of Using Scientific Principles in the Development of Medicinal Agents from Plants , 2001, Academic medicine : journal of the Association of American Medical Colleges.
[29] M. Kwak,et al. Role of Transcription Factor Nrf2 in the Induction of Hepatic Phase 2 and Antioxidative Enzymes in vivo by the Cancer Chemoprotective Agent, 3H-1, 2-Dithiole-3-thione , 2001 .
[30] D. Ross,et al. NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms. , 2000, Chemico-biological interactions.
[31] M. A. V. Van Duyn,et al. Overview of the health benefits of fruit and vegetable consumption for the dietetics professional: selected literature. , 2000, Journal of the American Dietetic Association.
[32] C. Gerhäuser,et al. New lanostanoids from Ganoderma lucidum that induce NAD(P)H:quinone oxidoreductase in cultured hepalcic7 murine hepatoma cells. , 2000, Planta medica.
[33] M. Spitz,et al. Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk. , 2000, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[34] E. Rosen,et al. Inhibitory effects of Indole-3-carbinol on invasion and migration in human breast cancer cells , 2000, Breast Cancer Research and Treatment.
[35] P. Gutiérrez. The role of NAD(P)H oxidoreductase (DT-Diaphorase) in the bioactivation of quinone-containing antitumor agents: a review. , 2000, Free radical biology & medicine.
[36] J. Pezzuto,et al. Bioactive constituents of Thuja occidentalis. , 2000, Journal of natural products.
[37] F. Speizer,et al. Intakes of fruits, vegetables, and related nutrients and the risk of non-Hodgkin's lymphoma among women. , 2000, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[38] J. Pezzuto,et al. Absolute configuration of novel bioactive flavonoids from Tephrosia purpurea. , 2000, Organic letters.
[39] C. Sigman,et al. Cancer chemoprevention: progress and promise. , 1999, European journal of cancer.
[40] M. Iwu,et al. Anti-plasmodial sesquiterpenoids from the African Reneilmia cincinnata. , 1999, Phytochemistry.
[41] M. Sporn,et al. Prevention of cancer in the next millennium: Report of the Chemoprevention Working Group to the American Association for Cancer Research. , 1999, Cancer research.
[42] M. Osborne,et al. Multifunctional Aspects of the Action of Indole‐3‐Carbinol as an Antitumor Agent , 1999, Annals of the New York Academy of Sciences.
[43] Y. Surh,et al. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. , 1999, Mutation research.
[44] A. Dinkova-Kostova,et al. Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes. , 1999, Carcinogenesis.
[45] H. Bradlow,et al. Anti-estrogenic activities of indole-3-carbinol in cervical cells: implication for prevention of cervical cancer. , 1999, Anticancer research.
[46] E. Rimm,et al. Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort. , 1999, Journal of the National Cancer Institute.
[47] K. Hostettmann,et al. Chemistry, Biological and Pharmacological Properties of Medicinal Plants from the Americas , 1999 .
[48] J. Pezzuto,et al. Cancer chemopreventive activity mediated by 4'-bromoflavone, a potent inducer of phase II detoxification enzymes. , 1999, Cancer research.
[49] R. Kessler,et al. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. , 1998, JAMA.
[50] A. Pfeifer,et al. Mechanisms of action of indole-3-carbinol as a chemopreventive agent. , 1998, Biochemical Society transactions.
[51] L. Mofenson. Perinatal transmission of HIV in women receiving zidovudine: abstract and commentary. , 1998, JAMA.
[52] G. Williamson,et al. Characterization of flavonoids as monofunctional or bifunctional inducers of quinone reductase in murine hepatoma cell lines. , 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[53] H. Ciolino,et al. Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells. , 1998, Biochemical pharmacology.
[54] P. Hrelia,et al. The pitfall of detoxifying enzymes. , 1998, Mutation research.
[55] J. Arbiser,et al. Curcumin Is an In Vivo Inhibitor of Angiogenesis , 1998, Molecular medicine.
[56] M. Wallig,et al. Induction of rat pancreatic glutathione S-transferase and quinone reductase activities by a mixture of glucosinolate breakdown derivatives found in Brussels sprouts. , 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[57] S. Srivastava,et al. Differential induction of NAD(P)H:quinone oxidoreductase by anti-carcinogenic organosulfides from garlic. , 1998, Biochemical and biophysical research communications.
[58] T C Chou,et al. Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells. , 1998, Carcinogenesis.
