论文信息 - Trialkylamine-mediated intramolecular acylation of alkenes with carboxylic acid chlorides.

Trialkylamine-mediated intramolecular acylation of alkenes with carboxylic acid chlorides.

Trialkylamine-mediated intramolecular cyclization of pent-4-enoyl chlorides was studied. Substitution with a tertiary alkyl group at the 2-position gave cyclopent-2-en-1-ones, while substitution with an aromatic group gave enol esters, which were formed by O-acylation of initially formed 3-chlorocyclopentanones with ketenes.

H. Ishibashi | J. Matsuo | Shun Sasaki | Takaya Hoshikawa

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