Network Understanding of Herb Medicine via Rapid Identification of Ingredient-Target Interactions
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Hao Wang | Zhi-Liang Ji | Jian-Bo Pan | Hao Wang | Jian-Bo Pan | Zhi-Liang Ji | Haiping Zhang | Chi Zhang | Nan Ji | Hai-Ping Zhang | Chi Zhang | Nan Ji
[1] A. Azmi. Adopting network pharmacology for cancer drug discovery. , 2013, Current drug discovery technologies.
[2] David S. Goodsell,et al. The RCSB Protein Data Bank: new resources for research and education , 2012, Nucleic Acids Res..
[3] T. Gao,et al. [Meta-analysis on treatment of non-small cell lung cancer with brucea javanica oil emulsion in combination with platinum-contained first-line chemotherapy]. , 2012, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
[4] J. Feliu,et al. ERCC1 and topoisomerase I expression in small cell lung cancer: prognostic and predictive implications. , 2012, International journal of oncology.
[5] S. Sizemore,et al. The Forkhead Box Transcription Factor FOXC1 Promotes Breast Cancer Invasion by Inducing Matrix Metalloprotease 7 (MMP7) Expression* , 2012, The Journal of Biological Chemistry.
[6] Tamas Hickish,et al. A phase II study of afatinib (BIBW 2992), an irreversible ErbB family blocker, in patients with HER2-positive metastatic breast cancer progressing after trastuzumab , 2012, Breast Cancer Research and Treatment.
[7] Yilong Wu,et al. 非小细胞肺癌的BRAF基因突变及其临床意义 , 2012, Zhongguo fei ai za zhi = Chinese journal of lung cancer.
[8] M. Zorzetto,et al. Targeting EGFR in non-small-cell lung cancer: lessons, experiences, strategies. , 2012, Respiratory medicine.
[9] H. Nielsen,et al. TOP1 gene copy numbers in colorectal cancer samples and cell lines and their association to in vitro drug sensitivity , 2012, Scandinavian journal of gastroenterology.
[10] Susumu Goto,et al. KEGG for integration and interpretation of large-scale molecular data sets , 2011, Nucleic Acids Res..
[11] K. Kunimasa,et al. Successful treatment of non-small cell lung cancer with gefitinib after severe erlotinib-related hepatotoxicity. , 2012, Internal medicine.
[12] Antonio Marchetti,et al. Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[13] H. Ochi,et al. Ubiquitination and downregulation of ErbB2 and estrogen receptor‐alpha by kinase inhibitor MP‐412 in human breast cancer cells , 2011, Journal of cellular biochemistry.
[14] Xue-jun Cui,et al. Classic yin and yang tonic formula for osteopenia: study protocol for a randomized controlled trial , 2011, Trials.
[15] Fan Zhou,et al. Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways , 2011, Evidence-based complementary and alternative medicine : eCAM.
[16] Jing Yuan,et al. 非小细胞肺癌治疗的新靶点:EML4-ALK融合基因 , 2011, Zhongguo fei ai za zhi = Chinese journal of lung cancer.
[17] Jason J Chen,et al. Tumor Cell Selective Cytotoxicity and Apoptosis Induction by an Herbal Preparation from Brucea javanica. , 2011, North American journal of medicine & science.
[18] S. Zienolddiny,et al. A combination of functional polymorphisms in the CASP8, MMP1, IL10 and SEPS1 genes affects risk of non-small cell lung cancer. , 2011, Lung cancer.
[19] Donna D. Zhang,et al. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism , 2011, Proceedings of the National Academy of Sciences.
[20] David S. Wishart,et al. DrugBank 3.0: a comprehensive resource for ‘Omics’ research on drugs , 2010, Nucleic Acids Res..
[21] Jongsun Park,et al. Multiple implications of 3-phosphoinositide-dependent protein kinase 1 in human cancer. , 2010, World journal of biological chemistry.
[22] W. W. Hsiao,et al. The Role of Traditional Chinese Herbal Medicines in Cancer Therapy – from TCM Theory to Mechanistic Insights , 2010, Planta medica.
[23] Zhuomei Lu,et al. 3-Phosphoinositide–Dependent Protein Kinase-1 Regulates Proliferation and Survival of Cancer Cells with an Activated Mitogen-Activated Protein Kinase Pathway , 2010, Molecular Cancer Research.
[24] Gudrun Ulrich-Merzenich,et al. Drug development from natural products: exploiting synergistic effects. , 2010, Indian journal of experimental biology.
[25] H. Yao,et al. Brucea javanica oil induces apoptosis in T24 bladder cancer cells via upregulation of caspase-3, caspase-9, and inhibition of NF-kappaB and COX-2 expressions. , 2010, The American journal of Chinese medicine.
[26] André Schrattenholz,et al. Systems biology approaches and tools for analysis of interactomes and multi-target drugs. , 2010, Methods in molecular biology.
