Analyzing MEG Data with Granger Causality: Promises and Pitfalls

In this chapter we begin by introducing the basic idea of Granger causality and discussing its applications to local field potential data. We then proceed to comment on recent results of applying Granger causality to MEG data. Recognizing that Granger causality is frequently used to examine neural activity recorded during stimulus processing, we point out the adverse effects of the inevitable trial-to-trial variability of stimulus-evoked responses on Granger cau- sality estimation. We end the chapter by discussing the future prospects of using Granger causality in basic and clinical neuroscience research.

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