Prejunctional Control of pH 6‐Induced Bronchoconstriction by NK1, NK2, μ‐Opioid, α2‐Adrenoceptor and Glucocorticoid Receptors in Guinea‐pig Isolated Perfused Lung

This study investigated the release of calcitonin‐gene related peptide‐like (CGRP) immunoreactivity and bronchoconstriction induced by pH 6 buffer in guinea‐pig isolated perfused lung.

[1]  P. Barnes.  Molecular mechanisms of steroid action in asthma. , 1996, The Journal of allergy and clinical immunology.

[2]  J. Brokaw,et al.  Effect of dexamethasone treatment on the regional distribution of neutral endopeptidase activity in the rat trachea , 1995, Neuropeptides.

[3]  A. Sisto,et al.  Comparison of tachykinin NK1 and NK2 receptors in the circular muscle of the guinea‐pig ileum and proximal colon , 1994, British journal of pharmacology.

[4]  E. Wolfgang,et al.  Cardiovascular effects of CP-96,345, a non-peptide blocker of tachykinin NK1 receptors. , 1994, European journal of pharmacology.

[5]  R. Håkanson,et al.  Non‐specific actions of the non‐peptide tachykinin receptor antagonists, CP‐96, 345, RP 67580 and SR 48968, on neurotransmission , 1994, British journal of pharmacology.

[6]  P. Soubrié,et al.  In vitro and in vivo biological activities of SR140333, a novel potent non-peptide tachykinin NK1 receptor antagonist. , 1993, European journal of pharmacology.

[7]  J. Lundberg,et al.  Lactic acid-induced plasma protein extravasation in rat airways by stimulation of sensory nerves and NK1 receptor activation. , 1993, Pharmacology & toxicology.

[8]  H. Inoue,et al.  Profile of capsaicin‐induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid‐induced ear oedema , 1993, British journal of pharmacology.

[9]  L. Y. Lee,et al.  Postjunctional inhibitory effect of the NK2 receptor antagonist, SR 48968, on sensory NANC bronchoconstriction in the guinea‐pig , 1993, British journal of pharmacology.

[10]  J. Hieble,et al.  Pharmacologic and therapeutic applications of alpha 2-adrenoceptor subtypes. , 1993, Annual review of pharmacology and toxicology.

[11]  J. Lundberg,et al.  Inhibition of low pH evoked activation of airway sensory nerves by capsazepine, a novel capsaicin-receptor antagonist. , 1992, Biochemical and biophysical research communications.

[12]  A. Franco‐Cereceda,et al.  Capsazepine inhibits low pH- and lactic acid-evoked release of calcitonin gene-related peptide from sensory nerves in guinea-pig heart. , 1992, European journal of pharmacology.

[13]  A. Franco‐Cereceda,et al.  Variable alpha 2-adrenoceptor-mediated inhibition of bronchoconstriction and peptide release upon activation of pulmonary afferents. , 1992, European journal of pharmacology.

[14]  E. Naline,et al.  A potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor. , 1992, Life sciences.

[15]  C. Maggi,et al.  Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: Mechanism of action and biological response , 1991, Neuroscience.

[16]  L. Garraway,et al.  Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones. , 1991, Biochemistry.

[17]  C. Maggi,et al.  Tachykinin receptors in the guinea-pig isolated bronchi. , 1991, European journal of pharmacology.

[18]  J. Howbert,et al.  Species differences in affinities of non-peptide antagonists for substance P receptors. , 1991, European journal of pharmacology.

[19]  S. Bevan,et al.  Protons activate a cation conductance in a sub‐population of rat dorsal root ganglion neurones. , 1991, The Journal of physiology.

[20]  D. Gruenert,et al.  Glucocorticoids induce neutral endopeptidase in transformed human tracheal epithelial cells. , 1991, The American journal of physiology.

[21]  J. Lowe,et al.  A potent nonpeptide antagonist of the substance P (NK1) receptor. , 1991, Science.

[22]  S. Nakanishi,et al.  Selective inhibition of expression of the substance P receptor mRNA in pancreatic acinar AR42J cells by glucocorticoids. , 1990, The Journal of biological chemistry.

[23]  W. Hutchison,et al.  Morphine does not reduce the intraspinal release of calcitonin gene-related peptide in the cat , 1990, Neuroscience Letters.

[24]  J. Karlsson,et al.  Capsaicin-induced bronchoconstriction and neuropeptide release in guinea pig perfused lungs. , 1990, Journal of applied physiology.

[25]  A. Carayon,et al.  Opioid control of the in vitro release of calcitonin gene-related peptide from primary afferent fibres projecting in the rat cervical cord , 1989, Neuropeptides.

[26]  R. Matran,et al.  Inhibition of cholinergic and non-adrenergic, non-cholinergic bronchoconstriction in the guinea pig mediated by neuropeptide Y and alpha 2-adrenoceptors and opiate receptors. , 1989, European journal of pharmacology.

[27]  K. Chung,et al.  Opioid modulation of non‐cholinergic neural bronchoconstriction in guinea‐pig in vivo , 1988, British journal of pharmacology.

[28]  N. Rhaleb,et al.  Characterization of neurokinin receptors in various isolated organs by the use of selective agonists. , 1987, Life sciences.

[29]  P. Portoghese,et al.  Evidence for the interaction of morphine with kappa and delta opioid receptors to induce analgesia in beta-funaltrexamine-treated mice. , 1987, The Journal of pharmacology and experimental therapeutics.

[30]  A. Saria,et al.  Effects and distribution of vagal capsaicin-sensitive substance P neurons with special reference to the trachea and lungs. , 1983, Acta physiologica Scandinavica.

[31]  E. Brodin,et al.  Morphine inhibits substance P release from peripheral sensory nerve endings. , 1983, Acta physiologica Scandinavica.

[32]  P. Wood,et al.  Multiple opiate receptors: Differential binding of μ, κ and δ agonists , 1981, Neuropharmacology.