Evidence of cortical reorganization in hemiparetic patients.

We studied the mechanisms underlying the recovery of motor function of the hand using a bidimensional xenon-133 inhalation technique to measure regional cerebral blood flow at rest and during the performance of a motor task (test condition). The regional cerebral blood flow patterns under rest and test conditions were compared in normal control and in stroke patients with either a cortico-subcortical or a deep-seated lesion. Functional recovery appears to depend upon cortical reorganization involving both hemispheres, particularly in both parietal regions in the subgroup of patients with cortico-subcortical lesions.

[1]  G. Demeurisse,et al.  Lack of evolution of the cerebral blood flow during clinical recovery of a stroke. , 1983, Stroke.

[2]  W. Smith.  The Integrative Action of the Nervous System , 1907, Nature.

[3]  M. Raichle,et al.  In vivo correlation between regional cerebral blood flow and oxygen utilization in man. , 1975, Transactions of the American Neurological Association.

[4]  H. Thompson,et al.  Regional Cerebral Blood Flow Estimated by 133Xenon Inhalation , 1975 .

[5]  G. Demeurisse,et al.  The Prognostic Value of rCBF Measurements in Aphasic Stroke Patients , 1985 .

[6]  J Risberg,et al.  Cerebral Hemodynamic Response to Mental Activation in Normo‐ and Hypercapnia , 1980, Stroke.

[7]  J. Risberg,et al.  Regional Cerebral Blood Flow by 133Xenon Inhalation: Preliminary Evaluation of an Initial Slope Index in Patients with Unstable Flow Compartments , 1975, Stroke.

[8]  J. Olesen,et al.  Contralateral focal increase of cerebral blood flow in man during arm work. , 1971, Brain : a journal of neurology.

[9]  E. M. Wilson,et al.  Regional cerebral blood flow comparison of right and left hand movement , 1979, Neurology.

[10]  N. Leigh,et al.  Core Text of Neuroanatomy , 1986 .

[11]  P. Roland,et al.  Focal increase of cerebral blood flow during stereognostic testing in man. , 1976, Archives of neurology.

[12]  W. Demyer,et al.  The quantitative cortical origin of pyramidal axons of Macaca rhesus , 1961, Neurology.

[13]  E. M. Wilson,et al.  Brain activation in the presence of brain damage , 1980, Brain and Language.