Prenatal Diagnosis of Down's Syndrome

A method was developed for judging the quality of womens' decision making in the field of prenatal diagnosis by measuring the internal consistency of their replies to a series of hypothetical decisions. Seventy-three nonpregnant women were interviewed using a lottery technique to elicit the risks of the birth of a Down's child at which they would request the two main procedures for prenatal diagnosis, amniocentesis and chorionic villus biopsy (CVB). The consistency of their replies was tested by performing a third lottery to elicit at what CVB related abortion risk the subject would choose CVB in preference to aminocentesis. Almost half the subjects were inconsistent, in that their indifference level on this third lottery differed by a factor of two or more from that expected from the first two lotteries.

[1]  T. Ballani.  An assessment of hazards of amniocentesis , 1990 .

[2]  R. Lilford,et al.  Management of the selected term breech presentation: assessment of the risks of selected vaginal delivery versus cesarean section for all cases. , 1987, Obstetrics and gynecology.

[3]  S G Pauker,et al.  The amniocentesis decision: ten years of decision analytic experience. , 1987, Birth defects original article series.

[4]  Ann Tabor,et al.  RANDOMISED CONTROLLED TRIAL OF GENETIC AMNIOCENTESIS IN 4606 LOW-RISK WOMEN , 1986, The Lancet.

[5]  R. Lilford,et al.  TRANSABDOMINAL CHORIONIC VILLUS SAMPLING , 1986, The Lancet.

[6]  R. Lilford,et al.  A practical assessment of ultrasound‐guided transcervical aspiration of chorionic villi and subsequent chromosomal analysis , 1985, British journal of obstetrics and gynaecology.

[7]  J. A. Freiman,et al.  Prophylactic cesarean section at term? , 1985, The New England journal of medicine.

[8]  McNay Mb,et al.  Prenatal diagnosis. Amniocentesis. , 1984 .

[9]  N. Wald,et al.  MATERNAL SERUM ALPHA-FETOPROTEIN MEASUREMENT: A SCREENING TEST FOR DOWN SYNDROME , 1984, The Lancet.

[10]  John B. Kidd,et al.  Judgement under Uncertainty: Heuristics and Biasses , 1983 .

[11]  R. Tibshirani,et al.  The Measurement of Patients' Values in Medicine , 1982, Medical decision making : an international journal of the Society for Medical Decision Making.

[12]  M. Weinstein,et al.  Clinical Decision Analysis , 1980 .

[13]  R. L. Keeney,et al.  Decisions with Multiple Objectives: Preferences and Value Trade-Offs , 1977, IEEE Transactions on Systems, Man, and Cybernetics.

[14]  E. Hook,et al.  Down syndrome in live births by single year maternal age interval in a Swedish study: comparison with results from a New York State study. , 1978, American journal of human genetics.

[15]  Stephen G. Pauker,et al.  Prenatal Diagnosis: A Directive Approach to Genetic Counseling Using Decision Analysis 1 , 1977, The Yale journal of biology and medicine.

[16]  J. Hamerton,et al.  Prenatal diagnosis of genetic disease in Canada: report of a collaborative study. , 1976, Canadian Medical Association journal.

[17]  Lee Roy Beach,et al.  Five studies of subjective equivalence , 1974 .