[27] P. Leung,et al. Bruceine D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase. , 2009, Cancer letters.
[28] Yanli Wang,et al. PubChem: a public information system for analyzing bioactivities of small molecules , 2009, Nucleic Acids Res..
[29] A. Tardón,et al. Polymorphism +17 C/G in Matrix Metalloprotease MMP8 decreases lung cancer risk , 2008, BMC Cancer.
[30] Y. Ishikawa,et al. A mouse model for EML4-ALK-positive lung cancer , 2008, Proceedings of the National Academy of Sciences.
[31] A. Hopkins. Network pharmacology: the next paradigm in drug discovery. , 2008, Nature chemical biology.
[32] Jun-quan Yang,et al. [Relationship between expression of caveolin-1 and pERK1/2 and prognosis in non-small cell lung cancer]. , 2008, Zhonghua bing li xue za zhi = Chinese journal of pathology.
[33] Florian Kronenberg,et al. Matrix Metalloproteinase 1 (MMP1) Is Associated with Early-Onset Lung Cancer , 2008, Cancer Epidemiology Biomarkers & Prevention.
[34] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.
[35] Z R Li,et al. MODEL—molecular descriptor lab: A web‐based server for computing structural and physicochemical features of compounds , 2007, Biotechnology and bioengineering.
[36] Meixian Jiang. The TCM stage-oriented treatment for chronic cardiac insufficiency. , 2007, Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
[37] A. Hopkins. Network pharmacology , 2007, Nature Biotechnology.
[38] Y. Z. Chen,et al. Database of traditional Chinese medicine and its application to studies of mechanism and to prescription validation , 2006, British journal of pharmacology.
[39] T. Furukawa,et al. AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer , 2006, Oncogene.
[40] A. Chan,et al. Antiproliferative and apoptosis-inducing activity of Brucea javanica extract on human carcinoma cells. , 2005, International journal of molecular medicine.
[41] Péter Csermely,et al. The efficiency of multi-target drugs: the network approach might help drug design. , 2004, Trends in pharmacological sciences.
[42] Krystal J Alligood,et al. A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib) , 2004, Cancer Research.
[43] J. Pezzuto,et al. Brusatol-induced HL-60 cell differentiation involves NF-κB activation , 2004 .
[44] J. Pezzuto,et al. Antitumor activity of bruceantin: an old drug with new promise. , 2004, Journal of natural products.
[45] J. Pezzuto,et al. Multiple Myeloma Regression Mediated by Bruceantin , 2004, Clinical Cancer Research.
[46] S. Nakagawa,et al. Bruceine B, A Potent Inhibitor of Leukocyte-Endothelial Cell Adhesion , 1997, Inflammation.
[47] J. Pezzuto,et al. Brusatol-induced HL-60 cell differentiation involves NF-kappaB activation. , 2004, Cancer letters.
[48] J. Wolter,et al. A Phase II study of Bruceantin (NSC-165, 563) in advanced malignant melanoma , 2004, Investigational New Drugs.
[49] M. Sliwkowski,et al. Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor* , 2002, The Journal of Biological Chemistry.
[50] E. Green,et al. Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor. , 2002, Blood.
[51] C Y Ung,et al. Computer automated prediction of potential therapeutic and toxicity protein targets of bioactive compounds from Chinese medicinal plants. , 2002, The American journal of Chinese medicine.
[52] Alfonso Bellacosa,et al. AKT plays a central role in tumorigenesis , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[53] Y.Z. Chen,et al. Ligand–protein inverse docking and its potential use in the computer search of protein targets of a small molecule , 2001, Proteins.
[54] R. Lock,et al. The potential tumour suppressor role for caspase-9 (CASP9) in the childhood malignancy, neuroblastoma. , 2001, European journal of cancer.
[55] P. Hasleton,et al. Expression of epidermal growth factor receptor (EGF-R) in human lung tumours. , 1986, British Journal of Cancer.
[56] K. Lee,et al. Anti-inflammatory agents III: Structure-activity relationships of brusatol and related quassinoids. , 1983, Journal of pharmaceutical sciences.
[57] C. Wiseman,et al. Phase II trial of bruceantin in metastatic breast carcinoma , 1982, American journal of clinical oncology.
[58] K. Lee,et al. Antitumor agents XLVI: In vitro effects of esters of brusatol, bisbrusatol, and related compounds on nucleic acid and protein synthesis of P-388 lymphocytic leukemia cells. , 1982, Journal of pharmaceutical sciences.
[59] A. Gonzales,et al. Bruceantin, a novel inhibitor of peptide bond formation. , 1978, Biochimica et biophysica acta.
[60] S. M. Kupchan,et al. Structural requirements for biological activity among antileukemic glaucarubolone ester quassinoids. , 1976, Journal of medicinal chemistry.