The effects of age on patient-reported outcome measures in total knee replacements.

We present a comparison of patient-reported outcomes (PROMs) in relation to patient age, in patients who had received a total (TKR) or unicompartmental knee replacement (UKR). The outcome was evaluated using the Oxford knee score (OKS), EuroQol (EQ-5D) and satisfaction scores. Patients aged 65 to 84 years demonstrated better pre-operative function scores than those aged < 65 years (OKS, p = 0.03; EQ-5D, p = 0.048) and those aged ≥ 85 years (OKS, p = 0.03). Post-operative scores were comparable across age groups, but a linear trend for greater post-operative improvement in OKS and EQ-5D was seen with decreasing age (p < 0.033). The overall mean satisfaction score at six months was 84.9, but those aged < 55 years exhibited a lower mean level of satisfaction (78.3) compared with all other age groups (all p < 0.031). The cumulative overall two-year revision rate was 1.3%. This study demonstrates that good early outcomes, as measured by the OKS and EQ-5D, can be anticipated following knee replacement regardless of the patient's age, although younger patients gain greater improvement. However, the lower satisfaction in those aged < 55 years is a concern, and suggests that outcome is not fully encapsulated by the OKS and EQ-5D evaluation, and raises the question whether the OKS alone is an appropriate measure of pain and function in younger, more active individuals.

[1]  D. Murray,et al.  Oxford medial unicompartmental knee arthroplasty in patients younger and older than 60 years of age. , 2005, The Journal of bone and joint surgery. British volume.

[2]  M. C. de Waal Malefijt,et al.  Patient satisfaction after total knee arthroplasty: a comparison between subjective and objective outcome assessments. , 2001, The Journal of arthroplasty.

[3]  M. Cross,et al.  Hydroxyapatite-coated, cementless total knee replacement in patients aged 75 years and over. , 2004, The Journal of bone and joint surgery. British volume.

[4]  T. Peters,et al.  Population requirement for primary knee replacement surgery: a cross-sectional study. , 2003, Rheumatology.

[5]  D C Voaklander,et al.  The effect of age on pain, function, and quality of life after total hip and knee arthroplasty. , 2001, Archives of internal medicine.

[6]  G. Scuderi**,et al.  Total Knee Replacement in Young, Active Patients. Long-Term Follow-up and Functional Outcome* , 1997, The Journal of bone and joint surgery. American volume.

[7]  Replacements , 2000, Practice and Procedure of the International Criminal Tribunal for the Former Yugoslavia.

[8]  M. Ritter,et al.  Total joint arthroplasty in the extremely elderly: hip and knee arthroplasty after entering the 89th year of life. , 2003, The Journal of arthroplasty.

[9]  John E. Brazier,et al.  Comparison of the minimally important difference for two health state utility measures: EQ-5D and SF-6D , 2005, Quality of Life Research.

[10]  Robert S. Dittus,et al.  Health-Related Quality of Life after Knee Replacement: Results of the Knee Replacement Patient Outcomes Research Team Study* , 1998 .

[11]  C. Tai,et al.  Five- to 12-year follow-up of a hydroxyapatite-coated, cementless total knee replacement in young, active patients. , 2006, The Journal of bone and joint surgery. British volume.

[12]  Adam C. Brekke,et al.  Development of a New Knee Society Scoring System , 2012, Clinical orthopaedics and related research.

[13]  Karon F Cook,et al.  The John Insall Award: Patient Expectations Affect Satisfaction with Total Knee Arthroplasty , 2006, Clinical orthopaedics and related research.

[14]  S. Talbot,et al.  Use of a new high-activity arthroplasty score to assess function of young patients with total hip or knee arthroplasty. , 2010, The Journal of arthroplasty.

[15]  S. Toksvig-Larsen,et al.  Knee arthroplasty: are patients' expectations fulfilled? , 2009, Acta orthopaedica.

[16]  A. Carr,et al.  Are pain and function better measures of outcome than revision rates after TKR in the younger patient? , 2010, The Knee.

