Modulating arousal to overcome gait impairments in Parkinson’s disease: how the noradrenergic system may act as a double-edged sword

[1]  V. Weerdesteyn,et al.  Evaluation of Compensation Strategies for Gait Impairment in Patients With Parkinson Disease , 2022, Neurology.

[2]  Yohan J. John,et al.  Understanding the effects of serotonin in the brain through its role in the gastrointestinal tract. , 2022, Brain : a journal of neurology.

[3]  J. Shine,et al.  The Contribution of Noradrenergic Activity to Anxiety‐Induced Freezing of Gait , 2022, Movement disorders : official journal of the Movement Disorder Society.

[4]  J. Shine,et al.  The role of the locus coeruleus in shaping adaptive cortical melodies , 2022, Trends in Cognitive Sciences.

[5]  V. Weerdesteyn,et al.  Cortical Correlates of Gait Compensation Strategies in Parkinson Disease , 2022, Annals of neurology.

[6]  Luis F. Ciria,et al.  The brain in flow: A systematic review on the neural basis of the flow state , 2021, Cortex.

[7]  Xiaojun Xu,et al.  Locus coeruleus degeneration is associated with disorganized functional topology in Parkinson’s disease , 2021, NeuroImage: Clinical.

[8]  A. Nieuwboer,et al.  A systematic review on exercise and training-based interventions for freezing of gait in Parkinson’s disease , 2021, NPJ Parkinson's disease.

[9]  B. Bloem,et al.  Perception and Use of Compensation Strategies for Gait Impairment by Persons With Parkinson Disease , 2021, Neurology.

[10]  G. Fink,et al.  Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease. , 2021, Brain : a journal of neurology.

[11]  N. Brüggemann,et al.  Association of Locus Coeruleus and Substantia Nigra Pathology With Cognitive and Motor Functions in Patients With Parkinson Disease , 2021, Neurology.

[12]  M. Breakspear,et al.  Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics , 2021, Nature Neuroscience.

[13]  A. Bakker,et al.  The Neuroscience of the Flow State: Involvement of the Locus Coeruleus Norepinephrine System , 2021, Frontiers in Psychology.

[14]  J. Duysens,et al.  Parkinson's Kinesia Paradoxa Is Not a Paradox , 2021, Movement disorders : official journal of the Movement Disorder Society.

[15]  R. Helmich,et al.  Stress and mindfulness in Parkinson’s disease – a survey in 5000 patients , 2021, NPJ Parkinson's disease.

[16]  J. Rothwell,et al.  Variability of Movement Disorders: The Influence of Sensation, Action, Cognition, and Emotions , 2020, Movement disorders : official journal of the Movement Disorder Society.

[17]  R. Helmich,et al.  Stress and Mindfulness in Parkinson's Disease: Clinical Effects and Potential Underlying Mechanisms , 2020, Movement disorders : official journal of the Movement Disorder Society.

[18]  K. E. Ehgoetz Martens,et al.  Heart Rate Changes Prior to Freezing of Gait Episodes Are Related to Anxiety. , 2020, Journal of Parkinson's disease.

[19]  B. Bloem,et al.  Perceptions of Compensation Strategies for Gait Impairments in Parkinson’s Disease: A Survey Among 320 Healthcare Professionals , 2020, Journal of Parkinson's disease.

[20]  J. Hausdorff,et al.  Behavioural manifestations and associated non-motor features of freezing of gait: A narrative review and theoretical framework , 2020, Neuroscience & Biobehavioral Reviews.

[21]  I. Toni,et al.  Cognitive load amplifies Parkinson's tremor through excitatory network influences onto the thalamus. , 2020, Brain : a journal of neurology.

[22]  B. Bloem,et al.  Freezing of Gait and its Levodopa Paradox. , 2019, JAMA neurology.

[23]  W. Oertel,et al.  The locus coeruleus: Another vulnerability target in Parkinson's disease , 2019, Movement disorders : official journal of the Movement Disorder Society.

