Reliability of miRNA Microarray Platforms: An Approach Based on Random Effects Linear Models

MiRNAs are short ribonucleic acid (RNA) molecules, acting as post-transcriptional regulators. Intensity levels of thousand of miRNAs are commonly measured via microarray platforms,with pros and cons similar to those for gene expression arrays.

[1]  F. Slack,et al.  Oncomirs — microRNAs with a role in cancer , 2006, Nature Reviews Cancer.

[2]  Frédéric Lemoine,et al.  Concordance among digital gene expression, microarrays, and qPCR when measuring differential expression of microRNAs. , 2010, BioTechniques.

[3]  J. Ware,et al.  Random-effects models for longitudinal data. , 1982, Biometrics.

[4]  R. Zager,et al.  HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney. , 1994, Kidney international.

[5]  Christian A. Rees,et al.  Systematic variation in gene expression patterns in human cancer cell lines , 2000, Nature Genetics.

[6]  S. Aaronson,et al.  In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. , 1973, Journal of the National Cancer Institute.

[7]  R. Ach,et al.  Measuring microRNAs: Comparisons of microarray and quantitative PCR measurements, and of different total RNA prep methods , 2008, BMC biotechnology.

[8]  R. Aharonov,et al.  Identification of hundreds of conserved and nonconserved human microRNAs , 2005, Nature Genetics.

[9]  H. Horvitz,et al.  MicroRNA expression profiles classify human cancers , 2005, Nature.

[10]  Andrew Williams,et al.  Cross-platform analysis of global microRNA expression technologies , 2010, BMC Genomics.

[11]  Satterthwaite Fe.  An approximate distribution of estimates of variance components. , 1946 .

[12]  Pasko Rakic,et al.  Microarray analysis of microRNA expression in the developing mammalian brain , 2004, Genome Biology.

[13]  Eric C Lai,et al.  microRNAs: Runts of the Genome Assert Themselves , 2003, Current Biology.

[14]  D. Bates,et al.  Mixed-Effects Models in S and S-PLUS , 2001 .

[15]  Gozoh Tsujimoto,et al.  Intra-Platform Repeatability and Inter-Platform Comparability of MicroRNA Microarray Technology , 2009, PloS one.

[16]  Paula K Shireman,et al.  Reproducibility of quantitative RT-PCR array in miRNA expression profiling and comparison with microarray analysis , 2009 .

[17]  V. Ambros.  MicroRNA Pathways in Flies and Worms Growth, Death, Fat, Stress, and Timing , 2003, Cell.

[18]  J. Fogh.  Human Tumor Cells in Vitro , 1975, Springer US.