[17]  R Flanigan,et al.  What should we do? , 1999, Bioethics forum.

[18]  A. Carr,et al.  Questionnaire on the perceptions of patients about total knee replacement. , 1998, The Journal of bone and joint surgery. British volume.

[19]  Rd Dripps,et al.  New classification of physical status , 1963 .

[20]  B. Morrey Assessing patients for joint replacement: can pre-operative Oxford hip and knee scores be used to predict patient satisfaction following joint replacement surgery and to guide patient selection? , 2012 .

[21]  M. Bonnin,et al.  Can patients really do sport after TKA? , 2010, Knee Surgery, Sports Traumatology, Arthroscopy.

[22]  N. Caplan,et al.  Rating Systems in the Evaluation of Knee Ligament Injuries , 2014 .

[23]  J. Lonner,et al.  Total knee arthroplasty in patients 90 years of age and older. , 1999, The Journal of arthroplasty.

[24]  J. Ware,et al.  A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. , 1996, Medical care.

[25]  L. Kennedy,et al.  When should we do knee replacements? , 2003, The Knee.

[26]  James G Wright,et al.  Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review. , 2008, Canadian journal of surgery. Journal canadien de chirurgie.

[27]  P. D. Di Cesare,et al.  Total hip and knee arthroplasty in nonagenarians. , 2007, The Journal of arthroplasty.

[28]  C. Bombardier,et al.  Variation in orthopedic surgeons' perceptions of the indications for and outcomes of knee replacement. , 1995, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[29]  A. Williams EuroQol : a new facility for the measurement of health-related quality of life , 1990 .

[30]  N. Bellamy,et al.  Validation study of WOMAC : a health status instrument for measuring clinically-important patient-relevant outcomes following total hip or knee arthroplasty in osteoarthritis , 1988 .

[31]  J. Ranstam,et al.  The Swedish Knee Arthroplasty Register , 2014, Bone & joint research.

[32]  K. C. Chan,et al.  5- to 18-year follow-up study of cemented total knee arthroplasty for patients 55 years old or younger. , 1997, The Journal of arthroplasty.

[33]  J. Lewsey,et al.  The role of pain and function in determining patient satisfaction after total knee replacement. Data from the National Joint Registry for England and Wales. , 2007, The Journal of bone and joint surgery. British volume.

[34]  J. M. Quintana,et al.  Effect of patient characteristics on reported outcomes after total knee replacement. , 2007, Rheumatology.

[35]  Daniel J Berry,et al.  Cemented total knee arthroplasty using a modern prosthesis in young patients with osteoarthritis. , 2007, The Journal of arthroplasty.

[36]  R. Bourne,et al.  Influence of Patient Factors on TKA Outcomes at 5 to 11 Years Followup , 2007, Clinical orthopaedics and related research.

[37]  C. Howie,et al.  Predicting dissatisfaction following total knee replacement: a prospective study of 1217 patients. , 2010, The Journal of bone and joint surgery. British volume.

[38]  S. Toksvig-Larsen,et al.  Knee injury and Osteoarthritis Outcome Score (KOOS) – validation and comparison to the WOMAC in total knee replacement , 2003, Health and quality of life outcomes.

[39]  S. Mears,et al.  Primary total knee arthroplasty in the elderly , 2008 .

[40]  C. Ranawat,et al.  Indications for total hip and total knee arthroplasties. Results of orthopaedic surveys. , 1996, The Journal of arthroplasty.

[41]  P. Ewings,et al.  Knee scores in a 'normal' elderly population. , 2004, The Knee.

[42]  W. Harris,et al.  Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. , 1969, The Journal of bone and joint surgery. American volume.

[43]  C. Bombardier,et al.  Health-related quality of life after knee replacement. , 1998, The Journal of bone and joint surgery. American volume.

[44]  D W Murray,et al.  The use of the Oxford hip and knee scores. , 2007, The Journal of bone and joint surgery. British volume.

[45]  C. Sherbourne,et al.  The MOS 36-Item Short-Form Health Survey (SF-36) , 1992 .