Neurochemical and Psychopharmacological Assessment of the M1-Selective Agonist AF102B (FKS-508)

[1]  G. Kawanishi,et al.  Central muscarinic activities of an M1-selective agonist: preferential effect on reversal of amnesia , 1990, Brain Research.

[2]  Toshifumi Yamamoto,et al.  Differential effects of M1- and M2-muscarinic drugs on striatal dopamine release and metabolism in freely moving rats , 1989, Brain Research.

[3]  A. Fisher,et al.  (±)-cis-2-Methyl-spiro(1,3-oxathiolane-5,3′) quinuclidine (AF102B): A new M1 agonist attenuates cognitive dysfunctions in AF64A-treated rats , 1989, Neuroscience Letters.

[4]  Y. Iga,et al.  Beneficial effects of FKS-508 (AF102B), a selective M1 agonist, on the impaired working memory in AF64A-treated rats. , 1989, Japanese journal of pharmacology.

[5]  G. Kawanishi,et al.  Heterogeneity of muscarinic autoreceptors and heteroreceptors in the rat brain: effects of a novel M1 agonist, AF102B. , 1988, European journal of pharmacology.

[6]  A. Fisher,et al.  Dual synaptic effects of activating M1-muscarinic receptors, in superior cervical ganglia of rabbits , 1988, Brain Research.

[7]  Gwenn S. Smith.  Animal models of Alzheimer's disease: experimental cholinergic denervation , 1988, Brain Research Reviews.

[8]  D. Middlemiss.  Receptor-mediated control of neurotransmitter release from brain slices or synaptosomes. , 1988, Trends in pharmacological sciences.

[9]  Y. Iga,et al.  Amelioration of experimental amnesia (passive avoidance failure) in rodents by the selective M1 agonist AF102B. , 1988, Japanese journal of pharmacology.

[10]  Y. Iga,et al.  Effects of intracerebroventricular injection of AF64A on learning behaviors in rats. , 1988, Japanese journal of pharmacology.

[11]  K. Davis,et al.  RS 86 in the treatment of alzheimer's disease: Cognitive and biological effects , 1987, Biological Psychiatry.

[12]  K. Davis,et al.  Cholinergic approaches to the treatment of Alzheimer's disease. , 1986, British medical bulletin.

[13]  E. Perry.  The cholinergic hypothesis--ten years on. , 1986, British medical bulletin.

[14]  T. Haga,et al.  Purification of the muscarinic acetylcholine receptor from porcine brain. , 1985, The Journal of biological chemistry.

[15]  D. Mash,et al.  Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation. , 1985, Science.

[16]  M. Raiteri,et al.  Heterogeneity of presynaptic muscarinic receptors regulating neurotransmitter release in the rat brain. , 1984, The Journal of pharmacology and experimental therapeutics.

[17]  T. Haga,et al.  Affinity chromatography of the muscarinic acetylcholine receptor. , 1983, The Journal of biological chemistry.

[18]  R. Bartus,et al.  The cholinergic hypothesis of geriatric memory dysfunction. , 1982, Science.