Synthesis and antimitotic activity of novel 5-aminoisoxazoles bearing alkoxyaryl moieties

[1]  A. Majouga,et al.  Synthesis and biological testing of (5Z)-2-aryl-5-arylmethylidene-3,5-dihydro-4H-imidazol-4-ones as antimitotic agents , 2016, Medicinal Chemistry Research.

[2]  N. S. Zefirov,et al.  Synthesis and biological evaluation of novel 5-hydroxylaminoisoxazole derivatives as lipoxygenase inhibitors and metabolism enhancing agents. , 2016, Bioorganic & medicinal chemistry.

[3]  V. A. Tartakovsky,et al.  Novel approaches to pharmacology-oriented and energy rich organic nitrogen–oxygen systems , 2015 .

[4]  Y. Grishin,et al.  Chemoselective Reduction of Functionalized 5-Nitroisoxazoles: Synthesis of 5-Amino- and 5-[Hydroxy(tetrahydrofuran-2-yl)amino]isoxazoles , 2014, Synthesis.

[5]  R. Pilli,et al.  Design, synthesis and in vitro evaluation against human cancer cells of 5-methyl-5-styryl-2,5-dihydrofuran-2-ones, a new series of goniothalamin analogues. , 2013, Bioorganic & medicinal chemistry.

[6]  H. Lemcke,et al.  Unusual Tubulin‐Clustering Ability of Specifically C7‐Modified Colchicine Analogues , 2013, Chembiochem : a European journal of chemical biology.

[7]  Qingbiao Yang,et al.  Colorimetric and fluorescent nanofibrous film as a chemosensor for Hg(2+) in aqueous solution prepared by electrospinning and host-guest interaction. , 2012, Chemical communications.

[8]  N. Zefirov,et al.  Heterocyclization of electrophilic alkenes with tetranitromethane revisited: regiochemistry and the mechanism of nitroisoxazole formation , 2012 .

[9]  Joshua A. Bittker,et al.  Development of small-molecule probes that selectively kill cells induced to express mutant RAS. , 2012, Bioorganic & medicinal chemistry letters.

[10]  N. Meanwell.  Synopsis of some recent tactical application of bioisosteres in drug design. , 2011, Journal of medicinal chemistry.

[11]  D. Weiss,et al.  Design, synthesis and bioactivity of simplified taxol analogues on the basis of bicyclo[3.3.1]nonane derivatives , 2008 .

[12]  N. Zefirov,et al.  Ligands of the colchicine site of tubulin: A common pharmacophore and new structural classes , 2007 .

[13]  D. Zaharevitz,et al.  A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. , 2005, Journal of medicinal chemistry.

[14]  V. Yadav,et al.  Reactions on a solid surface. A simple, economical, and efficient acylation of alcohols and amines over Al2O3. , 2004, The Journal of organic chemistry.

[15]  D. Burns,et al.  Identification and characterization of A-105972, an antineoplastic agent. , 2001, Cancer research.

[16]  J. Yadav,et al.  Zinc Promoted Mild and Efficient Method for the Esterification of Acid Chlorides with Alcohols , 1998 .

[17]  E. LaVoie,et al.  Bioisosterism: A Rational Approach in Drug Design. , 1996, Chemical reviews.

[18]  A. Pascual.  Transformations in the Isoxazole Series: Synthesis of Substituted 2-Aminothiazoles† , 1991 .