Prevalence of Wheat/Gluten-Related Disorders and Gluten-Free Diet in Paraguay: An Online Survey-Based Study

Gluten-related disorders (GRDs) are increasing around the world, but their magnitude and relevance remain unknown in most Latin American countries. Thus, an online survey was conducted to estimate the prevalence of GRDs as well as adherence to a gluten-free diet (GFD) in Paraguayan adult population. There were 1058 individuals surveyed using a validated questionnaire (response rate of 93.9%). The self-reported prevalence rates were as follows (95% CI): gluten sensitivity (GS), 10.30% (8.53–12.29); non-celiac GS (NCGS), 5.19% (3.94–6.71); physician-diagnosed celiac disease (PD-CD), 3.11% (2.15–4.35); wheat allergy (WA), 2.07% (1.30–3.13); and adherence to GFD, 15.69% (13.55–18.02). Excluding CD, more women than men met the criteria for GRDs, adverse food reactions, and GFD (p < 0.05). Eight respondents reported the coexistence of NCGS with PD-CD and/or WA. Most cases on a GFD indicated medical/dietitian advice for following the diet (68.07%). Non-self-reported GS individuals indicated weight control (46.4%) and the notion that the GFD is healthier (20.2%) as the main motivations for following the diet. GRDs are not uncommon in Paraguayan adult population. It seems that there is awareness about GRDs and the GFD, but training about the diagnosis of GRDs is desirable because of the informed overlapping diagnoses of CD or WA with NCGS. Future studies involving face-to-face interviews are necessary.

[1]  A. Oyarzún,et al.  Living with Gluten and Other Food Intolerances: Self-Reported Diagnoses and Management , 2020, Nutrients.

[2]  L. Flores-Mendoza,et al.  Prevalence of Adverse Reactions to Glutenand People Going on a Gluten-Free Diet:A Survey Study Conducted in Brazil , 2020, Medicina.

[3]  B. Cabanillas Gluten-related disorders: Celiac disease, wheat allergy, and nonceliac gluten sensitivity , 2019, Critical reviews in food science and nutrition.

[4]  D. Sanders,et al.  A Population Survey of Dietary Attitudes towards Gluten , 2019, Nutrients.

[5]  F. Cabrera-Chávez,et al.  Gluten Vehicle and Placebo for Non-Celiac Gluten Sensitivity Assessment , 2019, Medicina.

[6]  María Mercedes Carpinelli,et al.  Anticuerpo anti-transglutaminasa tisular en adultos con enfermedad celíaca y su relación con la presencia y duración de la dieta libre de gluten , 2018 .

[7]  J. Thiery,et al.  Will the Real Coeliac Disease Please Stand Up? Coeliac Disease Prevalence in the German LIFE Child Study , 2018, Journal of pediatric gastroenterology and nutrition.

[8]  A. Lopata,et al.  Prevalence of food allergy in Vietnam: comparison of web-based with traditional paper-based survey , 2018, The World Allergy Organization journal.

[9]  N. Talley,et al.  Wheat Intolerance and Chronic Gastrointestinal Symptoms in an Australian Population‐based Study: Association Between Wheat Sensitivity, Celiac Disease and Functional Gastrointestinal Disorders , 2018, The American Journal of Gastroenterology.

[10]  F. Cabrera-Chávez,et al.  Prevalence of Self-Reported Gluten-Related Disorders and Adherence to a Gluten-Free Diet in Salvadoran Adult Population , 2018, International journal of environmental research and public health.

[11]  G. Rogler,et al.  Celiac Disease is Misdiagnosed Based on Serology Only in a Substantial Proportion of Patients , 2016, Journal of clinical gastroenterology.

[12]  Ingrid Celeste Centurión Medina,et al.  Calidad de vida en adultos del Paraguay con enfermedad celiaca , 2018 .

[13]  F. Cabrera-Chávez,et al.  Prevalence of Self-Reported Gluten Sensitivity and Adherence to a Gluten-Free Diet in Argentinian Adult Population , 2017, Nutrients.

[14]  D. Sanders,et al.  Prevalence and Characterization of Self-Reported Gluten Sensitivity in The Netherlands , 2016, Nutrients.

[15]  D. Granda-Restrepo,et al.  Self-Reported Prevalence of Gluten-Related Disorders and Adherence to Gluten-Free Diet in Colombian Adult Population , 2016, Gastroenterology research and practice.

[16]  F. Cabrera-Chávez,et al.  Self-Reported Prevalence of Symptomatic Adverse Reactions to Gluten and Adherence to Gluten-Free Diet in an Adult Mexican Population , 2015, Nutrients.

[17]  D. Schuppan,et al.  Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria , 2015, Nutrients.

[18]  M. Y. Hardy,et al.  Assessing of Celiac Disease and Nonceliac Gluten Sensitivity , 2015, Gastroenterology research and practice.

[19]  L. Flores-Mendoza,et al.  Food Allergy : Prevalence and Food Technology Approaches for the Control of IgE-mediated Food Allergy , 2014 .

[20]  G. Corazza,et al.  An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity , 2014, BMC Medicine.

[21]  D. Sanders,et al.  A UK study assessing the population prevalence of self-reported gluten sensitivity and referral characteristics to secondary care , 2014, European journal of gastroenterology & hepatology.

[22]  R. Delor,et al.  La Enfermedad celiaca en el Paraguay , 2011 .