Co-expression of EGF receptor, TGFα and S6 kinase is significantly associated with colorectal carcinomas with distant metastases at diagnosis
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M. Papotti | S. Cappia | L. Dogliotti | M. Volante | E. Bacillo | M. Tampellini | I. Alabiso | M. Longo
[1] R. Berardi,et al. Epidermal growth factor receptor (EGFR) downstream signalling pathway in primary colorectal tumours and related metastatic sites: optimising EGFR-targeted treatment options , 2007, British Journal of Cancer.
[2] N. Enomoto,et al. EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus , 2006, International journal of cancer.
[3] Silvia Benvenuti,et al. Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study. , 2005, The Lancet. Oncology.
[4] L. Schwartz,et al. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[5] C. Ko,et al. Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. , 2005, Journal of the National Cancer Institute.
[6] J. Hauser,et al. Autocrine Transforming Growth Factor α Regulates Cell Adhesion by Multiple Signaling via Specific Phosphorylation Sites of p70S6 Kinase in Colon Cancer Cells* , 2004, Journal of Biological Chemistry.
[7] R. Hofstra,et al. Genetic alterations in locally advanced stage II/III colon cancer: a search for prognostic markers. , 2004, Clinical colorectal cancer.
[8] S. Störkel,et al. Immunohistochemical Detection of EGFR in Paraffin-embedded Tumor Tissues , 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[9] E. Sabo,et al. Epidermal Growth Factor Receptor, c-MET, β-Catenin, and p53 Expression as Prognostic Indicators in Stage II Colon Cancer , 2004, Clinical Cancer Research.
[10] H. McLeod,et al. Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors. , 2004, International journal of oncology.
[11] E. Sabo,et al. Epidermal growth factor receptor, c-MET, beta-catenin, and p53 expression as prognostic indicators in stage II colon cancer: a tissue microarray study. , 2004, Clinical cancer research : an official journal of the American Association for Cancer Research.
[12] N. Sergina,et al. The Role of Transforming Growth Factor α in Determining Growth Factor Independence , 2003 .
[13] M. Brattain,et al. Integrin alpha2 and extracellular signal-regulated kinase are functionally linked in highly malignant autocrine transforming growth factor-alpha-driven colon cancer cells. , 2003, The Journal of biological chemistry.
[14] N. Sergina,et al. The role of transforming growth factor alpha in determining growth factor independence. , 2003, Cancer research.
[15] B. Spaulding,et al. Epidermal growth factor receptor expression and measurement in solid tumors. , 2002, Seminars in oncology.
[16] N. Goldstein,et al. Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma , 2001, Cancer.
[17] M. Mann,et al. p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[18] Jacques Ferlay,et al. Estimates of the worldwide incidence of 25 major cancers in 1990 , 1999, International journal of cancer.
[19] J. Koudstaal,et al. Clinical relevance of transforming growth factor α, epidermal growth factor receptor, p53, and Ki67 in colorectal liver metastases and corresponding primary tumors , 1998 .
[20] D M Parkin,et al. Cancer incidence and mortality in the European Union: cancer registry data and estimates of national incidence for 1990. , 1997, European journal of cancer.
[21] N. Normanno,et al. Epidermal growth factor-related peptides and their receptors in human malignancies. , 1995, Critical reviews in oncology/hematology.
[22] C. Bucana,et al. Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.
[23] J. Willson,et al. Autocrine transforming growth factor-alpha is associated with progression of transformed properties in human colon cancer cells. , 1993, The Journal of biological chemistry.
[24] N. Quenville,et al. Prognostic markers of colorectal cancer: An evaluation of DNA content, epidermal growth factor receptor, and Ki‐67 , 1992, Journal of surgical oncology.