[59] E. Jeffery,et al. A comparison of the individual and collective effects of four glucosinolate breakdown products from brussels sprouts on induction of detoxification enzymes. , 1998, Toxicology and applied pharmacology.
[60] M. Suschetet,et al. Modification of hepatic drug-metabolizing enzymes in rats treated with alkyl sulfides. , 1997, Cancer letters.
[61] G. Williamson,et al. Induction of the anticarcinogenic marker enzyme, quinone reductase, in murine hepatoma cells in vitro by flavonoids. , 1997, Cancer letters.
[62] Y. Fujii‐Kuriyama,et al. Ah receptor, a novel ligand-activated transcription factor. , 1997, Journal of biochemistry.
[63] Y. Lou,et al. Some Perspectives on Dietary Inhibition of Carcinogenesis: Studies with Curcumin and Tea , 1997, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[64] J. Pezzuto,et al. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos) , 1997 .
[65] J. Pezzuto,et al. Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase. , 1997, Journal of natural products.
[66] G. Williamson,et al. Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism. , 1997, Carcinogenesis.
[67] J. Pezzuto,et al. Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid. , 1997, Cancer research.
[68] J. Pezzuto,et al. Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent. , 1997, Cancer research.
[69] T. Kensler. Chemoprevention by inducers of carcinogen detoxication enzymes. , 1997, Environmental health perspectives.
[70] H. Sies,et al. Oxidative stress: oxidants and antioxidants , 1997, Experimental physiology.
[71] J. Pezzuto,et al. Assessment of cyclooxygenase inhibitors using in vitro assay systems , 1997 .
[72] R A Goldbohm,et al. A review of mechanisms underlying anticarcinogenicity by brassica vegetables. , 1997, Chemico-biological interactions.
[73] J. Pezzuto,et al. Plant-derived anticancer agents. , 1997, Biochemical pharmacology.
[74] J. Potter,et al. Vegetables, fruit, and cancer prevention: a review. , 1996, Journal of the American Dietetic Association.
[75] P. Talalay,et al. Chemoprotection against cancer by isothiocyanates and glucosinolates. , 1996, Biochemical Society transactions.
[76] T. Konoshima,et al. Anti-tumor-promoting activities of triterpenoids from ferns. I. , 1996, Biological & pharmaceutical bulletin.
[77] M. Sporn. The war on cancer , 1996, The Lancet.
[78] H. Mukhtar,et al. Tea in chemoprevention of cancer. , 1996, International journal of oncology.
[79] J. Fahey,et al. Chemoprotection against cancer by phase 2 enzyme induction. , 1995, Toxicology letters.
[80] L. Amzel,et al. The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[81] L. McKee,et al. Selected nutritional and quality analyses of tomatillos (Physalis ixocarpa) , 1995, Plant foods for human nutrition.
[82] D Kromhout,et al. Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study. , 1995, Archives of internal medicine.
[83] J. Pezzuto,et al. Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. , 1995, Carcinogenesis.
[84] Y. Lou,et al. Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice. , 1994, Cancer research.
[85] J. Pezzuto,et al. Structure-activity relationships of brassinin in preventing the development of carcinogen-induced mammary lesions in organ culture. , 1994, Anticancer research.
[86] T. Kensler,et al. Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[87] G. Stoner,et al. Cancer chemoprevention: principles and prospects. , 1993, Carcinogenesis.
[88] G. Kelloff,et al. Chemoprevention of colon carcinogenesis by organosulfur compounds. , 1993, Cancer research.
[89] A. Kinghorn,et al. Human Medicinal Agents from Plants , 1993 .
[90] F. Cano,et al. Plants used in Guatemala for the treatment of gastrointestinal disorders. IV. Vibriocidal activity of five American plants used to treat infections. , 1993, Journal of ethnopharmacology.
[91] V. Annapurna,et al. Effect of turmeric and curcumin on BP-DNA adducts. , 1993, Carcinogenesis.
[92] V. Steele,et al. Screening for chemopreventive (anticarcinogenic) compounds in rodents. , 1992, Mutation research.
[93] H. Chiang,et al. Antitumor agent, physalin F from Physalis angulata L. , 1992, Anticancer research.
[94] S. Bhide,et al. Curcumin as an inhibitor of cancer. , 1992, Journal of the American College of Nutrition.
[95] A. Santamaria,et al. Rapid detection of inducers of enzymes that protect against carcinogens. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[96] C. Cho,et al. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[97] J. Potter,et al. Vegetables, fruit, and cancer. II. Mechanisms , 1991, Cancer Causes & Control.
