An NIMH Workshop on Non-Affective Psychosis in Midlife and Beyond: Research Agenda on Phenomenology, Clinical Trajectories, Underlying Mechanisms, and Intervention Targets.

[1]  A. Tanskanen,et al.  Women with Schizophrenia-Spectrum Disorders After Menopause: A Vulnerable Group for Relapse , 2022, Schizophrenia bulletin.

[2]  G. Heninger,et al.  Abnormal levels of mitochondrial Ca2+ channel proteins in plasma neuron‐derived extracellular vesicles of early schizophrenia , 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[3]  R. Kotov,et al.  The Course of General Cognitive Ability in Individuals With Psychotic Disorders. , 2022, JAMA psychiatry.

[4]  Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 , 2022, The lancet. Psychiatry.

[5]  D. Jeste,et al.  Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia , 2021, Molecular Psychiatry.

[6]  M. Murray,et al.  Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia , 2021, Molecular Psychiatry.

[7]  R. Kotov,et al.  Two Hypotheses on the High Incidence of Dementia in Psychotic Disorders. , 2021, JAMA psychiatry.

[8]  A. Tanskanen,et al.  Antipsychotic use and risk of breast cancer in women with schizophrenia: a nationwide nested case-control study in Finland. , 2021, The lancet. Psychiatry.

[9]  M. Rettenbacher,et al.  Sex differences in antipsychotic efficacy and side effects in schizophrenia spectrum disorder: results from the BeSt InTro study , 2021, npj Schizophrenia.

[10]  T. Wykes,et al.  Effectiveness, Core Elements, and Moderators of Response of Cognitive Remediation for Schizophrenia , 2021, JAMA psychiatry.

[11]  T. Goldberg,et al.  Age-Specific Prevalence and Incidence of Dementia Diagnoses Among Older US Adults With Schizophrenia. , 2021, JAMA psychiatry.

[12]  S. Bhattacharyya,et al.  Safety and tolerability of natural and synthetic cannabinoids in adults aged over 50 years: A systematic review and meta-analysis , 2021, PLoS medicine.

[13]  D. Pizzagalli,et al.  Bioenergetics and Abnormal Functional Connectivity in Psychotic Disorders , 2020, Molecular Psychiatry.

[14]  R. Kahn,et al.  Brain age prediction in schizophrenia: Does the choice of machine learning algorithm matter? , 2020, Psychiatry Research: Neuroimaging.

[15]  James A. Evans,et al.  Slowed canonical progress in large fields of science , 2018, Proceedings of the National Academy of Sciences.

[16]  Corinne E. Fischer,et al.  Effects of repetitive paired associative stimulation on brain plasticity and working memory in Alzheimer’s disease: a pilot randomized double-blind-controlled trial , 2020, International Psychogeriatrics.

[17]  N. Swerdlow,et al.  Memantine effects on auditory discrimination and training in schizophrenia patients , 2020, Neuropsychopharmacology.

[18]  R. Murray,et al.  A single dose of cannabidiol modulates medial temporal and striatal function during fear processing in people at clinical high risk for psychosis , 2020, Translational Psychiatry.

[19]  R. Stickgold,et al.  The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized clinical trial , 2020, Neuropsychopharmacology.

[20]  J. Lieberman,et al.  Association Between the Duration of Untreated Psychosis and Selective Cognitive Performance in Community-Dwelling Individuals With Chronic Untreated Schizophrenia in Rural China. , 2020, JAMA psychiatry.

[21]  J. Glausier,et al.  Diagnosis- and Cell Type-Specific Mitochondrial Functional Pathway Signatures in Schizophrenia and Bipolar Disorder , 2020, Biological Psychiatry.

[22]  A. Tanskanen,et al.  The clinical course of schizophrenia in women and men—a nation-wide cohort study , 2020, npj Schizophrenia.

[23]  C. Cohen,et al.  Advances in the Conceptualization and Study of Schizophrenia in Later Life: 2020 Update. , 2020, Clinics in geriatric medicine.

[24]  C. Cohen,et al.  Recovery and Recovering in Older Adults with Schizophrenia: A 5-Tier Model. , 2020, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[25]  Marian E. Berryhill,et al.  Frontoparietal theta-gamma interactions track working memory enhancement with training and tDCS , 2020, NeuroImage.

[26]  D. Manoach,et al.  Targeting sleep oscillations to improve memory in schizophrenia , 2020, Schizophrenia Research.

[27]  Jun Lyu,et al.  Trends in the incidence and DALYs of schizophrenia at the global, regional and national levels: results from the Global Burden of Disease Study 2017 , 2020, Epidemiology and Psychiatric Sciences.

