A field programmable gate array-based biomedical noise reduction framework using advanced trilateral filter

Filtering is one of the essential tools utilized to remove undesirable features in biomedical images. Most biomedical image denoising systems are used for clinical diagnosis. So, in this paper, we use the advanced trilateral filter in the field programmable gate array (FPGA) for removing noise in the biomedical image. Generally, the trilateral filter is used as an edge preserving smoothing filter. This advanced approach of trilateral filter gives the best noise diminution and enhances the image quality. This paper also proposes the hardware implementation of an efficient FPGA-based advanced trilateral filter on real time execution. In this manuscript, we intend to design and implement the FPGA architecture using an advanced trilateral filter. Biomedical images with different noises are used during implementation and compared with the existing bilateral and trilateral architecture to assess the proposed architecture performance. For evaluating the performance metrics of the proposed advanced trilateral filter on MATLAB platform, peak signal-to-noise ratio (PSNR), mean squared error (MSE) and structured similarity index (SSIM) are calculated for different biomedical images – such as brain (MRI), chest (x-ray) and lungs (CT) – with different noises – such as salt and pepper, Gaussian, Poisson and Speckle noises – compared with existing bilateral filter and trilateral filter, respectively. The proposed advanced trilateral filter implementations are checked on Virtex-6, Virtex-7 and Zynq FPGA development board using Verilog programming language in Xilinx ISE 14.5 design tools. The simulation outcomes display that the FPGA execution of the advanced trilateral filter contains better noise removal efficiency in biomedical images compared with the existing bilateral and trilateral filter.