[98] J. Potter,et al. Vegetables, fruit, and cancer. I. Epidemiology , 1991, Cancer Causes & Control.
[99] R. Mehta,et al. Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol. , 1991, Anticancer research.
[100] H. Ammon,et al. Pharmacology of Curcuma longa , 1991, Planta medica.
[101] A. Conney,et al. Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. , 1991, Cancer research.
[102] Elizabeth Kunchandy,et al. Oxygen radical scavenging activity of curcumin , 1990 .
[103] P. Talalay,et al. Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[104] M. A. Tanner,et al. Inhibition of 7,12-dimethylbenz(a)anthracene- and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin. , 1988, Cancer research.
[105] P. Talalay,et al. Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver. , 1988, Cancer research.
[106] A. Santamaria,et al. Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: a screening assay for anticarcinogenic enzyme inducers. , 1988, Analytical biochemistry.
[107] M. L. Quinn,et al. NAPRALERT: computer handling of natural product research data , 1985, J. Chem. Inf. Comput. Sci..
[108] S. M. Walters,et al. The European garden flora. Volume II. Monocotyledons (Part II). , 1985 .
[109] J. Cullen,et al. THE EUROPEAN GARDEN FLORA , 1984 .
[110] E. W. Davis,et al. The ethnomedicine of the Waorani of Amazonian Ecuador. , 1983, Journal of ethnopharmacology.
[111] K. Ascher,et al. Insect antifeedant properties of withanolides and related steroids from Solanaceae , 1980, Experientia.
[112] BEDSIDE DIAGNOSIS , 1953, The Ulster Medical Journal.
[113] J. Pezzuto,et al. Botanicals in Cancer Chemoprevention , 2004, Cancer and Metastasis Reviews.
[114] J. F. Stevens,et al. Cancer chemopreventive in vitro activities of isoflavones isolated from Iris germanica. , 2003, Planta medica.
[115] Y. Shukla,et al. Antigenotoxic potential of certain dietary constituents. , 2003, Teratogenesis, carcinogenesis, and mutagenesis.
[116] Ahmedin Jemal,et al. Cancer Statistics, 2002 , 2002, CA: a cancer journal for clinicians.
[117] J. Fahey,et al. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. , 2001, Phytochemistry.
[118] H. Shertzer,et al. The Micronutrient Indole-3-Carbinol: Implications for Disease and Chemoprevention , 2000, Drug metabolism and drug interactions.
[119] P. Talalay. Chemoprotection against cancer by induction of phase 2 enzymes. , 2000, BioFactors.
[120] D. Guyonnet,et al. Modulation of phase II enzymes by organosulfur compounds from allium vegetables in rat tissues. , 1999, Toxicology and applied pharmacology.
[121] V. Steele,et al. Modulation of in vitro biomarkers of the carcinogenic process by chemopreventive agents. , 1999, Anticancer research.
[122] Robert H. Lurie,et al. Chemoprevention of Cancer , 1999, Recent Results in Cancer Research.
[123] R. Munday,et al. Low doses of diallyl disulfide, a compound derived from garlic, increase tissue activities of quinone reductase and glutathione transferase in the gastrointestinal tract of the rat. , 1999, Nutrition and cancer.
[124] M. Virgen,et al. Antimicrobial Activity of Medicinal Plants from Baja California Sur (México) , 1998 .
[125] P. Fernandes,et al. Technological advances in high-throughput screening. , 1998, Current opinion in chemical biology.
[126] A. Begleiter,et al. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy. , 1997, Oncology research.
[127] G. Omenn,et al. Strategy and planning for chemopreventive drug development: Clinical development plans II , 1996, Journal of cellular biochemistry. Supplement.
[128] S. Hecht,et al. Chemoprevention by isothiocyanates , 1995, Journal of cellular biochemistry. Supplement.
[129] K. L. Khanduja,et al. Impact of Quercetin Consumption on Phase-I and Phase-II Drug-Metabolizing Enzymes in Mice , 1993 .
[130] B. H. Patterson,et al. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. , 1992, Nutrition and cancer.
[131] E. Glotter. Withanolides and related ergostane-type steroids. , 1991, Natural product reports.
[132] P. Talalay. Mechanisms of induction of enzymes that protect against chemical carcinogenesis. , 1989, Advances in enzyme regulation.
[133] R. North. Down-regulation of the antitumor immune response. , 1985, Advances in cancer research.
[134] L. Wattenberg. Chemoprevention of cancer. , 1985, Cancer research.
[135] J. Johnston. Studies in natural product chemistry , 1969 .