Purely endoscopic repair of traumatic cerebrospinal fluid rhinorrhea from the anterior skull base: case report.

A 38-year-old woman presented with a case of post-traumatic ethmoidal cerebrospinal fluid (CSF) leak that was repaired using a purely endoscopic endonasal approach. Six weeks after a mild domestic maxillofacial trauma, she started complaining of clear, watery discharge from the left nostril and headache. Neuroimaging investigations disclosed a linear fracture of the left anterior ethmoidal roof without evidence of large bony breaches or any brain tissue damage. After conservative medical treatment with carbonic anhydrase inhibitors failed, she was referred to our hospital for surgical repair of the osteodural defect. An endoscopic endonasal transethmoidal approach was successfully performed, and an overlay technique was used to reconstruct the defect. The patient was discharged without clinical evidence of CSF rhinorrhea and no leaks were apparent at the 3-month follow-up clinical and radiological examinations. Post-traumatic CSF rhinorrhea occurs in cases of dural tears associated with small bone breaks, most frequently involving the anterior skull base. Recovery is often spontaneous following only bed rest, or with medical treatments such as inhibitors of carbonic anhydrase diuretics, steroids, or eventually stool softeners to help reduce CSF pressure. Surgical repair is required when first-line conservative treatment proves ineffective. The present case shows that the endoscopic endonasal technique for the management of CSF leaks provides a less invasive surgical route to achieve valid dural repair.

[1]  F. Esposito,et al.  Natura Abhorret a Vacuo—use of fibrin glue as a filler and sealant in neurosurgical “dead spaces”. Technical note , 2010, Acta Neurochirurgica.

[2]  E. Cetinkaya,et al.  Endonasal endoscopic repair of ethmoid roof cerebrospinal fluid fistula by suturing the dura , 2008, Acta Neurochirurgica.

[3]  P. Gardner,et al.  ENDOSCOPIC RECONSTRUCTION OF THE CRANIAL BASE USING A PEDICLED NASOSEPTAL FLAP , 2008, Neurosurgery.

[4]  P. Gardner,et al.  Endoscopic endonasal suturing of dural reconstruction grafts: a novel application of the U-Clip technology. Technical note. , 2008, Journal of neurosurgery.

[5]  Pierre Robe,et al.  Surgical management of anterior cranial base fractures with cerebrospinal fluid fistulae: a single-institution experience. , 2008, Neurosurgery.

[6]  F. Esposito,et al.  Extended endoscopic endonasal approach to the midline skull base: the evolving role of transsphenoidal surgery. , 2008, Advances and technical standards in neurosurgery.

[7]  Paolo Cappabianca,et al.  Skull base reconstruction in the extended endoscopic transsphenoidal approach for suprasellar lesions. , 2007, Journal of neurosurgery.

[8]  F. Esposito,et al.  EXTENDED ENDOSCOPIC ENDONASAL TRANSSPHENOIDAL APPROACH FOR THE REMOVALOF SUPRASELLAR TUMORS: PART 2 , 2007, Neurosurgery.

[9]  D. Locatelli,et al.  Endoscopic Endonasal Approaches for Repair of Cerebrospinal Fluid Leaks: Nine-Year Experience , 2006, Neurosurgery.

[10]  P. Gardner,et al.  Evolution of reconstructive techniques following endoscopic expanded endonasal approaches. , 2005, Neurosurgical focus.

[11]  Shiang-Fu Huang,et al.  Transnasal Endoscopic Repair of Cerebrospinal Fluid Rhinorrhea and Skull Base Defect: Ten‐Year Experience , 2004, The Laryngoscope.

[12]  R. Briggs,et al.  Endoscopic transnasal intradural repair of anterior skull base cerebrospinal fluid fistulae , 2004, Journal of Clinical Neuroscience.

[13]  M. Taneda,et al.  Subdural Patch Graft Technique for Watertight Closure of Large Dural Defects in Extended Transsphenoidal Surgery , 2004, Neurosurgery.

[14]  D. Rice,et al.  Transnasal Endoscopic Closure of Cerebrospinal Fluid Leaks , 2003, The Laryngoscope.

[15]  D. Locatelli,et al.  Extended Endoscopic Approaches to the Skull Base , 2003 .

[16]  P. Cappabianca,et al.  Extended endoscopic endonasal transsphenoidal approaches to the suprasellar region, planum sphenoidale & clivus , 2003 .

[17]  P. Jabbour,et al.  [Subcranial subfrontal approach for the treatment of extensive cerebrospinal fluid leaks]. , 2002, Neuro-Chirurgie.

[18]  G. Di Giulio,et al.  Endoscopic Repair of Cerebrospinal Fluid Rhinorrhea: Learning from Our Failures , 2001, American journal of rhinology.

[19]  C. Snyderman,et al.  Endoscopic Repair of Cerebrospinal Fluid Leaks to the Sinonasal Tract: Predictors of Success , 2000, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[20]  A. Yoskovitch,et al.  Endoscopic repair of cerebrospinal fluid rhinorrhea: is it the treatment of choice? , 1999, The Journal of otolaryngology.

[21]  R. Carrau,et al.  Endoscopic endonasal transsphenoidal surgery: experience with 50 patients. , 1996, Journal of neurosurgery.

[22]  Wigand Me,et al.  Transnasal ethmoidectomy under endoscopical control. , 1981 .

[23]  M. Wigand,et al.  Transnasal ethmoidectomy under endoscopical control. , 1981, Rhinology.

[24]  M. Samii,et al.  [Indication and treatment of frontobasal rhinoliquorrhoea from the ent-surgical and neurosurgical point of view (author's transl)]. , 1978, Laryngologie, Rhinologie, Otologie.