Aging renders the brain vulnerable to amyloid β-protein neurotoxicity
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Bruce A. Yankner | Chuang-Kuo Wu | Alfredo Lorenzo | B. Yankner | M. Yuan | A. Lorenzo | Changiz Guela | Daniel Saroff | Menglan Yuan | C. Guela | D. Saroff | Chuang‐Kuo Wu
[1] L. Mucke,et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein , 1995, Nature.
[2] S. Younkin,et al. Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice , 1996, Science.
[3] Carl W. Cotman,et al. In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity , 1991, Brain Research.
[4] B. Yankner,et al. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[5] P. Davies,et al. A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[6] D. Kirschner,et al. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. , 1990, Science.
[7] H. Wiśniewski,et al. Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome , 1985, Annals of neurology.
[8] R. Wetzel,et al. Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide. , 1995, Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration.
[9] G. Glenner,et al. Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein , 1984 .
[10] B. Yankner. Mechanisms of Neuronal Degeneration in Alzheimer's Disease , 1996, Neuron.
[11] D. Selkoe,et al. Alzheimer's Disease--Genotypes, Phenotype, and Treatments , 1997, Science.
[12] Carl W. Cotman,et al. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[13] B. Sommer,et al. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[14] B. Yankner,et al. β-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding , 1995, Neuron.
[15] S D Rogers,et al. Fibrillar -amyloid Induces Microglial Phagocytosis, Expression of Inducible Nitric Oxide Synthase, and Loss of a Select Population of Neurons in the Rat Cns in Vivo , 2022 .
[16] K. Iqbal,et al. Alzheimer's disease : biology, diagnosis, and therapeutics , 1996 .
[17] D. Selkoe,et al. Isolation of Low‐Molecular‐Weight Proteins from Amyloid Plaque Fibers in Alzheimer's Disease , 1986, Journal of neurochemistry.
[18] D. Ferrari,et al. Activation of microglial cells by β-amyloid protein and interferon-γ , 1995, Nature.
[19] C. Masters,et al. Amyloid plaque core protein in Alzheimer disease and Down syndrome. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[20] M. Beal,et al. In vivo neurotoxicity of beta-amyloid [β(1–40)] and the β(25–35) fragment , 1992, Neurobiology of Aging.
[21] K. Murakami,et al. Formation of β-amyloid protein deposits in brains of transgenic mice , 1991, Nature.
[22] N. Bons,et al. Senile plaques and neurofibrillary changes in the brain of an aged lemurian primate, Microcebus murinus , 1992, Neurobiology of Aging.
[23] M. Mattson,et al. Calcium-destabilizing and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF , 1993, Brain Research.
[24] M. Beal,et al. An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[25] P. May,et al. β-amyloid peptide in vitro toxicity: Lot-to-lot variability , 1992, Neurobiology of Aging.
[26] G. Cole,et al. Effects of injected Alzheimer beta-amyloid cores in rat brain. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[27] A. Roher,et al. Specific Domains of β-Amyloid from Alzheimer Plaque Elicit Neuron Killing in Human Microglia , 1996, The Journal of Neuroscience.
[28] D. Price,et al. Senile plaques in cortex of aged normal monkeys , 1985, Brain Research.
[29] D. Selkoe,et al. Microinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicity. , 1993, The American journal of pathology.
[30] D. Price,et al. Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. , 1987, Science.
[31] D. Price,et al. Synaptic pathology and glial responses to neuronal injury precede the formation of senile plaques and amyloid deposits in the aging cerebral cortex. , 1994, The American journal of pathology.
[32] A. Paetau,et al. A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1 , 1998, Nature Medicine.
[33] G. Drewes,et al. Microtubule‐associated Protein Tau, Paired Helical Filaments, and Phosphorylation a , 1993, Annals of the New York Academy of Sciences.
[34] B. Hyman,et al. Aβ Deposition Is Associated with Neuropil Changes, but not with Overt Neuronal Loss in the Human Amyloid Precursor Protein V717F (PDAPP) Transgenic Mouse , 1997, The Journal of Neuroscience.
[35] Bruce A. Yankner,et al. Methodological variables in the assessment of beta amyloid neurotoxicity , 1992, Neurobiology of Aging.