The physiological significance of bronchiectasis.
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The enlargement of the bronchi is not the significant aspect of the disease called bronchiectasis. Of greater importance is the loss of the cleansing mechanism of the bronchi, leading to the retention of infection, mucus and foreign matter. Retention causes progression of the disease, toxic absorption, recurring pneumonitis and many other complications. Treatment is directed especially towards providing drainage constantly , supplemented by chemotherapy and all supportive measures which will increase the resistance of the patient. Where resection of all involved lobes or segments of lung is feasible, it offers permanent cure of the disease.
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[2] D. Corrigan. On Cirrhosis of the lung , 1838 .