Late appearance of low back pain relating to Modic change after lumbar discectomy

Background: In practice of neurosurgery, we find that a wide number of patients referred for refractory low back pain have a history of lumbar discectomy. In a large number of them, magnetic resonance imaging (MRI) studies detect Modic changes (MCs). The aim of this study is to determine the relationship between emergence of MC and low back after lumbar discectomy. Materials and Methods: Three hundred and fifty-eight patients with a medical history of discectomy had a MC at the level of the operated disc without any other discopathy. They have been selected from among the 1154 patients operated for lumbar disc herniation over 5 years. Results: Two hundred and fourteen patients (67.30%) had not presented MCs on preoperative MRI. Conclusion: Our study awakens a strong presumption about the relationship between emergence of MC after lumbar discectomy.

[1]  Aske Foldbjerg Laustsen,et al.  Do Modic changes have an impact on clinical outcome in lumbar spine surgery? A systematic literature review , 2016, European Spine Journal.

[2]  J. Niinimäki,et al.  Association between changes in lumbar Modic changes and low back symptoms over a two-year period , 2015, BMC Musculoskeletal Disorders.

[3]  T. Vehmas,et al.  Modic type I change may predict rapid progressive, deforming disc degeneration: a prospective 1-year follow-up study , 2012, European Spine Journal.

[4]  Michael T. Modic,et al.  Imaging of lumbar degenerative disk disease: history and current state , 2011, Skeletal Radiology.

[5]  J. Maarrawi,et al.  What happens to Modic changes following lumbar discectomy? Analysis of a cohort of 41 patients with a 3- to 5-year follow-up period. , 2010, Journal of neurosurgery. Spine.

[6]  N Bogduk,et al.  The pathophysiology of disc degeneration: a critical review. , 2008, The Journal of bone and joint surgery. British volume.

[7]  Yue-Hui Zhang,et al.  Modic changes: a systematic review of the literature , 2008, European Spine Journal.

[8]  R Rahme,et al.  The Modic Vertebral Endplate and Marrow Changes: Pathologic Significance and Relation to Low Back Pain and Segmental Instability of the Lumbar Spine , 2008, American Journal of Neuroradiology.

[9]  P Kjaer,et al.  Modic changes, possible causes and relation to low back pain. , 2008, Medical hypotheses.

[10]  M. Modic,et al.  Modic type 1 and type 2 changes. , 2007, Journal of neurosurgery. Spine.

[11]  J. Niinimäki,et al.  A Three-Year Follow-up of Lumbar Spine Endplate (Modic) Changes , 2006, Spine.

[12]  M. Myers,et al.  Understanding end plate changes associated with disc surgery , 2002 .

[13]  C. Pfirrmann,et al.  Magnetic Resonance Classification of Lumbar Intervertebral Disc Degeneration , 2001, Spine.

[14]  M. Zanetti,et al.  MR imaging of the lumbar spine: prevalence of intervertebral disk extrusion and sequestration, nerve root compression, end plate abnormalities, and osteoarthritis of the facet joints in asymptomatic volunteers. , 1998, Radiology.

[15]  J. P. Thompson,et al.  Magnetic resonance imaging reflects the chemical changes of aging degeneration in the human intervertebral disk. , 1991, The Journal of rheumatology. Supplement.

[16]  T J Masaryk,et al.  Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging. , 1988, Radiology.

[17]  A. Roos,et al.  MR imaging of marrow changes adjacent to end plates in degenerative lumbar disk disease. , 1987, AJR. American journal of roentgenology.

[18]  J. Peyron Biologie du disque intervertébral. , 1967 .