[28]  L. Davachi,et al.  Anterior Hippocampal-Cortical Functional Connectivity Distinguishes Antipsychotic Naïve First-Episode Psychosis Patients From Controls and May Predict Response to Second-Generation Antipsychotic Treatment. , 2019, Schizophrenia bulletin.

[29]  M. Rietschel,et al.  Insulin-signaling abnormalities in drug-naïve first-episode schizophrenia: Transduction protein analyses in extracellular vesicles of putative neuronal origin , 2019, European Psychiatry.

[30]  Christian Gaser,et al.  Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained? , 2019, Front. Neurol..

[31]  S. A. Wijtenburg,et al.  Brain insulin resistance and altered brain glucose are related to memory impairments in schizophrenia , 2019, Schizophrenia Research.

[32]  A. García-Avello,et al.  Systematic Review of Gender Bias in the Clinical Trials of New Long-Acting Antipsychotic Drugs , 2019, Journal of clinical psychopharmacology.

[33]  R. Reinhart,et al.  Working memory revived in older adults by synchronizing rhythmic brain circuits , 2019, Nature Neuroscience.

[34]  J. Gold,et al.  Cross-cultural Validation of the 5-Factor Structure of Negative Symptoms in Schizophrenia , 2019, Schizophrenia bulletin.

[35]  Anissa Abi-Dargham,et al.  Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain , 2019, Proceedings of the National Academy of Sciences.

[36]  Philip D. Harvey,et al.  Guanfacine Augmentation of a Combined Intervention of Computerized Cognitive Remediation Therapy and Social Skills Training for Schizotypal Personality Disorder. , 2019, The American journal of psychiatry.

[37]  Dennis Liu,et al.  Cognition in schizophrenia improves with treatment of severe obstructive sleep apnoea: A pilot study , 2018, Schizophrenia Research: Cognition.

[38]  J. Lindenmayer,et al.  Does social cognition training augment response to computer-assisted cognitive remediation for schizophrenia? , 2018, Schizophrenia Research.

[39]  Adrian Preda,et al.  Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium , 2018, Biological Psychiatry.

[40]  S. Heckers,et al.  Regionally specific volume deficits along the hippocampal long axis in early and chronic psychosis , 2018, NeuroImage: Clinical.

[41]  S. Reeves,et al.  Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): a randomised, controlled, double-blind trial , 2018, The lancet. Psychiatry.

[42]  P. Kurdyak,et al.  Disparities in Access to Early Psychosis Intervention Services: Comparison of Service Users and Nonusers in Health Administrative Data , 2018, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[43]  D. Jeste,et al.  Systemic Biomarkers of Accelerated Aging in Schizophrenia: A Critical Review and Future Directions , 2018, Schizophrenia bulletin.

[44]  I. Sommer,et al.  The effect of raloxifene augmentation in men and women with a schizophrenia spectrum disorder: a systematic review and meta-analysis , 2018, npj Schizophrenia.

[45]  Jie Shi,et al.  Sleep disturbances increase the risk of dementia: A systematic review and meta-analysis. , 2017, Sleep medicine reviews.

[46]  Lesley A Ross,et al.  Speed of processing training results in lower risk of dementia , 2017, Alzheimer's & dementia.

[47]  M. Barr,et al.  Impaired theta-gamma coupling during working memory performance in schizophrenia , 2017, Schizophrenia Research.

[48]  D. Jeste,et al.  Inflammation in Schizophrenia: Cytokine Levels and Their Relationships to Demographic and Clinical Variables. , 2017, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[49]  S. A. Wijtenburg,et al.  Elevated brain lactate in schizophrenia: a 7 T magnetic resonance spectroscopy study , 2016, Translational Psychiatry.

[50]  Michael F. Green,et al.  Longitudinal stability of social cognition in schizophrenia: A 5-year follow-up of social perception and emotion processing , 2016, Schizophrenia Research.

[51]  C. Arango,et al.  Progressive brain changes in children and adolescents with early-onset psychosis: A meta-analysis of longitudinal MRI studies , 2016, Schizophrenia Research.

[52]  Rebecca M. C. Spencer,et al.  Age-related Changes in the Sleep-dependent Reorganization of Declarative Memories , 2016, Journal of Cognitive Neuroscience.

[53]  C. V. van Bennekom,et al.  Effects of Continuous Positive Airway Pressure on Cognitive and Functional Outcome of Stroke Patients with Obstructive Sleep Apnea: A Randomized Controlled Trial. , 2016, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[54]  Wiepke Cahn,et al.  Accelerated Brain Aging in Schizophrenia: A Longitudinal Pattern Recognition Study. , 2016, The American journal of psychiatry.

[55]  M. Fromer,et al.  Developmental Trajectories of Impaired Community Functioning in Schizophrenia. , 2016, JAMA psychiatry.