[24]  Oliver Speck,et al.  Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases , 2019, Brain : a journal of neurology.

[25]  F. Blandini,et al.  Parkinson’s Disease in Women and Men: What’s the Difference? , 2019, Journal of Parkinson's disease.

[26]  V. Mok,et al.  Effects of Mindfulness Yoga vs Stretching and Resistance Training Exercises on Anxiety and Depression for People With Parkinson Disease: A Randomized Clinical Trial. , 2019, JAMA neurology.

[27]  Paolo Bonato,et al.  Gait impairments in Parkinson's disease , 2019, The Lancet Neurology.

[28]  J. Shine.  Neuromodulatory Influences on Integration and Segregation in the Brain , 2019, Trends in Cognitive Sciences.

[29]  A. Nieuwboer,et al.  Functional MRI to Study Gait Impairment in Parkinson’s Disease: a Systematic Review and Exploratory ALE Meta-Analysis , 2019, Current Neurology and Neuroscience Reports.

[30]  M. Hallett,et al.  Compensation Strategies for Gait Impairments in Parkinson Disease: A Review. , 2019, JAMA neurology.

[31]  Vincent Breton-Provencher,et al.  Active control of arousal by a locus coeruleus GABAergic circuit , 2018, Nature Neuroscience.

[32]  Laura Avanzino,et al.  Relationships between gait and emotion in Parkinson's disease: A narrative review. , 2018, Gait & posture.

[33]  Russell A. Poldrack,et al.  Catecholaminergic manipulation alters dynamic network topology across cognitive states , 2018, Network Neuroscience.

[34]  L. Trudeau,et al.  On Cell Loss and Selective Vulnerability of Neuronal Populations in Parkinson's Disease , 2018, Front. Neurol..

[35]  Rebekah L. Blakemore,et al.  Stress-evoking emotional stimuli exaggerate deficits in motor function in Parkinson's disease , 2018, Neuropsychologia.

[36]  Gaia Bonassi,et al.  Gait initiation is influenced by emotion processing in Parkinson's disease patients with freezing , 2018, Movement disorders : official journal of the Movement Disorder Society.

[37]  D. Weinshenker.  Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease , 2018, Trends in Neurosciences.

[38]  Julie M. Hall,et al.  Predicting the onset of freezing of gait: A longitudinal study , 2018, Movement disorders : official journal of the Movement Disorder Society.

[39]  Stefano Panzeri,et al.  The Locus Coeruleus Is a Complex and Differentiated Neuromodulatory System , 2018, Neuron.

[40]  R. Helmich,et al.  Entangled cerebral networks in Parkinson's disease. , 2017, Brain : a journal of neurology.

[41]  Michael Breakspear,et al.  The modulation of neural gain facilitates a transition between functional segregation and integration in the brain , 2017, bioRxiv.

[42]  H. Braak,et al.  Neuropathological Staging of Brain Pathology in Sporadic Parkinson’s disease: Separating the Wheat from the Chaff , 2017, Journal of Parkinson's disease.

[43]  K. Takakusaki.  Functional Neuroanatomy for Posture and Gait Control , 2017, Journal of movement disorders.

[44]  G. Russell,et al.  The effects of a mindfulness-based lifestyle program for adults with Parkinson’s disease: a mixed methods, wait list controlled randomised control study , 2016, BMC Neurology.

[45]  R. Helmich,et al.  Cognitive Stress Reduces the Effect of Levodopa on Parkinson's Resting Tremor , 2016, Clinical Neurophysiology.

[46]  N. Pachana,et al.  Mindfulness for Motor and Nonmotor Dysfunctions in Parkinson's Disease , 2016, Parkinson's disease.

[47]  Hyo Seon Jeon,et al.  Tremor frequency characteristics in Parkinson's disease under resting-state and stress-state conditions , 2016, Journal of the Neurological Sciences.

