A halogen ion-selective phosphorescence turn-on probe based on induction of Pt-Pt interactions.

Square-planar cyclometalated platinum(ii) complexes have been found to serve as turn-on phosphorescent probes selectively for biological halogen ions. This is based on the halogen ion induced self-assembly of Pt(ii) compounds in aqueous media, resulting in intermolecular Pt-Pt interaction associated emission.

[1]  I. Shin,et al.  A lysosomal chloride ion-selective fluorescent probe for biological applications† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc04084b , 2018, Chemical science.

[2]  Zhao Gao,et al.  Multicomponent Assembled Systems Based on Platinum(II) Terpyridine Complexes. , 2018, Accounts of chemical research.

[3]  C. Leung,et al.  A long-lived peptide-conjugated iridium(iii) complex as a luminescent probe and inhibitor of the cell migration mediator, formyl peptide receptor 2 , 2018, Chemical science.

[4]  Matthew D Brady,et al.  Visible Light Driven Bromide Oxidation and Ligand Substitution Photochemistry of a Ru Diimine Complex. , 2018, Journal of the American Chemical Society.

[5]  G. Cheng,et al.  Highly phosphorescent platinum(ii) emitters: photophysics, materials and biological applications , 2016, Chemical science.

[6]  Z. Su,et al.  Anion-specific aggregation induced phosphorescence emission (AIPE) in an ionic iridium complex in aqueous media. , 2015, Chemical communications.

[7]  D. Genovese,et al.  Recent Advances in Phosphorescent Pt(II) Complexes Featuring Metallophilic Interactions: Properties and Applications , 2015 .

[8]  Vonika Ka-Man Au,et al.  Light-Emitting Self-Assembled Materials Based on d(8) and d(10) Transition Metal Complexes. , 2015, Chemical reviews.

[9]  B. Tang,et al.  A turn-on fluorescence probe for imaging iodide in living cells based on an elimination reaction. , 2015, Chemical communications.

[10]  Ping Li,et al.  Quantitative fluorescence ratio imaging of intralysosomal chloride ions with single excitation/dual maximum emission. , 2014, Chemistry.

[11]  S. Amatori,et al.  Modulating the sensor response to halide using NBD-based azamacrocycles. , 2014, Inorganic chemistry.

[12]  L. Braverman,et al.  Consequences of excess iodine , 2014, Nature Reviews Endocrinology.

[13]  C. Smythe,et al.  Dinuclear Ruthenium(II) Complexes as Two-Photon, Time-Resolved Emission Microscopy Probes for Cellular DNA , 2014, Angewandte Chemie.

[14]  Weihong Zhu,et al.  Steric hindrance-enforced distortion as a general strategy for the design of fluorescence "turn-on" cyanide probes. , 2013, Chemical communications.

[15]  S. Bernhard,et al.  Cyclometalated platinum(II) diimine complexes: synthetically tuning the photophysical and electrochemical properties. , 2012, Dalton transactions.

[16]  S. Amatori,et al.  Multi-use NBD-based tetra-amino macrocycle: fluorescent probe for metals and anions and live cell marker. , 2012, Chemistry.

[17]  V. Yam,et al.  Phosphorescent molecular tweezers based on alkynylplatinum(II) terpyridine system: turning on of NIR emission via heterologous Pt⋯M interactions (M = PtII, PdII, AuIII and AuI) , 2012 .

[18]  J. Roy,et al.  Carbazole-thiosemicarbazone-Hg(II) ensemble-based colorimetric and fluorescence turn-on toward iodide in aqueous media and its application in live cell imaging. , 2012, Organic & biomolecular chemistry.

[19]  Fang Zeng,et al.  A fluorescence turn-on sensor for iodide based on a thymine-Hg(II)-thymine complex. , 2011, Chemistry.

[20]  K. Ohkubo,et al.  Phosphorescent sensor for biological mobile zinc. , 2011, Journal of the American Chemical Society.

[21]  Caihong Zhang,et al.  Screening iodide anion with selective fluorescent chemosensor , 2011 .

[22]  C. Chung,et al.  Reversible pH- and solvent-responsive micelle-mediated self-assembly of platinum(II) terpyridyl-based metallo-supramolecular diblock copolymers. , 2009, Chemical communications.

[23]  V. Yam,et al.  Luminescent alkynylplatinum(II) complexes of 2,6-bis(N-alkylbenzimidazol-2'-yl)pyridine-type ligands with ready tunability of the nature of the emissive states by solvent and electronic property modulation. , 2008, Chemistry.

[24]  V. Yam,et al.  Polyelectrolyte-induced self-assembly of positively charged alkynylplatinum(II)-terpyridyl complexes in aqueous media. , 2008, Chemistry.

[25]  V. Yam,et al.  Luminescent platinum(II) terpyridyl complexes: effect of counter ions on solvent-induced aggregation and color changes. , 2005, Chemistry.

[26]  A. Verkman,et al.  Chloride Concentration in Endosomes Measured Using a Ratioable Fluorescent Cl− Indicator , 2002, The Journal of Biological Chemistry.

[27]  K. Balashev,et al.  SPECTROSCOPIC AND ELECTROCHEMICAL PROPERTIES OF SOME MIXED-LIGAND CYCLOMETALATED PLATINUM(II) COMPLEXES DERIVED FROM 2-PHENYLPYRIDINE , 1995 .

[28]  A S Verkman,et al.  Synthesis and characterization of improved chloride-sensitive fluorescent indicators for biological applications. , 1989, Analytical biochemistry.