[56]  D. Vancampfort,et al.  Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta‐analysis , 2015, World psychiatry : official journal of the World Psychiatric Association.

[57]  A. Arnsten,et al.  Dopamine’s Actions in Primate Prefrontal Cortex: Challenges for Treating Cognitive Disorders , 2015, Pharmacological Reviews.

[58]  T. Scheewe,et al.  Physical Exercise Keeps the Brain Connected: Biking Increases White Matter Integrity in Patients With Schizophrenia and Healthy Controls. , 2015, Schizophrenia bulletin.

[59]  R. Petersen,et al.  Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study , 2015, Alzheimer's & Dementia.

[60]  R. Petersen,et al.  Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural‐derived blood exosomes of preclinical Alzheimer's disease , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[61]  E. Rolls Limbic systems for emotion and for memory, but no single limbic system , 2015, Cortex.

[62]  George W Rebok,et al.  Ten‐Year Effects of the Advanced Cognitive Training for Independent and Vital Elderly Cognitive Training Trial on Cognition and Everyday Functioning in Older Adults , 2014, Journal of the American Geriatrics Society.

[63]  B. Cohen,et al.  In vivo evidence for cerebral bioenergetic abnormalities in schizophrenia measured using 31P magnetization transfer spectroscopy. , 2014, JAMA psychiatry.

[64]  D. Penn,et al.  Deficits in domains of social cognition in schizophrenia: a meta-analysis of the empirical evidence. , 2013, Schizophrenia bulletin.

[65]  R. Kahn,et al.  Brain volumes in schizophrenia: a meta-analysis in over 18 000 subjects. , 2013, Schizophrenia bulletin.

[66]  Yinming Sun,et al.  PAS-Induced Potentiation of Cortical-Evoked Activity in the Dorsolateral Prefrontal Cortex , 2013, Neuropsychopharmacology.

[67]  C. Cohen,et al.  Prevalence of negative symptoms and associated factors in older adults with schizophrenia spectrum disorder. , 2012, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[68]  R. Narendran,et al.  Increased prefrontal cortical D1 receptors in drug naïve patients with schizophrenia: a PET study with [11C]NNC112 , 2012, Journal of psychopharmacology.

[69]  M. Hellmich,et al.  Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia , 2012, Translational Psychiatry.

[70]  Ann K. Shinn,et al.  Reduced Sleep Spindles and Spindle Coherence in Schizophrenia: Mechanisms of Impaired Memory Consolidation? , 2012, Biological Psychiatry.

[71]  A. Beekman,et al.  Schizophrenia spectrum disorders in later life: prevalence and distribution of age at onset and sex in a dutch catchment area. , 2012, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[72]  C. Zeebregts,et al.  Does Extracranial Arterial Pathology Play a Role in Late-onset Psychiatric Disorders? , 2010, Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology.

[73]  R. Murray,et al.  Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology , 2010, Neuropsychopharmacology.

[74]  D. Jeste,et al.  Older schizophrenia patients have more disrupted sleep and circadian rhythms than age-matched comparison subjects. , 2005, Journal of psychiatric research.

[75]  Pierre J. Magistretti,et al.  Let There Be (NADH) Light , 2004, Science.

[76]  G. Alexopoulos,et al.  Using antipsychotic agents in older patients. , 2004, The Journal of clinical psychiatry.

[77]  R. V. Van Heertum,et al.  Prefrontal Dopamine D1 Receptors and Working Memory in Schizophrenia , 2002, The Journal of Neuroscience.

[78]  R. V. Van Heertum,et al.  Increased baseline occupancy of D2 receptors by dopamine in schizophrenia. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[79]  Philip D. Harvey,et al.  The longitudinal relationship of clinical symptoms, cognitive functioning, and adaptive life in geriatric schizophrenia , 2000, Schizophrenia Research.

[80]  B. Turetsky,et al.  Reduced gray matter volume in schizophrenia. , 1999, Archives of general psychiatry.

[81]  D. Jeste,et al.  Sleep-disordered breathing and periodic limb movements in sleep in older patients with schizophrenia , 1999, Biological Psychiatry.

[82]  R. Murray,et al.  SCHIZOPHRENIA WITH ONSET AT THE EXTREMES OF ADULT LIFE , 1997 .

[83]  P. Goldman-Rakic,et al.  Down-regulation of the D1 and D5 dopamine receptors in the primate prefrontal cortex by chronic treatment with antipsychotic drugs. , 1997, The Journal of pharmacology and experimental therapeutics.

[84]  George T. Baker,et al.  Biomarkers of aging , 1988, Experimental Gerontology.

[85]  F. Oyebode,et al.  Unilateral Auditory Hallucinations , 1988, British Journal of Psychiatry.

[86]  P. Zimbardo,et al.  Induced hearing deficit generates experimental paranoia , 1981 .