[48]  Q. Almeida,et al.  Anxiety‐provoked gait changes are selectively dopa‐responsive in Parkinson's disease , 2015, The European journal of neuroscience.

[49]  L. Defebvre,et al.  Gait and attentional performance in freezers under methylphenidate. , 2015, Gait & posture.

[50]  Colin G. Ellard,et al.  Does Anxiety Cause Freezing of Gait in Parkinson's Disease? , 2014, PloS one.

[51]  Michael J Frank,et al.  Freezing of gait in Parkinson's disease is associated with functional decoupling between the cognitive control network and the basal ganglia. , 2013, Brain : a journal of neurology.

[52]  K. Takakusaki.  Neurophysiology of gait: From the spinal cord to the frontal lobe , 2013, Movement disorders : official journal of the Movement Disorder Society.

[53]  S. Sakoda,et al.  L-threo-3,4-dihydroxyphenylserine (L-DOPS) co-administered with entacapone improves freezing of gait in Parkinson's disease. , 2013, Medical hypotheses.

[54]  G. Halliday,et al.  An evidence base for noradrenergic deficits in Parkinson's disease , 2012, Movement disorders : official journal of the Movement Disorder Society.

[55]  R. Oostenveld,et al.  Stress-Related Noradrenergic Activity Prompts Large-Scale Neural Network Reconfiguration , 2011, Science.

[56]  Laura Bonanni,et al.  Paradoxical kinesia in parkinsonian patients surviving earthquake. , 2010, Movement disorders : official journal of the Movement Disorder Society.

[57]  Talia Herman,et al.  Reliability of the new freezing of gait questionnaire: agreement between patients with Parkinson's disease and their carers. , 2009, Gait & posture.

[58]  S. Lewis,et al.  A pathophysiological model of freezing of gait in Parkinson's disease. , 2009, Parkinsonism & related disorders.

[59]  E. Szabadi,et al.  Functional Neuroanatomy of the Noradrenergic Locus Coeruleus: Its Roles in the Regulation of Arousal and Autonomic Function Part II: Physiological and Pharmacological Manipulations and Pathological Alterations of Locus Coeruleus Activity in Humans , 2008, Current neuropharmacology.

[60]  Ilana Schlesinger,et al.  Paradoxical kinesia at war , 2007, Movement disorders : official journal of the Movement Disorder Society.

[61]  H. Ellgring,et al.  Predictors of freezing in Parkinson's disease: A survey of 6,620 patients , 2007, Movement disorders : official journal of the Movement Disorder Society.

[62]  G. Kwakkel,et al.  Cueing training in the home improves gait-related mobility in Parkinson’s disease: the RESCUE trial , 2007, Journal of Neurology, Neurosurgery & Psychiatry.

[63]  P. Calabresi,et al.  A convergent model for cognitive dysfunctions in Parkinson's disease: the critical dopamine–acetylcholine synaptic balance , 2006, The Lancet Neurology.

[64]  Abraham Lieberman,et al.  Are Freezing of Gait (FOG) and panic related? , 2006, Journal of the Neurological Sciences.

[65]  Jonathan D. Cohen,et al.  Adaptive gain and the role of the locus coeruleus–norepinephrine system in optimal performance , 2005, The Journal of comparative neurology.

[66]  Jonathan D. Cohen,et al.  An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. , 2005, Annual review of neuroscience.

[67]  Chris Zarow,et al.  Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases. , 2003, Archives of neurology.

[68]  Jacob D. Dodson.  The relation of strength of stimulus to rapidity of habit-formation in the kitten. , 1915 .

[69]  Johannes Keller,et al.  The Flow Experience Revisited: The Influence of Skills-Demands-Compatibility on Experiential and Physiological Indicators , 2016 .

[70]  Thomas Stephan,et al.  Supraspinal locomotor control in quadrupeds and humans. , 2008, Progress in brain research.

[71]  Lawrence W. Cole,et al.  The relation of strength of stimulus to rate of learning in the chick. , 1911 .