The impact of optical radiation of femtosecond duration on human glial cells

The paper presents the results of the studies of influence of optical radiation with wavelengths of 520 and 780 nm on human glial cells (U251) at the range of exposure times ~ 1-15 min. It was found that after the first minute of irradiation at the wavelength of 780 nm, the relative number of apoptotic cells significantly increased. The result corroborates the concept of biological hazard of optical radiation for tumor cells, and suggests that the approach has a great potential in clinical application for the treatment of human glioma.

[1]  M. Chopp,et al.  Photodynamic Therapy with Photofrin Reduces Invasiveness of Malignant Human Glioma Cells , 2002, Lasers in Medical Science.

[2]  Michael R. Hamblin,et al.  Mechanisms of low level light therapy , 2006, SPIE BiOS.

[3]  J. Tonn,et al.  The brain slice chamber, a novel variation of the Boyden Chamber Assay, allows time-dependent quantification of glioma invasion into mammalian brain in vitro , 2005, Journal of Neuro-Oncology.

[4]  C. Hill,et al.  Transplantation of Adult Rat Schwann Cells into the Injured Spinal Cord. , 2018, Methods in molecular biology.

[5]  Y. Kondo,et al.  Molecular targeting for malignant gliomas (Review). , 2004, International journal of oncology.

[6]  M Molls,et al.  A comparison of treatment results for recurrent malignant gliomas. , 2000, Cancer treatment reviews.

[7]  G. Broggi,et al.  Primary glial tumor patients treated by combining cis-platin and etoposide , 1991, Journal of Neuro-Oncology.

[8]  G. G. Stokes.  "J." , 1890, The New Yale Book of Quotations.

[9]  Chris E. Cooper,et al.  Re-evaluation of the near infrared spectra of mitochondrial cytochrome c oxidase: Implications for non invasive in vivo monitoring of tissues , 2014, Biochimica et biophysica acta.

[10]  J. Pontén.  Neoplastic Human Glia Cells in Culture , 1975 .

[11]  P. Horan,et al.  Fluorescent cell labeling for in vivo and in vitro cell tracking. , 1990, Methods in cell biology.

[12]  W. Hickey,et al.  Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumour model , 2011, ASN neuro.

[13]  David A Jaffray,et al.  Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements☆ , 2017, Advanced drug delivery reviews.

[14]  G. Mills,et al.  Inhibition of Akt survival pathway by a small-molecule inhibitor in human glioblastoma , 2006, Molecular Cancer Therapeutics.

[15]  T. Karu,et al.  Primary and secondary mechanisms of action of visible to near-IR radiation on cells. , 1999, Journal of photochemistry and photobiology. B, Biology.

[16]  P ? ? ? ? ? ? ? % ? ? ? ? , 1991 .

[17]  T. Karu,et al.  Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IR‐A radiation , 2010, IUBMB life.

[18]  Y Iwamoto,et al.  A rapid in vitro assay for quantitating the invasive potential of tumor cells. , 1987, Cancer research.

[19]  Shaoshan Hu,et al.  Apoptotic effect of sonodynamic therapy mediated by hematoporphyrin monomethyl ether on C6 glioma cells in vitro , 2009, Acta Neurochirurgica.

[20]  Xiaodan Jiang,et al.  In vitro photodynamic therapy on human U251 glioma cells with a novel photosensitiser ZnPcS4-BSA , 2010, British journal of neurosurgery.

[21]  Henry Hirschberg,et al.  Effects of ALA‐mediated photodynamic therapy on the invasiveness of human glioma cells , 2006, Lasers in surgery and medicine.

[22]  S. DeArmond,et al.  Development of an in vitro extracellular matrix assay for studies of brain tumor cell invasion. , 1994, Journal of Neuro-Oncology.

[23]  P. Cochat,et al.  Et al , 2008, Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.

[24]  Donald Wlodkowic,et al.  Real‐time cell viability assays using a new anthracycline derivative DRAQ7® , 2013, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[25]  Mikhail Khodzitsky,et al.  Investigation of terahertz radiation influence on rat glial cells. , 2017, Biomedical optics express.